查询词典 lethal dose

Of them 25 cases of oral cancer (G1-2) were randomly divided into trail and control group . The remained 11 cases of nasopharyngeal and maxillary sinus cancer (NPC-MSC, mainly G3-4) were attributed to a third group (1st course: sBRM, then 2nd course: IAC). The order of drug-use of sBRM is: pre-immunomodulation of the reactivity of patient low-dose CTX and PolyI∶C, then in- juring tumor and thereby modulation of its immunogeneity (DDP-PYM regimen , thereafter, reaction enhancement modu- lation [low-dose rhuIL-2, Cimetidine and Indomethacin ] . All drugs, except for CTX, PolyI∶C and Indo, were fractionally delivered in a manner of continously infution in 8-10 hours via a retaining intra-external carotid artery catheter CAVAFIX 335 SPLITTOCAN G14, B.

将其中25例晚期口腔高、中分化鳞癌病人随机分为实验治疗（12例）和对照治疗（13例）两组，实验组采用sBRM疗法，具体用药为：先用小剂量环磷酰胺和聚肌胞对机体反应性作预调变，然后用低剂量DDP-PYM化疗杀伤&致创&癌细胞，使其免疫原性增强并借之诱导肿瘤浸润淋巴细胞，化疗结束后续用小剂量rhuIL-2激活和扩增TIL，特别是其中的T细胞，并借助小剂量西咪替丁、消炎痛调节机体以原发灶为中心的癌受创相关反应。

Take the blood specimen to measure the hepatic and renal function and the tissue biopsy after the active and motive abnormities called toxical manifestation such as posture changes, abnormal sound, uneasiness, quiet, thrill, ataxia, convulsion and so on with toxic dose. Measure the tissue biopsy after death with lethiferous dose. If no toxicity or death occur after the experiment of 12 weeks, measure the hepatic and renal function and the tissue biopsy. There was no rat which had the toxical manifestation such as active or motive abnormities and 3 rats died because of environment or others after the experiment of 12 weeks.

实验中分别测定治疗剂量组小鼠在用药4周，8周，12周后的肝肾功能，并进行组织病理检查；中毒剂量组小鼠在出现行为、动作异常，如改变姿势、叫声异常、不安、安静、震颤、运动失调、惊厥等中毒表现时，取血液标本测定肝肾功能，并进行组织病理检查；致死剂量组小鼠发生死亡后进行组织病理检查；若12周实验结束时无小鼠出现中毒表现或死亡，则取血液标本测定肝肾功能，并进行组织病理检查。12周实验结束时，无小鼠出现动作、行为异常等中毒表现，有3只小鼠因为环境或其它原因发生死亡，病理检查结果正常。

Methods The exposed group carried person dose monitoring meter"TLDmodel469",reading the results used"TLP-hot light lumination dose data disposal system".

暴露组配戴&TLDmodel469&个人剂量监测计，用&TLP-热释光剂量数据处理系统&测读结果。

The pre-treatment of lupeol at the dose of 200 microg/mouse showed 56.05% prevention, and post-treatment at the same dose showed 43.26% prevention, at 96 h time interval, against DMBA induced DNA strand breakage.

间隔96小时，用羽扇豆醇（ 200μg/鼠）行预处理可预防 56.05%DMBA 诱导的 DNA 链断裂。而相同剂量的羽扇豆醇行后处理则可预防 43.26% DMBA 诱导的DNA链断裂。

Methods: AS models were established by injecting rats VD370 000 U / kg one time, feeding high-fat diet, and giving extract B of mallotus furetianus high-dose (0.081 g/kg), low-dose (0.026 g/kg)respectively.

北华大学生理学教研室，吉林吉林 132013 目的：探讨山苦茶提取物B对动脉粥样硬化（atherosclerosis， AS）的防治作用及其机制。

Had rarely or never used protective;(11) MiceGrayAuto had realized the automatic processing of video data from the sexual preference observation system of rats, and MiceGrayManu had accomplished the analysis of images of sexual behaviors of rats;(12) Peripheral given of high dose androgen to female rats before its brain sexual differentiation had caused masculinization and defemininization in female rats, therefore led to homosexuality, and based on the results, we had established the female rat homosexual model;(13) Peripheral given of estrogen to male rats before its brain sexual differentiation had little effects on the sexual preference and sexual behavior of adult rats;(14) Peripheral given of estrogen antagonist to male rats before its brain sexual differentiation had markedly reduced masculine sexual behavior and interfered male sexual preference, but had no effect on feminine sexual behavior, and based on such results, we had established the male rat homosexual model, however the model have to be improved for better sensitivity;(15) The volume of sexually dimorphism nucleus of the preoptic area of the high dose androgen-treated female rats was significantly greater, while on the other hand the volume of AVPV of which was significantly lesser, than the female rat control.

