细胞器官

Between P14 and P21,CIAPIN1 immunoreaction in the brain,heart and liverbecame much lower. However,between P21 and P28,CIAPIN1 immunoreactionin the heart,brain,liver and skeletal muscle became much lower,while with thekidney development,CIAPIN1 immunoreaction in the kidney became higher. Invarious tissues from adult mouse,CIAPIN1 immunoreaction could be seen incardiac muscle cell,brain,hepatocyte,epithelium of renal tubule,skeletal muscle,lung tissue,gastric mucosa and gland,acinus lienalis.2. Distribution of CIAPIN1 in normal fetal and adult human tissuesTo reveal the possible physiological role of CIAPIN1,we examined theexpression and distribution of CIAPIN1 in fetal and adult human tissues usingimmunohistochemistry. We found that CIAPIN1 was ubiquitously distributed infetal and adult tissues,and was localized in both the cytoplasm and the nucleus.

然而，在3个月大的成年鼠中，CIAPIN1阳性反应物在心、脑、肝和肾小管中的表达强度要低于P28小鼠；但CIAPIN1阳性反应物在成年鼠骨骼肌中较P28小鼠高。2、CIAPIN1蛋白在人5个月胚胎及成人多器官组织内的表达在人5月胚胎多器官组织中，CIAPIN1阳性反应物见于心脏、胆囊单层柱状上皮和粘膜、结肠粘膜、小肠粘膜和绒毛、肝脏、直肠腺体、胃粘膜、肾上腺束状带、甲状腺滤泡、脾索、胸腺小叶间隔、皮肤真皮层和汗腺、睾丸白膜和间质、脑组织内神经元和神经胶质、肺小支气管和肺泡、骨骼肌、肾脏皮髓质和肾小管、子宫内膜、胰腺腺泡和胰岛、卵巢、输卵管粘膜等绝大多数组织细胞。

During the process of long-time adaptive evolution, wetland plants adopted a series of special strategies to acclimate to salt stress. The main strategies are: 1 life history adjustment, e. g., to adjust seed germination time, implement seed dormancy and viviparity, and change reproductive manner to escape from direct salt stress, 2 morphological adjustment, e. g., to adjust biomass allocation pattern, age stem, defoliate, and carnify vegetative organs to isolate the redundant Na(superscript +) to the inactive-metabolism shoots or exclude the Na(superscript +)from tissues; 3 anatomic adjustment, e. g., to sink stoma, develop aerenchyma, and thicken cuticle and phellogen to maintain normal photosynthesis and respiration; 4 physiological and biochemical adjustment, e. g., to exclude and excrete salt, compartmentalize ions, adjust osmosis, do selective absorption, regulate hormones, and induce antioxidative enzymes to maintain the osmotic equilibrium and eliminate the active oxygen in cell; and 5 molecular level adjustment, e. g., to start up many salt-induced genes to regulate the metabolic responses to salt stress.

在长期的适应进化过程中，湿地植物形成了多种适应盐胁迫的策略，主要有：1生活史方面，植物可通过种子萌发时间的调整、种子体眠、胎生、繁殖方式的改变等逃避盐度的直接伤害；2形态学方面，植物可通过生物量分配模式的调整、茎的老化、落叶及营养器官的肉质化等将多余的Na隔离到代谢不活跃的茎中或将其排出体外；3解剖学方面，植物可通过气孔下陷、发达的通气组织、增加细胞木栓层、角质层及栅栏组织的厚度等以维持植物正常的光合作用和呼吸作用；4生理生化方面，植物可通过离子区隔化、拒盐、泌盐、选择性吸收、渗透调节、激素调节及抗氧化物酶的诱导等来维持细胞内正常的渗透压，清除胞内活性氧分子；5分子水平方面，植物可通过多种与盐胁迫相关的基因来调控细胞内的多种代谢反应。

objective to raise the level of regarding congnition,prevention,diagnosis and therapy on multiple organ dysfunction syndrome.methods report the process and correlative therapy on one case who occured with mods involving 6 organs after hemorrhagic shock lead to heartbeat and respiration stopping suddenly and resuscitated resulting in left nephrostome titanium nip falled off accidentally from left kidney lymphatic fastening.at the same time,the author reviewed correlative literature and introduce the investigative progress about mods.results one case who happened with mods following hemorrhagic shock,heartbeat and respiration stopped suddenly was diagnozed and resuscitaed.6 organ dysfuncted including brain,heart,lung,liver,kidney and the digestive system.after being given therapy integrated chinese and western medicines,allopathy and nutritional treatment,all circadian parameters of the case came back in gear and discharged at last.conclusion the mechanism about mods is very complicated.because of serious infection,hurt and oxygen-lack,excessive inflammatery reaction activates multifarious cell factors and inflammatery mediums,which improve the happen-rate of mods.wiping off pathogeny,providing life-sustain treatment and recognising sirs and mods in time and adopting corresponding therapy,such as treatment integrated chinese and western medicines,can improve the hit-rate of cure on mods.

