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1、The Entropy、Smoothness、Uniformity and Relation (base on co-occurrence)are significantly difference between the patients and volunteers(p.05).2、The Contrast (base on co-occurrence matrices) and Distance (based on autocovariance coefficients) tend to be higher volunteers, but not reaching statistical significance.3、Among all the thirty-nine features, the most significant difference was obtained using Relation with the pixel distance varied from 1 to 3 pixels.

本实验使用纹理分析的方法研究正常膀胱壁组织和膀胱赘生物组织的纹理特征,并筛选出四种存在显著统计学差异的纹理特征,为后续利用纹理特征研究膀胱肿瘤浸润肌层深度提供了依据。另外,如前所述,目前膀胱肿瘤的诊断主要依靠膀胱镜,但作为一种侵入性操作,膀胱镜并不适合人群疾病普查和患者的治疗后随访。

Seven patients aged 4 to 19 years, with myelomeningocele and high-pressure or poorly compliant bladders, were identified as candidates for cystoplasty. Each patient underwent bladder biopsy, and urothelial and muscle cells were grown in culture and seeded on a biodegradable bladder-shaped scaffold made of collagen, or on a composite of collagen and polyglycolic acid. About 7 weeks later, the autologous engineered bladder constructs were used for reconstruction, and implanted either with or without an omental wrap. After implantation, patients underwent serial urodynamics, cystograms, ultrasounds, bladder biopsies, and serum analyses.

年纪从4到19岁的7位脊髓脊膜膨出、罹有高压或者功能不良膀胱、被鉴定需进行膀胱成形术的病患,每一位病患接受膀胱切片,将上皮与肌肉细胞在膀胱形状的生物可分解的胶原支架或胶原聚羟基乙酸支架上加以培养;大约7周过后,形成一可自体移植的工程膀胱,移植时包覆或者未包覆网膜;移植后,病患进行一系列的尿路动力学、膀胱造影术、超音波、膀胱切片和血清分析。

To investigate the fluorescence dynamic change of protoporphyrin IX in bladder carcinoma cell induced by 5-ALA and the influence of 5-ALA concentration and pH on fluorescence of PpIX. 2. To discuss the biodistribution and express of PpIX in bladder wall of different lesions by method of instilling of 5-ALA into bladder cavity. 3. To discuss the clinical value of the fluorescence diagnosis in early detection of bladder cancer and the radicality of bladder tumor resection under fluorescence cystoscopy.

本研究目的:1了解5-ALA诱导膀胱癌细胞内生原卟啉IX荧光随时间的动力学变化及5-ALA的浓度、pH值对产生PpIX荧光的影响。2通过膀胱灌注5-ALA探讨其所诱导内生PpIX荧光在膀胱上皮中分布及不同病变表达上的差异。3探讨5-ALA诱导荧光膀胱镜检对发现早期膀胱癌的临床应用价值及在荧光膀胱镜下膀胱肿瘤电切治疗的彻底性。

Results CT displayed the lesions located in the bladder neck and triangle area in 7 cases, in the right anterior wall in 1 cases, involve the entire bladder wall in 2 cases. Eight cases showed the local thickening or nodular or flat dune-like shape thickening of the bladder wall, the size of the lesions were 1.0cm × 0.8cm ~ 4.3cm × 5.9cm, two cases showed the diffuse thickening of the bladder wall. Cystal low density were demonstrated in 2 lesions.The bladder exine were smooth in 9 cases.

结果 10例CG中CT表现为膀胱颈部和三角区7例,右前壁1例,累及整个膀胱壁2例。8例CT平扫表现为膀胱壁局限性增厚或呈结节状、扁丘状突向膀胱腔内的软组织密度影,大小1.0cm×0.8cm~4.3cm×5.9cm,2例膀胱壁弥漫性增厚,边缘光整。2例病灶内可见囊性低密度区。9例膀胱外壁光滑。

objective: to investigate diagnosis and treatment choice of detrusor hypoactivity with impaired contractile function on voiding function in benign prostatic hyperplasia.methods:the clinical date of 48 bph patients with dhic were analyzed,including clinical diagnosis,urodynamic parameters,treatment and follow-ups.results:37 patients with detrusor instability and over 40 cmh2o bladder pressure were treated successfully by turp.the time of indwelling suprapubic punctural cystostomy cathter was(1~8)weeks.11cases without di and under 40 cmh2o bladder pressure were treated by suprapubic punctural cystostomy,accepted the test of urodynamics after(1~3)months.7 cases with di were treated successfully by turp,4 cases without di were indwelled suprapubic punctural cystostomy cathter all life.conclusion:dhic worsens the voiding function of the patients with bph,and the test of urodynamic is helpful to diagnose and could provide more convinced evidences for treatment of patients.

