查询词典 lethal dose

Really the only affective drug is niacin and it is hard to use because of the flushing but if one is patient and gradually up titrates the dose, getting up to a full therapeutic dose is possible.

事实上唯一有影响的药物是烟酸，但它使用起来比较困难，因为患者可能会发生潮红。但是如果患者通过逐渐加药还是可能把剂量调整至靶剂量的。

Methods: The animals were divided into four groups randomly, including sham operation group, model control group, small dose (30 mg/kg, iv.) and large dose of ammonium oxalate (60 mg/kg, iv.) group. After the operation, ammonium oxalate was administrated and the electroencephalogram (frequency, scope and duration of the epileptic discharge) were recorded, and the survival neurons at the areas of hippocampus CA1 and CA3 was counted.

32只大鼠随机均分为4组：假手术组、模型对照组、小剂量草酸铵实验组(30 mg/kg)和大剂量草酸铵实验组(60 mg/kg)，各组均记录脑电（痫样波频率、幅度及总持续时间），HE切片计数海马CA1、CA3区残存正常神经元。

The results summarized as follows:(1)The main pharmacokinetic parameters Tmax was about 2h, Cmax was 8.365, 7.519, 1.871, 6.485, 4.060μg/mL in blood, gill, kidney, liver, and muscle respectively, after oral administration at a dose of 30 mg/kg; while t1/2 were 8.180~23.249h. These showed that the NFLX absorption was rapid after oral administration of NFLX in Scophthalmus maximus, but the residence time in the fish was long.(2) T1/2 were 74.88~200.45h after oral administration at dose of 30 mg/kg for five consecutive days, which showed that the attenuation of NFLX in the fish body was slow and the residue concentration in the kidney was the highest.

另外，本文测定了大菱鲆成鱼体内NFLX的药物浓度，用MCP-KP药动学程序对所得的药物浓度-时间数据进行分析，结果表明：1单次混饲口灌(30 mg/kg体重日)NFLX，药物在大菱鲆体内的达峰时间为2h，血液、腮、肾脏、肝脏、肌肉达峰浓度分别为：8.365、7.519、1.871、6.485、4.060μg/mL，消除半衰期为8.180～23.249h，说明NFLX在大菱鲆体内吸收较迅速，但滞留时间较长。2连续五天混饲口灌(30 mg/kg体重日)NFLX，消除半衰期为74.88～200.45h，说明混饲口灌NFLX在大菱鲆体内消除缓慢，其中以肾脏中残留最显著。

Methods According to the 4×4 Latin Square design,lytic efficacy was assessed in UK dose[(10 000 U/ml,20 000 U/ml,30 000 U/ml or 40 000 U/ml)]and the timing of Uk infusion(2,4,8,16 h after blood sample taken)and UK lytic time(2,4,8,16 h after UK infusion)in vitro.15 rabbits were subjected to the intracerebral hematoma model for analysing the effect of 2 differents UK dose(10 000 U vs 30 000 U)on brain tissue around hematoma cavity.

目的 探讨尿激酶溶解血凝块的最佳用药剂量、用药时机及药物最佳作用时间，为临床一次性清除血肿提供实验依据。方法采用2个(4×4)拉丁方设计，分析UK剂量[(1万U/ml、2万U/ml、3万U/ml、4万U/ml)]、用药时机(抽血后2、4、8、16 h)和药物作用时间(加UK后2、4、8、16 h)对溶凝效果的影响。

The results show that the suitable material for treatment is the bulb basal plate tissue with a thin part of scales after having been inoculated for 7 days,and regeneration dose is 50～60Gy,the optimum treatment dose for breading is 15～20Gy.In the small bulbs treated with 15Gy and 20 Gy,two mutants were selected,one is shorter with more leaves,the other expands faster.

结果表明，接种7D的外植体更适合作为水仙离体诱变的材料，其不分化剂量为50~60GY，半剂量为15~20GY，在10和15GY处理中，发现了两种小鳞茎突变类型，一种为叶片数增多的矮化突变体，一种为试管小球茎膨大速度加快，所以适宜辐射诱变的剂量为10~20GY。

The results show that die suitable material for treatment is the bulb basal plate tissue with a thin part of scales after having been inoculated for 7 days, and regeneration dose is 50~60Gy, the optimum treatment dose for heading is 15~20Gy. In the small bulls tinted with l5Gy and 20Gy, two mutants were selected, one is shorter with more leaves, the other expands faster.