作者：王静恩，蔡金芳，王志华，谢晓洪多器官功能障碍综合征；中西医结合；治疗；休克，出血性目的提高对多器官功能障碍综合征（multiple organ dysfunction syndrome，mods）的认识、预防、诊断、治疗水平。方法报告成功抢救1例经腹腔镜左肾淋巴管结扎手术后左肾静脉钛夹意外脱落失血性休克，导致心跳呼吸骤停复苏后再手术并发mods累及6个脏器功能衰竭过程及有关治疗，并复习相关文献，介绍目前关于mods的研究进展。结果确诊1例因失血性休克心跳呼吸骤停复苏后并发mods，累及脑、心、肺、肝、肾、血液、胃肠等6个脏器。经积极采取中西医结合对症、支持救治，各生理指标全部恢复正常，康复出院。结论 mods的发生机制非常复杂，在严重感染、创伤、缺氧等打击下，失控的过度炎症反应激活多种细胞因子和炎症介质的释放，使mods发生率升高。尽早去除病因，尽早给予各种生命支持治疗，尽早对可能发生全身炎症反应综合征、mods识别并给予干预治疗，包括中西医结合治疗能改善mods的救治成功率。

The luminescence intensity of suspended immune cells (1×10〓 cells/ml) from peripheral blood, anterior kidney and spleen of grass carp, which were from two groups immunized with being injected Aeromonas hydrophilia and unimmunized respectively, were detected by means of BPCL4 Intelligentized Ultraweak Luminometer, the datum that were dealt with statistics demonstrated that luminescence intensity of the cells from all kinds of immune organs and blood were intensified after the fish were immunized in two weeks and the luminescence intensity from anterior kidney cells was the highest, mitogens had the enhancing effects. Luminol could strengthened luminescence intensity.

把未免疫的和经过嗜水产气单胞菌注射免疫的草鱼外周血、前肾、胸腺和脾脏以及它们的悬浮细胞（密度控制在1×10〓个细胞／ml左右）分别用BPCL4智能化微弱发光测量仪测量各组的发光强度，结果显示：草鱼各类免疫器官与细胞在免疫两周后发光强度增加，肾细胞的发光强度最大；有丝分裂原具有增强作用；化合物鲁米诺能提高发光强度。

It is well-known that for eucaryotic cells, DNA is located in the karyon and can not penetrate to the cytochylema and the tissue fluid because the cell membrane can act as barriers for DNA transportation. Therefore, the appearance of DNA in cell matrix and the serum can indicate that some diseases have taken place. A main reason for cancer occurrence is the mutation of DNA. It may cause the change of the sequence and expression of cancer suppressor genes.

真核细胞的DNA广泛的存在于细胞核内的染色体上，由于核膜的选择性通透作用，使DNA无法分散到其它细胞的亚器官，加之细胞膜的隔离效果，DNA更难扩散到细胞外基质中，因此细胞外基质中DNA含量的增加往往也会预示某些疾病的发生。

This review briefed the relation between apoptosis and acute pancreatitis, investigated the influence of apoptosis on acute pancreatitic organ damage, and analyzed the relation between apoptosis and inflammatory cytokines, oxidative stress, endoplasmic reticulum stress, Notch factor, aiming at revealing the mechanism of apoptosis in acute pancreatitis.

本文简述细胞凋亡与急性胰腺炎之间的关系，探讨细胞凋亡对急性胰腺炎器官损伤的影响，分析细胞凋亡与炎症因子、氧化应激、内质网应激、Notch因子的关系，从而揭示急性胰腺炎细胞凋亡的发生机制。

One hand mechanical obstruct led to the increase of veinous resistance and the obstacle of microcirculation, the other hand the adhesive PMN was activated in excess, the white blood cells released a lot of enzymes, in which PMN-elastase can decompose the components of cell and many albumens, inclusive of immunoglobulin、alexin and fibrication. These components induced the injury of the pancreatic capillary vessels and cell and lysosome enzy made the tissue protein hydrolyze and produced unsaturated fatty acids, which destroyed the structure and function of cellar membrane. The inflammatory cellar factors activate other immunocytes to produce the injury and necrosis of tissue, which aggravated the pathological injury and led to shock、pyaemia and MODS. So ICAM-1 and LFA-1 played an important role in SAP. Frossard found that the expression of ICAM-1 in the rat model, especially in serum、pancreas and lung. All these showed ICAM-1 is an important factor in AP and concomitant lung injury.