分析膀胱过度充盈所致逼尿肌损伤,引起膀胱逼尿肌收缩无力良性前列腺增生48例患者的临床资料,包括诊断,尿动力学检查,治疗及随访结果。结果:37例经尿流动力学检查,诱发存在逼尿肌不稳定,伴膀胱内压达40 cmh2o以上,采取turp,术后留置膀胱造瘘管(1~8)周后全部拔除,排尿通畅。11膀胱内压始终未达到40 cmh2o,且在膀胱注水充盈过程中无逼尿肌不稳定出现,行膀胱造瘘后出院,(1~3)个月后经尿动力学检查复查膀胱逼尿肌收缩力,其中7例膀胱逼尿肌收缩功能有恢复,行经尿道前列腺汽化电切术治愈;剩余4例膀胱逼尿肌收缩功能几乎无任何改善。长期留置膀胱造瘘治疗。结论:良性前列腺增生导致膀胱过度充盈所致逼尿肌损伤,引起膀胱逼尿肌收缩无力患者,术前应用尿流动力学检查对膀胱逼尿肌损伤程度进行认真分析,可进行有针对性的治疗。

Result: Unstable bladder in 9 cases(45%), low compliance bladder in 5 cases (25%), obstruction in the bladder outlet in 11 cases (55%), dyssynergia in detrusor muscle and external urethral sphincter in 7 cases (35%), unstable bladder with obstruction in the bladder outlet in 6 cases, low compliance bladder with obstruction in the bladder outlet in 4 cases , unstable bladder with dyssynergia in detrusor muscle and external urethral sphincter in 2 cases .

结果:不稳定性膀胱9例(45%),低顺应性膀胱5例(25%),膀胱出口梗阻11例(55%),逼尿肌尿道括约肌协同失调7例(35%),其中不稳定膀胱合并膀胱出口梗阻6例,低顺应性膀胱合并膀胱出口梗阻4例,不稳定膀胱合并逼尿肌尿道外括约肌协同失调2例。

Result: Unstable bladder in 9 cases(45%), low compliance bladder in 5 cases (25%), obstruction in the bladder outlet in 11 cases (55%), dyssynergia in detrusor muscle and external urethral sphincter in 7 cases (35%), unstable bladder with obstruction in the bladder outlet in 6 cases, low compliance bladder with obstruction in the bladder outlet in 4 cases , unstable bladder with dyssynergia in detrusor muscle and external urethral sphincter in 2 cases .

结果:不稳定性膀胱9例(45%),低顺应性膀胱5例(25%),膀胱出口梗阻11例(55%),逼尿肌尿道括约肌协同失调7例(35%),其中不稳定膀胱合并膀胱出口梗阻6例,低顺应性膀胱合并膀胱出口梗阻4例,不稳定膀胱合并逼尿肌尿道外括约肌协同失调2例。结论:慢性前列腺炎患者的下尿路症状与不稳定性膀胱、低顺应性膀胱膀胱出口梗阻及逼尿肌尿道外括约肌协同失调有关,了解这些相关因素对治疗有重要的指导意义。

Result: unstable bladder in 9 cases(45%), low compliance bladder in 5 cases (25%), obstruction in the bladder outlet in 11 cases (55%), dyssynergia in detrusor muscle and external urethral sphincter in 7 cases (35%), unstable bladder with obstruction in the bladder outlet in 6 cases, low compliance bladder with obstruction in the bladder outlet in 4 cases , unstable bladder with dyssynergia in detrusor muscle and external urethral sphincter in 2 cases .conclusion : the symptom of inferior urinary tract in patients with chronic prostatitis urodynamic was related to the unstable bladder, low compliance bladder , obstruction in the bladder outlet and dyssynergia in detrusor muscle and external urethral sphincter ,to know the correlation factors do significant benefit in guiding the clinical treatment.

结果:不稳定性膀胱9例(45%),低顺应性膀胱5例(25%),膀胱出口梗阻11例(55%),逼尿肌尿道括约肌协同失调7例(35%),其中不稳定膀胱合并膀胱出口梗阻6例,低顺应性膀胱合并膀胱出口梗阻4例,不稳定膀胱合并逼尿肌尿道外括约肌协同失调2例。结论:慢性前列腺炎患者的下尿路症状与不稳定性膀胱、低顺应性膀胱膀胱出口梗阻及逼尿肌尿道外括约肌协同失调有关,了解这些相关因素对治疗有重要的指导意义。

Result: Unstable bladder in 9 cases(45%), low compliance bladder in 5 cases (25%), obstruction in the bladder outlet in 11 cases (55%), dyssynergia in detrusor muscle and external urethral sphincter in 7 cases (35%), unstable bladder with obstruction in the bladder outlet in 6 cases, low compliance bladder with obstruction in the bladder outlet in 4 cases , unstable bladder with dyssynergia in detrusor muscle and external urethral sphincter in 2 cases .

采用丹迪尿流测定仪对20例慢性前列腺炎患者进行尿流率、充盈性膀胱侧压、压力―流率测定、尿道侧压及肌电图检查。结果:不稳定性膀胱9例(45%),低顺应性膀胱5例(25%),膀胱出口梗阻11例(55%),逼尿肌尿道括约肌协同失调7例(35%),其中不稳定膀胱合并膀胱出口梗阻6例,低顺应性膀胱合并膀胱出口梗阻4例,不稳定膀胱合并逼尿肌尿道外括约肌协同失调2例。

To minimize complications from urine reservoir constructed with an intestinal segment,reticular transplantation of bladder mucosa to an intestinal seromuscular segment was conducted in 3 randomized groups of canines.

为减少肠管膀胱术的并发症,于1994年3~7月,用犬分三组作了膀胱粘膜点状移植于浆肌层肠段重建膀胱的实验。A组:自体膀胱粘膜点状移植于浆肌层肠段形成人工膀胱,B组:在A组基础上一期将输尿管与人工膀胱吻合,C组:将同种异体膀胱粘膜移植于浆肌层肠段。

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He is the most remarkable man that I have ever known.

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