并且有17.79％的男性同性恋者在1年内与异性保持着性关系。但在与异性阴道性交时，绝大多数（92.51％）偶然或不使用安全套；(11)MiceGrayAuto软件实现了大鼠性偏爱视频数据自动处理功能，MiceGrayManu软件实验了大鼠性行为图象分析功能；(12)大脑性分化前高剂量的雄激素有促雌鼠雄性化和去雌性化的作用，并表现为同性性倾向，建立了雌鼠同性恋模型；(13)在雄鼠大脑性分化前外周给予雌激素对成年后的性偏爱和性行为未产生明显影响；(14)在雄鼠大脑性分化前外周给予雌激素拮抗剂明显削弱雄性性行为，阻碍了雄性性偏爱，但雌性行为无明显变化，雄鼠的同性恋模型还有待进一步调整和改进：(15)高剂量雄激素处理的雌鼠SDN-POA体积明显大于对照雌鼠组，而AVPV体积明显小于对照雌鼠组。

During the process of sepsis, trace dose of leptin injected peritoneally significantly improves and stabilizes the hepatic and renal functions. The mechanisms may be related with those intestinal enzymes associated with metabolism of free radicals, mercapto group and purine. Indomethacin exerts a similar role as leptin though at much higher dose.

在脓毒症过程中，微量leptin体外注射可以发挥改善和稳定肝肾功能的明显作用，其机制可能同其影响肠道多种与自由基、巯基和嘌呤代谢相关酶的功能有关，而且吲哚美辛在一定程度上有类似的效应，但所用剂量明显高于leptin水平。

Compared with the control group, the number of TRAP(superscript +) multinuclear cells, TRAP activity and the percentage of bone surface in lutein middle-dose group and lutein high-dose group significantly decreased (P.05). But the expression of RANK mRNA significantly increased (P.05) by treated in different doses of lutein.

诱导培养的破骨细胞形态特征明显；叶黄素中、高剂量组在细胞数量、TRAP活性上与对照组相比有明显统计学差异(P.05)；叶黄素各剂量组在mRNA表达量上与对照组相比有明显统计学差异(P.05)，且呈量效关系。

METHODS: A randomized controlled study was carried out to compare the efficacy of a single dose of 3 or 2 tablets of albendazole composite versus a single dose of 400 mg of albendazole or 10 mg base/kg of pyrantel pamoate for treatment of intestinal nematodiasis including 1 864 cases infected with hookworm, 1 568 cases infected with Ascaris, 1 785 cases in...

对成人钩虫感染者1864例、蛔虫感染者1568例和鞭虫感染者1785例及儿童蛲虫感染者373例，随机分组，比较服用单剂复方阿苯达唑3片或2片与单剂阿苯达唑400mg或噻嘧啶30mg（含基质10mg）／kg的驱虫效果和副作用。

In groups B1, B2 and B3 , after 10 minutes of injecting the additional dose of pentobarbital sodium, pentoxifyllinel in doses of 60mg/kg, 30mg/kg and 15mg/kg were injected respectively. In group C, 125mg/kg of nikethamide was injected after 10 minutes of injecting the additional dose of pentobarbital sodium.

在B1、B2、B3 三组家兔，于再注戊巴比妥钠后(即加注15 mg/kg戊巴比妥钠后)10 分钟，按等比级数分别注射60mg/kg、30mg/kg、15mg/kg 剂量的己酮可可碱；在C 组家兔则注射尼可刹米125 mg/kg 作阳性对照药物。

There are different types of personal loans available.

有许多不同类型的个人贷款优惠。

The above mentioned teaching model of spiral rising can be used to avoid rigidness in teaching.

上述螺旋式上升的教学模式，可以避免教学形成模式後的僵化现象。