胰腺小叶组织局部血管EC首先被激活，ICAM-1表达升高，与被激活的PMN表面表达的LFA-1相结合，&PMN-EC&相互作用加剧，一方面机械性阻塞毛细血管导致静脉阻力增加、微循环障碍；另一方面粘附的PMN过度吞噬或激活，当白细胞吞噬的颗粒不能被封闭隔离，连同细胞内的酶被释放出来，其中的PMN-elastase能够降解细胞基质中各种成分，水解多种蛋白，加重胰腺的毛细血管内皮细胞和腺泡的损伤；释放的溶酶体酶使组织蛋白水解，产生的不饱和脂肪酸引发脂质过氧化方应，破坏细胞膜的结构和功能；释放的炎性细胞因子，激发其他的免疫细胞的功能，导致进一步的组织损伤和坏死，加重SAP的病理损伤，最终导致休克、脓毒血症及多器官功能障碍等严重后果。

These data prove that the enzyme is compartmented in its functional sites, and so provide evidence to support the possible widespread biological function of the enzyme in catalyzing starch breakdown in plant living cells or at least in living cells of plant storage organs.

这些结果明确地展示出甘薯块根生活细胞中β-淀粉酶与其淀粉基质居于同一亚细胞区域内，为β-淀粉酶普遍参与植物生活细胞或贮藏器官生活细胞中的淀粉水解提供了证据。

Results The morphology of endocrine cells in digestive tract was of multiplicity.The density of 5-HT cells was the highest in the colon,but not found in the esophagus,cardia gastric and cecum.The results showed that SS cells were distributed in the pylorus mostly,but not detected in the cardia,colon,cecum and rectum.Gas positive cells were the most in the duodenums,while in the esophagus and cardia was not discovered.In the cardia VIP cells were maximum,but in the esophagus,duodenums and ileum did not appear.

结果 消化道中4种免疫阳性细胞形态多样，大多呈椭圆形和锥体形。5-HT阳性细胞数量以结肠最多，空肠和回肠次之，幽门腺区、十二指肠和直肠较少，食管、贲门腺区、胃底腺区和盲肠中未见；SS阳性细胞在幽门腺区数量最多，贲门腺区、结肠、盲肠和直肠中未见；Gas阳性细胞大量出现于十二指肠，在食管、贲门腺区和盲肠未见；除个别器官未见VIP阳性细胞外，在消化道的其余各段均有分布。

The two can cause ultrastructural pathogenesis widely in many organs and tissues such as hepar, pancreas, lien, ren, pulmo, cerebral, cerebellum, cor, muscular and so on, of them ,caused by i~olates YG97 and Y98 more obvious in epithelial cells of digestive tract and unobvious in epithelial cells of respiratory tract ,but ultrastructural pathogenesis caused by NDV strain F48E8 ,more obvious and more serious in glandularis and muscularis ventriaculi and in epithelial cells of respiratory tract .

将鹅源分离株YG_(97)、鸡源分离株Y_(98)和NDV强毒株F_(48)E_8感染SPF鸡，运用扫描电镜和透射电镜观察该二株病毒对机体细胞的影响，结果显示三株禽副粘病毒均引起机体肝、胰、脾、肾、肺、小脑、大脑、心和肌肉等实质器官组织细胞的超微病变，其中YG_(97)和Y_(98)引起消化道粘膜上皮细胞发生微绒毛脱落、纤毛脱落、分泌颗粒增多、细胞游离面破溃等显著的超微病变，引起气管粘膜上皮细胞的不显著超微病变；F_(48)E_8强毒株引起胃粘膜显著而严重的超微病变；还引起气管粘膜上皮严重的超微病变。

Cynanchum Lingtai apricot production in the average weight 65 grams, the brightly-colored fruit, juicy rich, sweet-sour taste, sweet from the nucleolus, when the late Qing Dynasty famous Shaanxi, Gansu provinces, the Qing imperial court Tongzhi tribute for years.

灵台生产的牛心杏平均单果重65克，果实色泽鲜艳，汁多味浓，甜酸适口，离核仁甜，清末时就驰名陕、甘两省，清同治年间曾为朝廷贡品。

Chenopodium album,Solanum nigrum, and Amaranthus retroflexus were very susceptible to the herbicides. Polygonum persicaria and Abutilon theophrasti were relatively less susceptible to the herbicides, and Lycopersicon esculentum was not susceptible to it. The relationship between reduction rates of weed biomass and PPM values of weed leaves 2,4, and 6 days after treatment was established.

供试的6种杂草对该混剂的敏感性存在显著差异：红心藜Chenopodium album、龙葵Solanum nigrum和反枝苋Amaranthus retroflexus对该混剂最敏感，ED90值分别为47.65、71.67和29.17g/hm2；春蓼Polygonum persicaria和苘麻Abutilon theophrasti敏感，ED90值分别为96.91、114.20g/hm2；而番茄不敏感。