结果表明，接种7d的外植体更适合作为水仙离体诱变的材料，其不分化剂量为50~60Gy，半剂量为15~20Gy，在10和15Gy处理中，发现了两种小鳞茎突变类型，一种为叶片数增多的矮化突变体，一种为试管小球茎膨大速度加快，所以适宜辐射诱变的剂量为10~20Gy。

The chickens in the 3 dose groups of Chinese herbal medicine were fed with the feedstuff respectively containing 0.5%, 1% and 2% compound Chinese herbal medicine, in chemical pigment group, containing 30 mg/kg of carophyll yellow and 10 mg/kg of carphyll red. The test was carried for 4 successive weeks after adaptive period of 4 days. The color of foot and chest skin was compared. The results indicated that compound Chinese herbal medicine at high and middle doses could markedly increase the colors of foot and breast skin(P 0.05), without significant difference between high and middle dose group.

试验3、剂量筛选将筛选出方3分为低、中、高三个剂量。10日龄三黄肉鸡150只，随机分成5组，对照组饲喂基础日粮，中药的3个剂量组分别在日粮中添加0.5％、1％和2％的方3，化学合成色素组添加30 mg╱kg加丽素黄和10 mg／kg加丽素红，适应期4d后连续饲喂4周，比较各组的增色效果。

"The lack of additional autoinjector doses is a serious concern," the authors write."Nevertheless, pediatricians are advised to prescribe the optimal dose from an autoinjector for each child, even when that dose cannot possibly be precisely 0.01 mg/kg.... For children who weigh less than 10 kg (22 lb), the physician and family should weigh the risks of delay in dosing and dosing errors when an ampule/syringe/needle is used against accepting nonideal autoinjector doses, taking into consideration the specific health needs of the individual child and abilities of the caregivers."

&附加剂量的缺乏受到密切关注，&作者写道，&不过，即使不能按0.01 mg/kg精确计算剂量时，仍建议儿科医师为每个儿童开出自动注射剂最优剂量。。。，对于体重轻于10kg(22lb)的儿童，考虑到儿童个体特殊健康需求及家庭护理人员的能力，当使用的安瓿、针头、注射器与接受非理想自动注射剂量不配套时，医师和家长应当权衡剂量延误及剂量误差风险。&

The EI of different concentrations (7%vol, 8%vol, 9%vol) were iv. infused. The minimum induction dose, the dose of Eisol%, MAC, the cardiac anesthetisia index and the maximal tolerant concentration of end-tidal isoflurane were determined. The animals were autopsied after dead and the main organs were histo-pathologically diagnosed as well.

分别静脉注射7％vol、8％vol、9％volEI测定EI静脉给药的最小诱导剂量、使呼气末浓度达1％的累加用药量DE_(iso1％，MAC以及心脏麻醉指数和最大耐受末呼气浓度，动物死亡后即刻取重要脏器送病理学检查。

On the other hand, the tabular parameters for the treatment planning system to calculate absorbed doses, such as percentage depth dose distribution and cross-profile dose distribution, which are practicable for ordinary field sizes, will be not suitable for small beamlets, especially in inhomogeneity medium.

另外，治疗计划系统使用基于表格的剂量参数(百分深度剂量分布，侧向剂量分布等等)进行剂量计算，这些关系式对大的光子射野是成立的，但却不一定能用于非常小的射野，尤其是在非均匀介质中。

There had been a moment during the breakfast meeting, though, after the backslapping and the small talk and when all of us were seated, with Vice President Cheney eating his eggs Benedict impassively and Karl Rove at the far end of the table discreetly checking his BlackBerry, that I witnessed a different side of the man.

那次早餐会期间，在表示过关心和寒暄以后，我们所有人坐了下来，我注意观察了一下，副总统切尼面无表情地吃着班尼迪克蛋（Eggs benedict，源自美国，以英式松饼、火腿、水煮蛋以及荷兰酱组合而成），卡尔。罗夫在餐桌的远端谨慎地经常查看他的黑莓手机，我目睹了他所不为人知的一面。

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