查询词典 lethal dose

Methods: 40 cases received the defibrase treatment. The initial dose of defibrase basis on plasma FIB level, the rechallenge time and dose are regulated according to the plasma FIB level , keeping the plasma FIB within 0.5～1.3g/L for one week.

对40例脑梗塞患者使用降纤酶治疗，治疗组给药方法：首次给药根据血浆FIB水平调整给药剂量，再次给药根据血浆FIB 水平调整降纤酶的使用剂量及使用时间。

Methods Dose measurement system(Diamentor K1)equipped with DSA machine(Angiostar-Plus,Seimens,Gemany),analyzed dose-aera-production(cGycm2)and entering doseof 432 patient having received interventional vascular radiology for diagnosis and treatment regressively.

方法采用Angiostar-Plus型DSA机随机配置的剂量测量系统(Diamentor K1)，回顾性分析432例经血管途径介入诊治的面积剂量乘积(DAP，cGycm2)和入射剂量。

Results EROD activities in liver of wild crucian from Zhangtan, Jiangjunyan, Fuyang and Wenyan (23.51±4.17, 16.79±7.39, 18.74±5.16, 18.65±8.86 nmol/) were significantly higher than that of Jiekou (7.84±2.42 nmol/g promin), and no difference was observed between the other sites and Jiekou. Three dose groups (0.25, 0.50, 1.00L/dish water sample extracts) were used in Ames test. Reversional mutation rate of TA98 colony exposed to extracts from Zhangtan was 2.21, 3.39, 6.95 without S9, and 2.70, 4.07, 6.23 with S9, respectively. The revesional mutation of TA100 colony was 2.55, 2.81, 5.36 without S9, and 1.73, 2.86, 4.14 with S9, respectively. Reversional mutation rate of TA98 colony exposed to 1.00L/dish extracts from Jiangjunyan with S9 was 2.22, and there was a dose-response relationship in reversional colony count. Ames tests of the other extracts were negative.

结果 樟潭、将军岩、富阳、闻堰点位野生鲫鱼肝EROD酶活性分别为(23.51±4.17)，(16.79±7.39)，(18.74±5.16)，(18.65±8.86)nmol/，明显高于街口[(7.84±2.42)nmol/]，其他点位与对照比较差异无统计学意义；樟潭水样浓集物在浓度为0.25，0.50，1.00 L/皿时在不加与加S9条件下，TA98回变菌落突变率MR值分别为2.21，3.39，6.95，2.70，4.07，6.23；TA100回变菌落MR值分别为2.55，2.81，5.36，1.73，2.86，4.14；Ames试验结果为明显阳性；将军岩水样浓集物在浓度为1.00 L/皿且加S9条件下TA98MR值为2.22，且在浓度为0.25，0.50，1.00 L/皿加S9条件下TA98回变菌落数呈剂量－反应关系，MR值分别为0.88，1.98，2.22；Ames试验结果为弱阳性；其他点位均为阴性。

Methods: Liver injure rat models were made by alcohol, the high-dose and low-dose ZhiGanQing Capsule were continuously watered by for 8 weeks, the contents of AST、ALT and TG were detected separatedly, and the hepatic pathology was observed too.

采用白酒复制大鼠肝损伤模型，脂肝清胶囊按高、低剂量灌胃，连续8周，测定血清天冬氨酸转氨酶、丙氨酸转氨酶及甘油三酯的含量，并观察肝脏的病理组织学改变。

The HIRFL (heavy ion research facility in Lanzhou)will be used as the injector. For the shielding design of CSR, the secondary neutrons due to the ion beam loss,their spectra and angular distributions were estimated based on the experimental results. The dose equivalent outside the shielding surface and in the surrounding environment and the neutron skyshine dose equivalent were also estimated in this study.

为了CSR的屏蔽设计，本文利用现有的实验数据计算了由于束流损失产生的中子及其能谱、角分布，同时也估算了屏蔽体外表面的中子剂量、环境中子剂量及天空返照中子剂量。

Under inverted microscope, stereognosis of neurons died down, there were blank bulb in the neurons, dark particle were seen in the neuritis; the result of MTT test showed that the survival rate of neurons was obviously decreased. Res 40μmol/L increased the survival rate of neurons. Aβ(subscript 25~35) dose-dependently increased the level of MDA, decreased the level of GSH. Res dose-dependently increased the level of GSH, decreased the level of MDA.

