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These data demonstrated that tributyrin can efficiently inhibit gastric cancer cell growth by inhibiting DNA synthesis and inducing apoptosis. The tributyrin-induced apoptosis is associated with down-regulation of Bcl-2 expression and up-regulation of Bax expression.

这些结果首次显示tributyrin能有效地通过抑制DNA合成和诱导细胞凋亡达到抑制胃癌细胞生长的作用,细胞凋亡与Bcl-2表达量下调和Bax表达量上升有关。

The expression of p-p38 and Rho GDIαwas upregulated in LCA by either low shear stress or hypertension. However, the highest expression of p-p38 and Rho GDIαwas observed in LCA of low shear stress accompanied by hypertension.(4) Effect of low shear stress on both decreasing apoptosis and increasing proliferation of VSMCs in LCA was reversed by tributyrin, a HDAC inhibitor.

当高血压伴有低切应力时,两者的协同作用诱导p-Akt的表达水平进一步增加;(3)高血压和低切应力都可以诱导颈总动脉p38和Rho GDIα表达增加;当高血压伴有低切应力时,两者的协同作用诱导颈总动脉p38和Rho GDIα表达进一步增加;(4)HDAC抑制剂Tributyrin可以通过抑制VSMCs增殖,促进VSMCs凋亡,在干预低切应力诱导的血管重建中发挥作用。

Systematic aerobic exercise upregulates expression of enzyme genes concerning tricarboxylic acid cycle, and downregulates expression of genes concerning muscle protein synthesis and sphingolipid. It is suggested that aerobic exercise is good to protect human nerves' integrity, exerts positive action on anti-aging and accelerate the aerobic metabolism of lipid materials in vivo.

有氧运动可使三羧酸循环相关酶基因表达上调,肌肉蛋白合成相关基因和神经鞘脂类相关基因表达下调,提示有氧运动有助于保护神经细胞的完整性,对抗衰老有积极作用,同时可加速体内脂类物质有氧代谢。

In the present paper, the Sox gene expression analysis of different tissues from the Trionyx sinensis was studied by using RTPCR, and Sox gene fragments of expression from the testicle, brain and spleen were cloned using RTPCR products.

本文采用RT—PCR技术,研究了中华鳖不同组织Sox基因的表达,并通过PCR直接克隆法,分析了来自睾丸、脑和脾组织中的Sox基因序列。

This experiment was designed to explore the effect of glutamine/ lipopolysaccharide on expression of HSP70 in tissues of Trionyx sinensis and the relation between the function of Gln and it induce the expression of HSP70 in tissues. Twenty-four healthy Trionyx sinensises with similar weight were randomly divided into four groups.

本试验通过研究谷氨酰胺/脂多糖对中华鳖肝脏、脾脏和肠道组织热应激蛋白HSP70表达的影响,考察Gln对中华鳖免疫应激的保护作用与其诱导组织HSP70表达的关系。

It is proved that injection of 500 ugLPS/ kgBW remarkably improves the expression of HSP70 in spleen and liver organization of Trionyx sinensis, while injection of 100 mgGln / kgBW inhibits the expression of HSP70 in intestinal canal, spleen and liver organization.

结果表明:腹腔注射500 μgLPS/kgBW显著增强了中华鳖肝脏和脾脏组织HSP70的表达(P.05),而补充100 mgGln/kg BW抑制了中华鳖肠道、肝脏和脾脏组织HSP70的表达。

Results: The expression of tryptase was negatively correlated to the differential degree of esophageal carcinoma. The positive expression of both tryptase and IL-29 was negatively correlated to the depth of tumor invasion.

结果:食管癌中tryptase的表达与食管癌组织学分级呈显著的负相关性,tryptase和IL-29双染均阳性表达与癌组织浸润深度亦呈负相关性。

Expression of β-catenin in metastatic carcinomas was significantly lower than that in primary colon carcinomas (p.01). expression of e-cadherin in metastatic carcinoma was significantly lower than that in primary colon carcinoma(p.01),especially in tubiform adenocarcinoma and well and moderately differentiated carcinoma.

结果] 原发灶及其淋巴结转移灶中β-结肠术后多久的正常表达率分别为23.46%和4.94%,原发灶中术后多久高于转移灶(p.01),尤其是高中分化病例,转移灶中异位表达率显著高于原发灶(45.68%比28.40%,p.01),尤其是管状腺癌;原发灶中β-cat表达强度显著高于转移灶(p.01)。e-cad的表达强度在原发灶显著高于转移灶(p.01),尤其是管状癌症治疗和高中分化病例。

By the Spearman's correlation analysis, apoptosis of renal tubuli was positively related to Bax protein expression and negatively to Bcl-2 protein expression.

经Spearman's相关性分析,肾小管细胞Bax蛋白表达与肾小管细胞凋亡呈正相关,而Bcl-2蛋白表达则与细胞凋亡呈负相关。

VEGF level is increased continuously in the diabetic kidney of rat. The increased expression of VEGF is mainly located in the glomeruli at the early and middle stages, and is in the tubuli at the middle and late stages. VEGF expression in the diabetic kidney of rat is related to the development of renal changes.

VEGF在糖尿病大鼠肾脏中持续高表达,早中期以肾小球表达上调为主,中后期突出表达在肾小管,其表达变化与糖尿病大鼠肾脏病变发生发展相关。

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推荐网络例句

Objective:To compare the response control and attention of Schizophrenic patients with that of the healthy controls by Integrated Visual and Auditorycontinuous performance test. To quantitate the impairment of cognitive function in patients, and to explore the relationship between cognitive function and the severity of the disorder.

目的:探讨精神分裂症病人在IVA持续操作测试中的反应控制能力、注意力等,并与健康人进行比较,从而量化精神分裂症病人的认知功能损害,并进一步探讨其认知功能与疾病严重程度的关系。

Main effective factors including subcooling degree, mechanical vibration, gas hydrate reformation, environment temperature, noncondensing gas and surfactant are analyzed.

指出过冷度、机械振动、重复生成水合物、环境温度、不凝性气体、添加剂是影响气体水合物生成的主要因素,还对R152a水合物的放冷进行了实验研究。

Water is the construction and development of socio-economic basis,and strategic resources.

水是社会经济建设与发展的的基础性,战略性资源。