查询词典 structural gene

Developmental biologists may be more emphasis on the informational concept of gene, evolutionary biologists may be more emphasis on the functional concept of gene, and molecular biologists may be more emphasis on the structural concept of gene.

发育生物学家可能会更偏重于基因的信息概念，进化生物学家可能会更偏重于基因的功能概念，分子生物学家可能会更偏重于基因的结构概念。

The research on the Na+/H+ antiporter gene from Zostera marina L. can help to find the structural and functional difference of the different plant Na+/H+ antiporter gene and help to mastering the salt-tolerance mechanisms of the Na+/H+ antiporter gene.

研究大叶藻中Na~+/H~+逆向转运蛋白基因对于了解不同植物Na~+/H~+逆向转运蛋白基因在结构与功能上的差异，以及进一步深入了解该类基因的耐盐作用机理具有重要意义。

In order to elucidate the relationship between the structural features of leginsulin gene in legume plants and their phylogenetic significance,we have cloned the cDNA sequence of leginsulin gene from radicles of broad bean via RT-PCR techniques according to the leginsulin gene sequence we previously obtained from soybean.The cloned cDNA encoded for a precursor protein consisting of the signal peptide,mature leginsulin and an additional 45 amino acids of another polypeptide.

为探明豆科植物中豆类胰岛素基因的结构特征与进化关系，在已获得大豆豆类胰岛素基因的基础上，以蚕豆种子胚根mRNA为材料，采用RT-PCR技术，克隆了蚕豆豆类胰岛素基因的cDNA序列，编码的前体多肽包括信号肽、成熟型豆类胰岛素及另一多肽的45个氨基酸残基。

Kanzawa pointed, the abdominal vertebra BMD of PTH gene individuals in BB genetype is obviously higher than those of Bb and bb genetype,so he considered that the BstBI polymorphism of PTH gene has dependability with BMD while the DraⅡpolymorphism of PTH gene has no dependablity with BMD.3 The polymorphism of estrogen receptor gene and postmenopausal osteoporosisPMOP is a metabolic bone disease existing in post-menopause femmes, as a result of these femmes\' hypofunction of ovary,ESG level drawdown and the disequilibrium of bone couple procedure,the bone resorption of osteoclast exceeds the bone formation of osteoblastic,osteopenia and bone fragility accrescence have developed,then induces fracture and so on.

Kanzawa等研究发现，BB型PTH基因人的腰椎BMD较Bb、bb型显著为高，认为PTH基因BstBⅠ多态性与BMD有相关性；但PTH基因DraⅡ多态性则与BMD无相关性。三雌激素受体基因多态性与绝经后骨质疏松绝经后骨质疏松是指绝经后妇女由于体内卵巢功能低下，雌激素水平低落，骨偶联过程失衡，破骨细胞的骨吸收大于成骨细胞的骨形成作用所导致的骨量减少，骨脆性增加，进而易于发生骨折的代谢性骨疾病。

During the postgenomics era the information about genomic sequence and gene functions provides a new foundation for evolutionary biology and ecology As the first whole-genome sequenced plant Arabidopsis thaliana and its wild relatives have played a critical role in understanding the evolution of genomics and speciation Both A halleri and A lyrata are closely related to the model species A thaliana A halleri ssp gemmifera occurs in northeastern China Japan and Taiwan; while its sister A halleri ssp halleri is mainly distributed in Europe Geographical barriers such as Tienshan Mountain Range isolate these intraspecific sisters Likewise A lyrata ssp kamchatica and ssp lyrata occur in East Asia and North America respectively Such distribution patterns seem to be consistent with allopartic speciation The comparison between ancestral and extant polymorphism by multilocus can be informative about the population genetics of speciation In this study we collected and analyzed DNA sequences of 98 genes from four wild relatives of A thaliana A halleri ssp gemmifera A halleri ssp halleri A lyrata ssp kamchatica and A lyrata ssp lyrata The ancestral states of these four species were compared to each other in terms of level of genetic variation However the ancestral species at the time of speciation were substantially more polymorphic than the extant geographical populations The observations are not fully compatible with speciation by strict allopatry At some species pairs parapatric speciation seems more reasonable in speciation of Arabidopsis The 98 gene sequences are also used for the congruence test between gene genealogy and species phylogeny Only 28 genes support the species phylogeny but there are 23 genes supports another major genealogy { lyrata} thaliana Based on the phylogenetic position change of A lyrata ssp kamchatica and Ks value for each species pair suggested the recent directional gene flow between A halleri ssp gemmifera and A lyrata ssp kamchatica