结果：Aβ(下标 25~35)在终浓度为2μmol/L时神经元形态有明显的变化，细胞立体感减弱，胞体内空泡形成，细胞突起内可见黑色颗粒状物；细胞的存活能力明显下降，与对照组相比较有显著性差异(P.05)；Res在终浓度40μmol/L时，能明显提高细胞的存活能力。Aβ(下标 25~35)可以明显升高细胞培养上清液中MDA含量，降低GSH的含量；Res可使细胞培养上清液中MDA含量下降，GSH含量增加。

Intravenous medium and high erythromycin and azithromycin dose had obvious exciting effect on spontaneous afferent nerve discharge (erythromycin: 8.34 ± 0.37, 8.54 ± 0.26 vs 7.78 ± 0.23, 7.84 ± 8.27; azithromycin: 8.57 ± 0.43, 8.28 ± 0.38 vs 7.74 ± 0.21, 7.86 ± 0.30) and gastric distention-induced afferent nerve discharge of subdiaphragmatic vagus nerve (erythromycin: 8.54 ± 0.34, 8.61 ± 0.20 vs 8.13 ± 0.36, 8.19 ± 0.21; azithromycin: 8.54 ± 0.30, 8.42 ± 0.21 vs 8.24 ± 0.22, 8.22 ± 0.19), which was statistically significant compared with the control and low dose groups.

结果： 静脉注射小剂量红霉素和阿齐霉素自发放电和对扩胃诱发放电均无显著变化， 20 min后中、大剂量红霉素和阿齐霉素注药后自发放电(红霉素： 8.34±0.37， 8.54±0.26 vs 7.78±0.23， 7.84±8.27；阿齐霉素： 8.57±0.43， 8.28±0.38 vs 7.74±0.21， 7.86±0.30)和对扩胃诱发放电均增强(红霉素： 8.54±0.34， 8.61±0.20 vs 8.13±0.36， 8.19±0.21；阿齐霉素： 8.54±0.30， 8.42±0.21 vs 8.24±0.22， 8.22±0.19)与相应的对照组和小剂量组间差异有统计学意义。

Coadministration of a subeffective dose of L-NNA (3 pmol) or ODQ (10 nmol) with morphine prevented its antiedematogenic effect, but sildenafil (0.15 nmol) rendered a subeffective dose of morphine effective (18 nmol).

亚效应剂量 L-精氨酸(3 pmol)或 ODQ(10 nmol)与吗啡同时注射则会抑制后者的抗水肿作用。

Methods After taking triazolam and distilled water respectively, the mice sleeping-behavior state was observed and recorded; the ratio of sleeping mice was recorded after taking different of ingredients Eucommia ulmoides Oliv. combining with pentobarbital sodium at subliminal dose, and mice latent period and sleeping time at supraliminal dose. Measure the content of interleukin-1β(IL-1β) in mice brain with enzyme-linked immunosorbent assay, weigh spleen and thymus of mice.

通过观察记录日间小鼠睡眠行为状态，戊巴比妥钠阈下催眠剂量实验，延长戊巴比妥钠睡眠时间实验，酶联免疫吸附反应分别检测服用3种不同极性的提取部位、阳性对照物和空白对照组的小鼠脑组织中IL-1β含量，并结合脏器指数等综合分析。

Results At the dosage of 25 mg/kg,AN could induce higher incidence of fetal resorption and death,and decrease the average fetal body weight and le ngth with significant difference(P＜0.05)when compared with neg ative controls.At the dosage of 35 mg/kg,AN could decrease average vital fet us p er litter with significant difference(P＜0.05),and induce chang es of other indexes with highly significant difference(P＜0.0 1).At the dosage of 25 and 35 mg/kg,AN could induce higher teras rate,maternal t eras rate and malformation rate of vital fetus with significant and/or highly s ignificant difference(P＜0.05 or P＜0.01),resp ectively.There existed a dose-effect or dose-response relationship between abo ve indexes and doses.

结果 25 mg·kg-1组死胎率、吸收胎率升高，胎鼠平均体重、体长、尾长减小，与阴性对照组比较差异有显著性(P＜0.05)；35 mg·kg-1组除窝平均活胎数减少，差异有显著性( P＜0.05)，其余各指标与阴性对照组比较差异有非常显著性(P ＜0.01)；25，35 mg·kg-1组畸胎率、母体畸胎率、活胎畸形率升高，与对照组相比差异有显著性和/或非常显著性(P＜0.05或P ＜0.01)，且有明确的剂量效应或剂量反应关系。

There had been a moment during the breakfast meeting, though, after the backslapping and the small talk and when all of us were seated, with Vice President Cheney eating his eggs Benedict impassively and Karl Rove at the far end of the table discreetly checking his BlackBerry, that I witnessed a different side of the man.

那次早餐会期间，在表示过关心和寒暄以后，我们所有人坐了下来，我注意观察了一下，副总统切尼面无表情地吃着班尼迪克蛋（Eggs benedict，源自美国，以英式松饼、火腿、水煮蛋以及荷兰酱组合而成），卡尔。罗夫在餐桌的远端谨慎地经常查看他的黑莓手机，我目睹了他所不为人知的一面。

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