倒位

Abnormal chromosome was detected in 17 fetuses. Among them, trisome 21, trisome 18, trisome 13, Turner syndrome, Klinefelter syndrome, short arm deletion of chromosome 18, and inverted chromosome 9 were detected in 8, 3, 1, 1, 1, and 2 fetuses, respectively. Abnormal chromosome was found in 5 out of 8 fetuses who received serum screening. Ultrasound showed abnormal chromosome in 11 fetuses.

共诊断17例胎儿染色体异常，其中21三体8例，18三体3例，13三体1例， 1 Turner综合征1例，Klinefelter综合征1例， 18染色体短臂微缺失1例，9号染色体臂间倒位2例(1例来源于母亲)。17例中有8例进行了唐氏儿血清学筛查，5例异常，11例超声检查胎儿有结构异常。

The divergence time of nasuta species was dated to be 1～3 mya, later than the divergence of sibling species D.

倒位、基因转变等事件可能是nasuta亚群遗传分化的主要来源。

It was found that four infrequent chromosome pericentric inversions,including inv(6),inv(7),inv(10),inv(11),each about 0.14%; Other seven inv(9),about 0.98% among 714 patients.

在714例受检的人中，发现罕见的染色体臂间倒位4例，包括inv(6)、inv(7)、inv(10)、inv(11)，各占总数的0.14%；另外有9例inv(9)，占总数的0.98%。

According to the results of the research,the karyotypes of three species of wingless crickets have common deriving,the variation is due to centric fusion and rission,and pericentric inversion.

的染色体作了比较研究，结果显示，3种无翅类蟋蟀的核型具有一定相似性，核型的差异可能是由于臂间倒位和着丝粒的融合和裂解。

Furthermore, heterochromatinization should be an earlier event than pericentric inversion.

另外，从刺鳅的X、Y上结构异染色质的相似分布来看，在性染色体进化过程中，异染色质化发生的时间应该早于臂间倒位。

Results Chromosomal changes were detected in 4 cases by high-resolution G-banding: one case with t(4;6)(q23-24;p21), one case with longer p arm of chromosome 21 (21p+), and two cases with pericentric inversion of chromosome 9 inv(9 which was confirmed by C-banding.

结果用G带分析观察到有染色体改变的4例患者，分别为1例t(4；6)(q23-24；p21)、1例21p+和2例9号染色体臂间倒位。

Compared the similarity and difference of distribution of homologous fragments on X and Y, we suggested that the sex chromosomes of spiny eel have evolved from a pair of homologous ancestral chromosomes, and during the evolution, a pericentric inversion might have occurred on the original Y chromosome, and subsequently terminal regional duplication might have followed, eventually resulting in the differentiation and formation of X and Y chromosomes, then the recombinants between sex chromosomes were repressed, so the sex chromosomes could be inherited steadily.

根据X、Y染色体上同源片段的分布的相似和相异，我们对刺鳅性染色体的分化历程进行了推测，即：刺鳅的性染色体起源于一对原始的同源染色体，通过原Y染色体上的一个明显的臂间倒位，以及染色体末端的异染色质成分的扩增，导致原始Y染色体与X染色体在染色体结构上的分化，从而抑制了X、Y性染色体之间的遗传物质的重组交换，为性染色体的稳定遗传奠定了基础。

Additionally, analysis of G-banding patterns for macrochromosomes of them indicated that there was great difference between NO.1 and NO.2 chromosome, which can be explained by the pericentric inversions.

NO.l染色体，家鸡为m型，而鹌鹑为sm型；NO.4、NO.6、NO.8和Z染色体，家鸡分别为sm、sm、m、m型，而鹌鹑全为t型。G带分析结果显示，家鸡和鹌鹑的G带差异主要反映在NO.1、NO.2染色体上，这可能是由於臂间倒位所致。

Analysis of this pattern revealed 300 inversions and translocations that have occurred since divergence of these two species.

对这种模式的分析发现自这两个物种进化上分支后出现了300个倒位和易位。

For families without inversions, it is easier and more cost-effective to undertake linkage analysis of genetic polymorphism based on PCR.

对于无倒位的家系，利用基因多态性进行遗传连锁分析较为有效可行。

He and Nina moved to California and lived at 2005 Ivar Street, Apt.

他和Nina搬到加州，并在2005年伊瓦尔街，公寓生活。

Droperidol （ potently inhibits transfected HERGchannels and this is the probable mechanism for QT prolongation.

氟哌利多有效地抑制了转染的 HERG 钾通道，可能是 QT 间期延长的机制。