阿拉伯芥是第一个完成基因体定序的开花植物，其基因体资讯提供植物学研究的重要依据；在解析阿拉伯芥属物种的亲缘关系以及种化机制等重要的演化议题时，阿拉伯芥近缘的野生物种自然成了不可或缺的关键；跟阿拉伯芥近缘的物种包括A halleri及A lyrata，其中A halleri ssp gemmifera主要分布於中国东北、日本以及台湾，与近缘的A halleri ssp halleri其分布於欧洲隔著天山及大陆的障蔽，而A lyrata ssp kamchatica主要分布於东北亚及台湾，与分布於北美五大湖的A lyrata ssp lyrata被北极圈所分隔，这样的分布模式暗示异域种化的可能。藉由多基因分析比较祖先物种与现生物种遗传歧异度的相关可提供讯息探讨种化时期的族群遗传结构，本研究针对A halleri ssp gemmifera、A halleri ssp halleri及A lyrata ssp kamchatica、A lyrata ssp lyrata四个物种，两对互为亚种的姊妹群，以阿拉伯芥为外群进行研究，在四个物种完成98个同源基因的分子序列，利用套装软体MCMCcoal来估算祖先物种的遗传变异，亦估算现生物种的核苷酸歧异度，观察到？多物种配对中祖先物种遗传多型性大於现生物种DNA歧异度，显示异域种化模型并无法完全解释阿拉伯芥属物种的种化模式，在某些物种配对间邻域种化模式应比异域种化更为可能；在基因树与物种树的比较，98个基因片段的亲缘模式只有28个是与已知物种树一致的，有23个基因其树状图支持{ lyrata} thaliana的型式，藉由kamchatica位置的变化以及估算各物种配对间的平均同义置换率，推测在A halleri ssp gemmifera与A lyrata ssp kamchatica间具有近代的单方向基因交流。

Genetic analysis were carried out to identify powdery mildew and strip rust resistance genes in the F2 of Am6-4 amphiploid and wheat variety Jinan17. Results showed that resistances to powdery mildew and stripe rust were controlled by a single dominant gene respectively. 124 SSR primers from genome D were used for marker analysis, marker Xgwm98 150(150为下标) from the chromosome 6D was found to be linked to the new powdery mildew resistance gene with a linkage distance 20.42 cM; A special DNA band was amplified by primere xgwm33 in resistant stripe rust plants, resistance gene for stripe rust was localized on chromosome 1D, and the genetic distance between resistance gene and marker is 8.0 cM.

利用Am6-4与济南17F2分离群体进行白粉病和条锈病抗性基因的遗传分析结果证明，Am6-4中的抗白粉病和抗条锈病基因均为单显性基因；以124对D基因组SSR引物进行标记分析，引物Xgwm98在抗白粉病DNA池和单株中能扩增出特异标记带，标记与抗白粉病基因间的遗传距离为20.42cM，并将抗白粉病基因定位于6D染色体；引物Xgwm33能在抗条锈病DNA池和单株中扩增出特异标记带，标记与抗条锈病基因间的遗传距离为8.0cM，并将抗条锈病基因定位于1D染色体。

Methylation of CpG islands in the promoters induces gene silencing. The multiple tumor suppressor gene P16, located at chromosome 9p21, regulating normal proliferation of cells with a functional unit constituting of p16, cyclin D1 and pRb together. Methylation of P16 gene has been detected in several lymphocytic and plasmacytic malignancies such as lymphoma, acute lymphocytic leukemia and multiple myeloma and shows relationships with the pathogenesis of these diseases. Application of demethylation agents or arsenical to refresh the gene functions will be expected to be a new treatment for hemopoietic malignancies.

