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Abnormal expression of PTEN gene was involved in progression of ovarian cancer probably by decreasing cell adhesion and apoptosis, increasing cell mobility and angiogenesis. Reduced expression of PTEN gene was closely associated with tumorigenesis and pathobiological behavior of ovarian endometrioid cancer.

PTEN蛋白表达下调与卵巢恶性肿瘤的组织分化程度、临床病理分期和转移能力相关，与卵巢癌中的子宫内膜样癌PTEN蛋白表达关系更为密切。

In Hp positive group, the expression of IL-10 in active gastritis is lower than that in inactive gastritis, which are different with the expression of COX-2 and iNOS, indicating IL-10 is a protect factor in gastritis, but COX-2 and iNOS may relate to pathopoiesis.

Hp阳性组，IL-10在活动性胃炎粘膜组织中的表达低于非活动性胃炎，COX-2、iNOS在活动性胃炎中的表达显著高于非活动性胃炎，说明IL-10在活动性胃炎的发病中可能起保护作用，而COX-2、iNOS可能与致病过程有关。

Hewever the caspase-3 expression was still very high in cortex. Conclusion: In KA model the hippocampus amygdala plays a key role in epilepsy. Therefore it provides a mimic optimal conditions for human temporal lobe epilepsy study. Its an effective method of studying the development, change and pathopoiesis of epilepsy. There is a close relationship between NPY and epilepsy. The regulation of NPY via VPA may be one of the antiepilepsy mechanism of mechanism of VPA. Moreover NGF can enhance the caspase-3 expression. Excito-amino acid can aggravate the apoptosis, which may be one of the reason for intractability of epilepsy.

KA模型因其海马杏仁核在癫痈中起核心作用，故具有模拟人类颗叶癫痈的理想条件，是研究癫痈发展变化、致痈机理的有效工具，NPY与癫病有着密切的联系，VPA调节NPY有可能是其抗癫痈机理之一，而NGF对caspase一3表达有促进作用，兴奋性氨基酸可造成细胞凋亡的增加，而凋亡细胞的增多有可能是癫痈久治不愈的原因之一。

Results］SVHRP could obviously delay forming a time of seizure susceptibility, and decrease the expression of PENK compared with KA leads to increase the expression of PENK.

结果］蝎毒耐热蛋白干预组的大鼠较单独给予红藻氨酸组的大鼠癫痫敏感性形成率明显降低（P＜0.05），而且前脑啡肽原的表达也明显下降（P＜0.05）。

(1) NSCLC has a higher expression of F1ATPase-α and the expression is on the pericellular membrane of A549 cells, which may provide a new target for molecular therapy of NSCLC.

2F1ATPase-α表达于非小细胞肺癌A549细胞株的细胞膜上，提示有作为靶向药物治疗分子靶点的潜力。

This pattern is characterized by the combination of pro-MMP-2 and membrane type 1 (MT1)-MMP expression, which drie pericellular generation of actie MMP-2 and local degradation of normal lier matrix. In addition there is a marked increase in expression of TIMP-1 leading to a more global inhibition of degradation of fibrillar lier collagens by interstitial collagenases (MMP-1/MMP-13). These pathways play a significant role in the progression of lier fibrosis.

其降解肝正常基质，同时抑制引起肝纤维化的纤维胶原降解，这种情况的特点是前明胶酶A合成和膜型1－MMP表达，使得小叶内细胞激活MMP-2和降解当处的正常肝基质，此外血浆1型组织基质金属蛋白酶抑制剂（TIMP-1）明显升高引起广泛的抑制间隙胶原酶(MMP-1/MMP-13)对纤维肝脏胶原的降解。

A special delaminated expression was observed in the pericystic layer of hepatic hydatid cyst Collagen Ⅰ,Ⅲ and Ⅳ expression in the side of pericystic layer directed to the cyst of parasite(50 0%,37 5% and 40 0%) were lower than those in the side of pericyst...

靠近虫体侧纤维囊壁中，Ⅰ、Ⅲ和Ⅳ型胶原的表达阳性率分别为500%、375%和400%。靠近肝实质侧纤维囊壁中，Ⅰ、Ⅲ和Ⅳ型胶原的表达阳性率分别为875%、825%和850%。Ⅰ、Ⅲ、Ⅳ型胶原在两层中表达的差异均有显著意义(P01，P01，P01)。肝包虫囊肿周围人体纤维囊壁分层，Ⅰ、Ⅲ和Ⅳ型胶原与肝实质侧纤维囊壁的形成有密切关系。

Results In RT-PCR analysis of the peripherial blood, 45%(18 out 40) of CRC patients, 10%(2 out 20) of CRP patients were positive for CEA mRNA, respectively. All 40 healthy individuals were negative for CEA mRNA expression. The detection of CEA mRNA was significantly correlated with TNM stage of CRC patients, while there were no significant relationship between the CEA mRNA expression and the malignant extent of cell differentiation.

结果 40例结肠癌患者外周血中CEA mRNA表达的阳性率为45.0%(18/40)，而健康对照组均为阴性，两者比较有显著性差异(P.01)；20例结肠息肉患者中CEA mRNA表达阳性率为10%(2/20)；CEA mRNA阳性表达率与肿瘤分期相关，而与肿瘤细胞分化程度并不相关。

The area of expression was in basal layer of scar epidermis, perivascular and skin appendages, and the intensity of expression in hypertrophic scar was higher than in keloid.

表达区域在瘢痕表皮的基底膜层、血管和皮肤附件的周围。与凋亡相关基因的表达几乎一致。

FIZZ1 had no effect on the expression of scavenger receptor CD36 in cultured macrophages. FIZZ1 can promote the development of AS by the up-regulation of the expression of SR-A and the phagocytose of fatty substance in VSMCs.

FIZZ1不影响体外培养的巨噬细胞清道夫受体CD36的表达，FIZZ1能促进ox-LDL诱导的体外培养的平滑肌细胞SR-A表达，从而可能加速平滑肌细胞吞噬脂质，促进动脉粥样硬化进展。

Chrysanthemum of 10 thousand birthday is lax to edaphic requirement, with the arenaceous qualitative loam with fecund, good drainage had better.

万寿菊对土壤要求不严，以肥沃。排水良好的砂质壤土为好。

He unstepped the mast and furled the sail and tied it.

他拔下桅杆，把帆卷起，系住。