药物学

Along with deep scientific research and continual development of pharmacogenetics and pharmacogenomics,the new era of individual pharmacotherapy will come true in the future.

随着遗传药理学和药物基因组学的深入研究和不断发展，个体化药物治疗的新时代即将到来。

Psychosomatics, official journal of the Academy of Psychosomatic Medicine, focuses on a variety of issues in psychiatry and medicine.

心身医学》杂志，精神病药物研究协会的官方杂志，着重于精神病学和药物方面的各种问题。

Objective: To study pharmacokinetics of levofloxacin and the effect of Chinese herb Achyranthes bidentata on pharmacokinetics of levofloxacin in pathological model of rats with prostatitis.

目的：研究左氧氟沙星(Levofloxacin，LVFX)在前列腺炎大鼠模型体内的药物代谢动力学特征以及LVFX与引经中药怀牛膝联合应用后，怀牛膝&引经&对LVFX在前列腺炎大鼠体内的药动学及组织药物分布的影响。

In this thesis, drug distribution in local tissues after topical administration of the ATPs was investigated with HPLC technique, concentration of ACF in skin and muscle remained high during 12hours. Pharmacodynamic of ATPs was evaluated with diclofenac gel as a control, and it was found that ATPs had stronger anti-inflammatory activity than diclofenac gel.The results of rabbit skin irritation test and Guinea pig skin allergia test make it certain that ATPs is safe for topical administration.

本文利用局部组织活检法考查了大鼠局部应用ATPs后的局部组织分布情况，结果表明药物能在皮肤和肌肉组织中12h维持较高的药物浓度；将所制ATPs与市售双氯芬酸钾凝胶进行了药效学比较，结果表明ATPs的抗炎效果优于英太青；家兔皮肤刺激性试验结果表明，ATPs对完好皮肤无刺激性，对破损皮肤具有轻度刺激；豚鼠过敏性试验结果显示ATPs无致敏性。

Antibiotics are the single largest class of agents that cause idiosyncratic drug-induced liver injury, reports a new study in Gastroenterology, an official journal of the American Gastroenterological Association Institute.

胃肠病学杂志的一个研究表明，抗生素是导致特殊药物引发肝损伤的头等药物。

Results AHS was an acute severe drug reaction with characteristic symptoms, including generalized skin eruption, fever, lymphadenectasis, eosinophilia, and multiple visceral involvement.

结果 AHS是一种急性严重药物反应、临床表现为广泛皮损，伴发热、淋巴结肿大、多脏器受累、嗜酸粒细胞增多等血液学异常为特征的严重药物反应。

A variety of mechanisms determine drug response, such as pharmacokinetic and pharmacodynamic mechanisms.

人体对药物的反应是由很多机制决定的，如药物动力学和药效学机制。

In the light of looking up -finishing-inquiring into the literature,The subject ntegratedly applied the knowledge of botany and phytotomy and Authentication of Chinese Medicines and the experimental technology to study taxonomy and anatomy of Cornus chinense Wanger and its kindred plant.To combine the knowledge of natural medicinal chemistry instrumental analysis,pharmaceutical analysis and experimental technique,Glycosides chemical components of Cornus chinense Wanger and its kindred plant were qualitatively analysised by using TLC.

以文献查阅-整理-调查为基础，综合运用植物学、植物解剖学、中药鉴定学知识与实验技术对川鄂山茱萸及其近缘植物进行分类学处理与解剖学研究，结合天然药物化学、仪器分析、药物分析等学科的知识与实验技术，用TLC定性分析川鄂山茱萸及其近缘植物的苷类化学组分；用HPLC测定川鄂山茱萸不同器官、细胞组织、果实不同采集期的熊果酸、马钱苷的含量并进行色谱条件优化。

Trollius chinensis Bung is a kind of commonly used drug in traditional Mongolian medicine and enjoys great application value in pharmacognosy, pharmaceutical chemistry, pharmacology, pharmacy and clinics. There are extensive foreground to develop new drugs from it.

金莲花为蒙医常用药，在生药学、药物化学、药理学、药剂学和临床等方面都具有很高的应用价值，对其进行药物开发具有广阔的前景。

Many studies dealing with chiral drugs which are administered as their racemates rely on non-stereoselective analytical techniques. It was shown that the use of such an analytical method can lead to the collection of data which may be both quantitatively and qualitatively inaccurate with respect to the individual enantiomers.

一般非对掌选择性的药物分析条件，得到的药物血中浓度是个别镜像异构物的总和，而非个别镜像异构物的血中浓度，因此并无法对於对掌性药品的立体选择性动态学做定性或定量的探讨。

Cynanchum Lingtai apricot production in the average weight 65 grams, the brightly-colored fruit, juicy rich, sweet-sour taste, sweet from the nucleolus, when the late Qing Dynasty famous Shaanxi, Gansu provinces, the Qing imperial court Tongzhi tribute for years.

灵台生产的牛心杏平均单果重65克，果实色泽鲜艳，汁多味浓，甜酸适口，离核仁甜，清末时就驰名陕、甘两省，清同治年间曾为朝廷贡品。

Chenopodium album,Solanum nigrum, and Amaranthus retroflexus were very susceptible to the herbicides. Polygonum persicaria and Abutilon theophrasti were relatively less susceptible to the herbicides, and Lycopersicon esculentum was not susceptible to it. The relationship between reduction rates of weed biomass and PPM values of weed leaves 2,4, and 6 days after treatment was established.

供试的6种杂草对该混剂的敏感性存在显著差异：红心藜Chenopodium album、龙葵Solanum nigrum和反枝苋Amaranthus retroflexus对该混剂最敏感，ED90值分别为47.65、71.67和29.17g/hm2；春蓼Polygonum persicaria和苘麻Abutilon theophrasti敏感，ED90值分别为96.91、114.20g/hm2；而番茄不敏感。