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Results: Obvious pathologic changes were observed in pancreas and the apoptotic rate of pancreatic cell in SAP groups were much higher than that in the control group(P.01). The mortality rate was 12.5% in 24h, 90% in a week.

结果:SAP组大鼠胰腺发生明显病理损害,SAP时各时点胰腺细胞存在胰腺细胞凋亡,SAP大鼠1周死亡率为90%。

This method can be used as a discriminator among normal,benign and pancreas diseases cancer.

并将此模型应用于胰腺癌的诊断。该模型可以同时判别消化道良性疾病、胰腺炎与胰腺癌。

And the rats in the control were executed at 5 months to observe the develope of pancreatic cancer by macrograph and microscopy, The EnVision TM immunohistochemistry was used to assay the expression of EZH 2 and PTEN in above pancreatic specimens.

较大剂量DMBA置入胰实质内可获得较高胰腺癌发生率,TSA能抑制胰腺癌的发生和生长;EZH 2基因的激活及PTEN基因的失活在大鼠胰腺癌发生中可能起关键作用。

This result reveal that the cell is pancreatic stem cells and pancreatic stem cells do exist in pancreas,It maintains the steady of pancreas by neogenesis and differation. At present,our laboratory can isolate and expand this cell steadily.This study can provide reference for isolation and expansion of pancreatic stem cells.

说明胰腺内存在着多潜能干细胞,本方法分离到胎猪胰腺干细胞,经诱导分化可形成有功能的胰岛样细胞团并释放胰岛素,有望为进一步研究异种胰腺干细胞移植治疗糖尿病提供材料。

To study further the relationship between the variables above-mentioned and the excretion rate of PABA in the urine of the pancreatic carcinoma patients.

结果 胰头癌患者胰腺外分泌功能明显减低,PABA排泄率为(48.83±15.63)%,明显低于对照组(78.88±15.88)%,而重度胰腺炎患者胰腺外分泌功能(48.5±11.39)%也明显低于对照组。

Objective: To investigate the difference of serum biochemical index between preoperative and postoperative examination in the pancreatic cancer patients. To assess the value of relative index in judging the property of pancreatic tumor, and in predicting the prognosis of pancreatectomy ect.

目的:探讨胰腺癌患者手术前后血清生化学指标变化情况,评估相关参数对于胰腺疾病良恶性的判断和预测胰腺癌切除的预后等多方面的应用价值。

The permeability of those 7 antimicrobial dugs in pancreatic juice and pancreatic tissue was not different significantly.

各种抗菌药物的胰腺渗透率差别较大,防治继发胰腺感染宜选用胰腺渗透率强的抗菌药物。

Study on detecting hypermethylation of the related genes in pancreastic juice to diagnose pancreatic diseases INTRODUCTION Pancreatic cancer is still one of the most common malignant cancers to human, and it is the fourth and sixth cause of death in American and Europe, and also the fifth cause of death in Japan, in our country is the tenth cause of death.

胰液中相关基因高甲基化检测在胰腺疾病诊断中的应用研究前言胰腺癌是二十一世纪人类面临的高度恶性肿瘤之一,在北美洲和欧洲分别占癌症死亡原因的第四位和第六位,在日本占第五位,在我国为前10位。90%的胰腺癌患者在诊断后一年内死亡,诊断后平均生存时间为三个月,适合手术者低于15%,手术平均切除病例的术后5年生存率低于4%。

CT examination expression is pancreatic and intumescent 48 (64.5%), density changes 22 (the liquid collects 8 all round 28.9%), pancreas (inside 10.5%), pancreas necrotic 10 (cyst of sex of 14.4%), intercurrent holiday 6 (7.9%), intercurrent abscess 4 (5.2%), intercurrent phlegmon.

CT检查表现为胰腺肿大48例(64.5%)、密度改变22例(28.9%)、胰腺四周液体聚集8例(10.5%)、胰腺内坏死10例(14.4%)、并发假性囊肿6例(7.9%)、并发脓肿4例(5.2%)、并发蜂窝织炎12例(15.8%)、少量胸腔积液18例(23.6%)等影像学改变。

Objective To study the expression of serine protease 2(PRSS2) in cell lines and tissues of pancreatic carcinoma, and provide a new target for early diagnosis and treatment of pancreatic carcinoma.

目的 研究胰腺癌胰液差异蛋白质丝氨酸蛋白酶2(PRSS2)在胰腺癌组织和细胞株中的表达,为临床胰腺癌的早期诊断及治疗提供新靶点。

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