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移植

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Four weeks following the lesions, rats were tested for apomorphine -induced asymmetric rotation.

结果是:实验组的PD鼠,在移植后的12d内旋转数比移植前明显减少,到d15后,旋转数接近移植前水平。

The patients achieved complete remission after induction course would enter the next grouping:the patients,aged 15-45 years, who had suitable donors and transplantation will were assigned to allogeneic stem-cell transplantation,and for the rest,they would be assigned to accept chemotherapy or autologous stem-cell transplantation randomly.CT and ASCT group both received early intensification and consolidation therapy orderly,which contained high-dose methotrexate,intermediate/high-dose cytarabine and high-dose or high-fraction cyclophosphamide,followed by ASCT or re-induction,later consolidation and maintenance chemotherapy for CT group.

符合入组条件的成人非Ph+ALL患者纳入研究,患者接受标准VDCP±L诱导治疗达到完全缓解(complete remission,CR)后进入下一阶段分组研究:年龄≤45岁,有合适供者及移植意愿者接受异基因造血干细胞移植allogeneic stem cell transplantation,Allo-SCT其余患者根据意愿分别接受自体造血干细胞移植(autologous stem cell transplantation,ASCT和化疗Chemotherapy。

It is concluded that (1) there are no relationships between fusion rate and relativeness of the recipient cytoplasm to nucleus donor cells,(2) cytoplast of the goat MII oocyte can support the preimplantation development of SCNT embryos reconstructed with nucleus from other species,(3) the blastocyst rate of close relative inter-species SCNT embryos is higher than that of distant relative inter-species SCNT embryos.

由此结果得出以下结论:(1)山羊M II期卵母细胞胞质与供核细胞之间的亲缘性不影响两者的融合率;(2)山羊M II期卵母细胞的胞质能支持异种间体细胞核移植胚的着床前发育;(3)亲缘关系近的种间核移植胚的囊胚发育率高于亲缘关系远的种间核移植胚的。

Living related transplantation has been performed successfully in some organs such as kidney,liver,lung,small intestine and spleen,etc.In fact,for living related organ transplantation,there is not only scientific foundations but also ethical foundations,that is ,caring for others with human dedicatory spirits.

活体器官移植起源于器官移植技术的最初阶段,目前已经成功开展了肾脏、肝脏、肺脏、小肠、脾脏等器官的活体移植手术,事实表明该技术不仅有其科学依据,而且有其伦理学依据,即以人类自身伟大的奉献精神来关爱他人。

Immunologic reconstitution is delayer than haematogenesis reconstitution after HSCT, and infection and relapse are problems facing us. Thus, immune state and how to reconstitute immune system after HSCT become a hot study.

移植后受者免疫重建迟于造血重建,面临着肿瘤复发和移植后感染的问题,因此移植后如何促进免疫重建成为研究热点。

Some physicochemical therapy as well as nake hepatocytes transplantation can't correct metabolic disarrangement because of severe hepatic diseases, ALF is characteristic of more complications and easily resulting in multiple organs dysfunction , and even multiple organs failure as well as higher mortality. transplant technique of encapsulated hepatocytes can inhibit immune rejection, and quarantee hepatocytes survival, the technique provides a new therapeutic method for ALF.

由于肝脏功能较复杂,一些利用物理、化学方法及裸肝细胞移植来代替肝脏解毒功能,但不足以纠正严重的肝病所致的代谢紊乱,易致多脏器功能障碍甚至衰竭,并发症多,死亡率高;而微囊化肝细胞移植技术,既可阻断受体的免疫排斥反应,又保证移植的肝细胞在体内长期存活,为急性肝衰治疗提供新的治疗方法。

HE staining and prussian blue staining in all transplantation mice were done and the result of the staining was analyzed. RESULTS: The macrophages were seen in the inner of 2 subcutaneous ectopia transplantation tumor models and the kupffer cells were found in the inner of 3 subcutaneous ectopia transplantation tumor models by Prussian blue staining.

结果: Prussian blue染色皮下移植瘤组有2只瘤鼠的瘤灶内见较为聚集的单核/巨噬细胞,肝脏移植瘤组中3只瘤鼠的瘤灶内见枯否细胞;肝脏移植瘤组见7个瘤灶与正常肝组织呈明显的浸润性生长。

MethodsOf 47 rat OLTs, 20 were per-formed with conventional two-cuff technique, 27 were combined with external bile drain-age and enterostomy. In the experimental group,a self-made connector was used to rebuid in vitro bile flow bypass, and all rats were placed in self-made restraining cages for bile collection.

47例大鼠原位肝移植,其中27例采用改进术式:在传统肝移植胆道外引流的基础上,加行空肠造瘘,并在体外建立胆汁回流通路,术后通过自制的限制性大鼠笼固定大鼠以便采集胆汁;其余20例仅单纯行肝移植术。

In one study, the researchers compared results using ECD organs with what they term "extreme" ECD organs, which included either donors over age 70; donation after cardiac death, which used to be taboo because of the risk of the organ being deprived of oxygen; organs stored more than 30 hours before transplant, or kidneys in which the filtering units were scarred at least 30 percent.

在第一项研究中,研究者把用ECD器官移植的结果与"极端"ECD器官移植的结果进行了比较,这些"极端"ECD器官来自于:70岁以上的捐赠者、心脏死亡后的捐赠(以往因器官缺氧而遭到禁忌)、器官在移植前已经被保存了30小时以上、至少30%的肾单位已受到损坏。

The appropriate electric fusion parameters for nuclear transfer of porcine somatic cells were investigated using in vitro matured porcine oosytes as recipients and granulose cells as donors in this study.

本研究用体外成熟42~46 h的猪卵母细胞为核移植受体,猪颗粒细胞为核移植供体,对猪体细胞核移植的电融合参数进行了探讨。

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