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In this research, we will study the expression and function of TGF-β 1 in acute pancreatitis.

本实验的目的是探讨急性胰腺炎时TGF—β1的表达及其在急性胰腺炎中的作用。

Objective To explore the expression of Fas/FasL in lung tissue of rats with acute pancreatitis.Methods Pancreatitis was induced with3.5%sodium taurocholate by method of Aho et al.

目的 探讨Fas/FasL在鼠急性胰腺炎肺组织中的表达方法大鼠胰胆管逆行注射3.5%牛磺胆酸钠,制作大鼠重症急性胰腺炎并发肺损伤模型。

At present, deeper researches showed that AIP was different from other pancreatitis, and had a variety of clinical features. Therefore, it was attracting more and more attention as an independent disease.

近年来,随着研究的深入,发现自身免疫性胰腺炎与其他胰腺炎相比较有所不同,呈现多种临床特征,因此作为一个独立的临床疾病,受到越来越多的关注。

Patients suit for surgical operation is less than 15%, and 5 years survival rate is less than 4% after resecting tumor by surgical operation.

近年来,影像学技术的发展提高了胰腺癌的检出率,但是对胰腺癌特别是微小胰腺癌诊断的特异性尚不尽人意。

Objective To review the changes of the clinical and the image in15patients with Pancreatic Carcinoma who implantation of 125 I seeds,and analyzed the effectiveness of 125 I.Methods From Oct.2002to Oct2003,with the system of MICK200-TPV radiotive seeds implantation,The 125 I seeds were implanted into15patients with Pancreatic Carcinoma.The number of seed were18~45.The activity of per seed was0.45~0.7mCi.The peˉripheral radiation total dose was60~90Gy7patients were superadded radiotherapy(the doses was30-35Gy).After the seeds implantation.

目的 报告15例胰腺癌 125 I粒子植入治疗后的临床及影像学变化,讨论 125 I粒子对胰腺癌的治疗作用方法自2002年10月~2003年10月,利用MICK200-TPV放射性粒子植入系统,对15例胰腺癌病人植入 125 I粒子,植入粒子18~45颗,每颗粒子活度0.45~0.7mCi,病灶周边剂量60~90Gy.5例植入粒子后补充外放疗30~35Gy。

The organization fixing of apoenzyme subtypes by IHC: The most increasing expressing were cPLA_2 and sPLA_2 in pancreas, they were found all over in the pancreatic acinar cells in 6h after PT, and spread out from the cells in 24h,then decreased after 72h.

用IHC技术对酶蛋白亚型组织定位方面:胰腺内的表达以sPLA_2和cPLA_2增加为主,6h时即遍布于胰腺腺泡细胞;24h时由于胰腺细胞的大量破坏,腺泡细胞外均可见sPLA_2和cPLA_2的高表达;72h后细胞内外sPLA_2和cPLA_2逐渐下降。

Pancreatic necrosis was identified by dynamic contrast-enhanced computerized tomography and operation. Infectious necrosis was confirmed by Grams stain and culture of CT-guided percutaneous aspirates and pancreatic tissue debrided at surgery.

1997年间收治的经动态增强CT或手术证实有胰腺坏死的67例重症胰腺炎患者,感染性胰腺坏死根据CT引导细针穿刺或手术中涂片培养证实。

The present study investigated the effects of a specific COX-2 inhabitor(NS-398) and a selected PPARγagonist on the proliferation and apoptosis of pancreatic cancer SW1990 cell line to examine whether the two non-celltoxicity agents have synergistic anticancer role, so as to establish the experimental bases for application PPARγagonist associating with specific COX-2 inhabitor in treating pancreatic cancer.

本课题研究特异性COX-2抑制剂NS-398和PPARγ激动剂罗格列酮对人胰腺腺癌细胞系SW1990增殖、凋亡的影响,旨在明确两种非细胞毒性药物对胰腺癌有无协同抗癌作用,为临床联合应用特异性COX-2抑制剂和PPARγ激动剂防治胰腺癌提供实验依据。

Our understanding of the pathogenesis of CP has improved in recent years, though important advances that have been made with respect to delineating the mechanisms responsible for the development of pancreatic fibrosis following repeated acute attacks of pancreatic necroinflammation (the necrosis-fibrosis concept).

虽然慢性胰腺炎重要的进展在于阐述反复急性胰腺坏死性炎症后胰囊性纤维化的发生机制方面,但最近几年我们对于慢性胰腺炎发病机理的理解已有所更新。

Our understanding of the pathogenesis of CP has improed in recent years, though important adances that hae been made with respect to delineating the mechanisms responsible for the deelopment of pancreatic fibrosis following repeated acute attacks of pancreatic necroinflammation (the necrosis-fibrosis concept).

虽然慢性胰腺炎重要的进展在于阐述反复急性胰腺坏死性炎症后胰囊性纤维化的发生机制方面,但最近几年我们对于慢性胰腺炎发病机理的理解已有所更新。

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