基因启动子区CpG岛甲基化常导致基因沉默。P16基因是一定位于9p21的多种肿瘤抑制基因，通过pl6INK4Acyclin D1-PRb通路维持机体细胞的有序增殖。P16基因甲基化在淋巴瘤、急性淋巴细胞性白血病、多发性骨髓瘤等多种淋巴细胞浆细胞肿瘤中被检测到，并与疾病的发生、发展存在一定关系，应用甲基化抑制因子或砷剂去甲基化治疗，恢复基因功能可望成为血液恶性肿瘤治疗的一种新手段。

Sequence structure of a cloned gene is an important factor to determine its expression level in E.coli. In this paper, we studied the expression of a fragement of HIV-1 gp120 gene and a fragement of choler toxin A subunit gene in E.coli using a new expression strategyoptimizing the gene sequence as a whole.

外源基因的序列结构是影响外源基因在大肠杆菌中表达的重要因素，我们采用基于"外源基因全序列结构优化"的新的表达策略，研究了HIV-1 gp120-801和霍乱毒素A亚单位(CTA-246)基因在大肠杆菌中的表达情况。

Recent study showed that the devitalization of DPC4 gene was present in nearly 50% of pancreatic carcinoma, which interrupted the TGF-βsignal pathway, so inactivation of DPC4 gene maybe one of the most important cause of pancreatic carcinoma. The present study was carried out to clarify the effect of DPC4 gene on human pareatic carcinoma cell line JF305, which can help us understand the growth and proliferation mechanism of pancreatic carcinoma and provide us the practical guidance on gene therapy of pancreatic carcinoma.

最新研究资料表明近一半的胰腺癌存在DPC4(deleted in pancreatic carcinoma)失活，进而使TGF-β信号传导途径中断，失去其对肿瘤细胞的抑制作用，导致细胞过度生长和增殖，因此DPC4的改变可能是胰腺癌发生、发展的重要原因之一[2]。

We can make use of chip to analysis virus gene group; construct mutation detection technique of heredity diseases and become normal detection technique of many heredity diseases; supervise the changes of cell gene expression, research pathogenic theory of virus; differentiate bacteria gene types and identify bacteria strains, provide base data for screening and supervise drug-fast gene.

利用基因芯片可加速对病毒基因组的功能分析；可建立遗传病的突变检测技术，并成为对多种遗传病的常规诊断技术；可用来监测宿主细胞基因表达的改变，研究病毒的致病机理；基因芯片还可用来对细菌基因的分型和菌种鉴定，为筛选和监测细菌的抗药性基因提供基础数据。

Sodium citrate; calcium carbonate; calcium hydroxide; potassium bicorbonate; magnesium carbonate; ferrous sulphate; Zinc sulphate; copper sulphate; manganese sulphate; potassium iodide; sodium selenite.

柠檬酸钠；碳酸钙；氢氧化钙；碳酸氢钾；碳酸镁；硫酸亚铁；硫酸锌；硫酸铜；硫酸锰；碘化钾；亚硒酸钠。

All this to say that I'm glad filmmaking hasn't become completely ironic. I can enjoy an ironic film as much as the next person, but they usually involve a message of some sort. One that's delivered in a smirkingly clever way that requires little in the way of talent.

所有这些都是说，我很高兴电影制作没有变成完全讽刺艺术，我可以和下一个人一样享受讽刺电影的乐趣，虽然他们经常会被划归到一定级别，技术方面不需要很高的才能。