查询词典 modifier gene

DATA SYNTHESIS:①Technical choice of gene therapy for bone defect: Human bone morphogenetic protein was the most often used objective gene in the gene therapy for bone defect at present, which had been identified in the models of rabbit, murine, caprine and dog in the application of plerosis of bone defect.

资料综合：①基因治疗骨缺损的技术选择：人骨形态发生蛋白基因是目前骨缺损基因治疗中应用最多的目的基因，已在兔、鼠、羊和狗模型中证实其对骨缺损的修复作用。

The real-time quantitative PCR results showed that the expression level of two genes did not be affected by HHO obviously, whereas, the expression level of CHS gene had down regulation of different degree, except in 1.0 mM of HHO's concentration. It meaned that CHS gene is probably related with the metabolism of allelochemical.4. The Chalcone synthase gene (EaCHS1) of E.

荧光定量PCR的结果表明，萜类代谢途径中的两个关键酶基因的表达水平，没有因为羟基泽兰酮的诱导而表现出显著的差异；CHS基因的表达水平，除了在羟基泽兰酮处理浓度为1.0 mM时的差异不显著之外，在其他处理浓度均有不同程度的下调，说明该基因与化感物质的代谢途径相关。4。

The TC gene was screened from cDNA library of adult Clonorchis sinensis, cloned, expressed and purified. The purified protein of TC gene will be of importance for further research on the biological function of the gene.

通过生物信息学方法由华枝睾吸虫成虫cDNA文库中筛选出TC基因，并成功予以克隆，表达及纯化。

By using wheat with recessive ph gene as parents in wide crosses, new wheat lines with alien chromosome segments, such as TKL1, were obtained. Gene phKL and its combinant have new usefulness for studying on genetic mechanism of homoeologous chromosome pairing and alien gene transfer.

phKL基因及其重组体在染色体配对的遗传作用机制和外源基因转移方面存在新的应用价值。

CML is cytogenetically marked by the philadelphia chromosome, which originates from a reciprocal translocation between chromosome 9 and 22 and is molecularly marked a chimeric bcr-abl gene, resulting from juxta-positive of the abl proto-oncogene on chromosome 9 with the bcr gene, which is normally located on chromosome 22. The chimeric bcr-abl gene expression an 8. 5kb hybrid mRNA transcript giving rise to a 210-KD fusion protein (P210〓) with increased tyrosine kinase activity. P210〓 plays a key role in the pathogenesis of CML. The continuous cell line K562 was established from the pleural effusion of a 53-year-old female with CML in terminal blast crisis, and was a human erythroleukemia line, contained Ph chromosome.

绝大多数慢粒患者白血病细胞中具有Ph染色体，是由9号染色体长臂3区4带和22号染色体长臂1区1带相互易位形成，即t（9；22），使位于9q〓的c-abl原癌基因在第二外显子的5'端断裂并易位到22 q〓的M-bcr基因第2或第3外显子的3'端，形成异常的bcr-abl嵌合基因，该基因转导出异常的mRNA，编码并翻译出P210蛋白，该蛋白具有很强的酪氨酸激酶活性，使粒细胞发生恶性增殖。K562细胞属于慢粒急变、红白血病细胞株，具有Ph染色体。

The results showed that 17 gene fragments were expressed exclusively,26 gene fragments expressed increasingly,and 20 gene fragments expressed decreasingly in incompatible combination compared with either in compatible combination or in control.

结果表明，非亲和性互作中特有的表达片段7条，较亲和性互作及对照表达明显增强的片段21条，表达明显减弱的18条。

Chronic injury of Hepatic, immunologic response and the oxidized of DNA injury may cause gene mutation, carcinogenic gene;oncogene activated , tumor-suppressing gene devitalized, at last result in carcinogenesis.

本课题从基因及蛋白质两方面检测HDAC6在肝癌组织中的表达并探讨其与肝癌发生发展过程中相关的临床病理因素间的相关性，从而期望能够发现肝癌发病及发展和转移新的因素，为肝癌临床治疗提供理论依据。

Possible reasons for this failure may be that obesity is so physiologically complex that no single gene or even handful of genes is likely to have a dispositive role, that examining gene gene interactions is difficult without large numbers of subjects, and that variations among current candidate genes are not the most important contributors to human adiposity.

其他有明显量的变化的基因很难证明，可能的原因就是肥胖是一个复杂的生理变化过程，单个基因或一部分基因会能起到真正的作用，没有大规模人群实验检测基因相互作用还很困难，而且当前的候选基因变化并不是人类肥胖的主要原因。

The present invention relates to a process of producing a functional immunoglobulin superfamily protein, which has at least one disulphide bond when functional, the process comprising the steps of providing a bacterial cell comprising a gene coding for the protein, the gene is expressible in said cell, cultivating the cell under conditions where the gene is expressed, isolating the protein from the cell without reducing it, and subjecting the isolated protein to a folding treatment.

本发明涉及一种产生功能性免疫球蛋白超家族蛋白的方法，此蛋白质在有功能时具有至少一个二硫键，此方法包括如下步骤：提供一种包含编码此蛋白质的基因且此基因可在其中表达的细菌细胞；在使此基因表达的条件下培养此细胞；从该细胞中分离出此蛋白质而不还原它；以及使分离出的蛋白质经受折叠处理。

The SDS-PAGE electrophoresis indicated that all engineered strains containing different expression plasmid could apparently express a 45 kD band specific for daunorubicin C-14 hydroxylase. The expression level of doxA gene was much higher when the doxA gene was under the control of promoter PermE. However, it was found that fd terminator had few effect on the expression of doxA gene.

SDS-PAGE蛋白电泳实验证明，上述五个菌株都能够表达大小约45 kD的柔红霉素C-14羟化酶蛋白，并发现以在PermE启动子控制下的doxA基因表达量相对较高，而终止子对＠中英文摘要 dd基因表达似乎没有影响。

Warden: That's a beautiful dog, but don't bring her again.

那是条漂亮的狗，但是不要再把她带来了。

You get up in the morning – no hangover!

你第二天早上起来的时候—不会宿醉！