查询词典 lethal dose

Missed dose: skip the missed dose and go back a daily dose. Do not double the doge the next day.

如某天忘记添加本产品，请不要双倍补偿添加，只需要加回每日的正常剂量便可。

METHODS: Total 60 male Wistar rats were randomly divided into 6 groups, i.e., normal control group , DMN model group , large dose treatment group , middle dose treatment group, small dose treatment group and Dongbao gantai treatment group. The liver fibrotic model was induced by i.p. dimethylnitrosamine for 4wk. The relative herbs were given after model establishment in each treatment group and the administration lasted for 6 weeks. Decollate to get the blood and The serum hepatofibrosis indexes, hyaluronic acid, collagen IV, pro-collagen type III and laminin were measuredwith radioimmunoassay. SOD and MDA were measured with biochemistry method. The liver pathological changes were observed in each group of rats.

将60只雄性Wistar大鼠随即机分正常对照组、模型对照组、实验大剂量组(20ml/kg/d)、实验中剂量组(10ml/kg/d)、实验小剂量组(5ml/kg/d)及东宝肝泰药物对照组；腹腔注射二甲基亚硝胺制备大鼠肝纤维化模型，连续灌胃6周，断头取血，生化检测血清SOD、MDA；放射免疫法测定血清HA、LN、PCIII及IV-C；取肝左叶做HE染色和Mallory胶原染色，观察肝病理组织学改变。

Methods The cardiac myocytes model of myocardial ischemia reperfusion injury was induced with sodium dithionite (Na2S2O4). The primary cultured cardiac myocytes of SD neonatal rats were randomized into six groups: normal group, model control group, high-dose β-asarone (25 μg/mL), middle-dose β-asarone group (12.5 μg/mL), low-dose β-asarone group (6.25 μg/mL) and medium group.

采用连二亚硫酸钠(Na2S2O4)建立心肌细胞MIRI模型，将原代培养的SD大鼠乳鼠心肌细胞分6组：正常对照组、MIRI模型组、β-细辛醚高、中、低剂量组(25， 12.5， 6.25μg/mL)、基质组。

Methods Animals were randomly and equally divided into five groups: saline control group, positive drug control group, low-dose, medium-dose and high-dose crocetin group. Animals were anesthetized with urethane (1.2 g/kg), then followed by the perfusion of aconitine (10 μg/mL) through caudal vein in rats, or of ouabain (9 μg/mL) through external jugular vain in guinea pigs in a constant velocity of 0.1 mL/min, and the emergence time of ventricular fibrillation, ventricular extrasystole, ventricular tachycanlia and cardiac arrest were then detected and recorded. The recorded time was then translated to the cumulated amount of aconitine and ouabain. Experimental arrhythmia was induced by rapid injection of 4% CaCl2 (140 mg/kg), and the emergence time, persistence time, incidence and death of arrhythmia after the administration were observed.

将实验动物随机分为生理盐水组，阳性药物对照组，藏红花酸高、中、低剂量组，SD大鼠采用1.2 g/kg乌拉坦麻醉后，从尾静脉匀速(0.1 ml/min)灌注10μg/ml乌头碱溶液，豚鼠麻醉后从颈静脉匀速(0.1 ml/min)灌注9μg/ml哇巴因溶液，观察出现室性期前收缩、室性心动过速、室颤和心脏停搏的时间，然后换算成乌头碱和哇巴因的累积量；快速推注4%氯化钙(140 mg/kg)诱导大鼠心律失常，观察给药后心律失常出现时间、持续时间、心律失常发生数及死亡数。

The energy distribution of the focused laser spot has Gaussian profile, and if the exposure dose threshold of the photoresist is less than and far away from the peak of that Gaussian curve, the linewidth will be less affected by the variation of exposure dose or exposure dose threshold, and so, will improve the linewidth stability.

准直光束经物镜会聚后光斑的能量呈近似高斯分布，当胶层的曝光量阈值远离高斯型曝光量曲线的头部时，可以弱化线宽对实际曝光量或胶层曝光量阈值等变化的敏感度，从而提高线宽的稳定度。

Objective To study the effect of helical CT scanning dose and slice thickness on lung density, and to determine whether the lung density value measured by standard dose helical CT scan can be used for low dose helical CT scan.

目的 探讨螺旋CT扫描剂量、层厚是否对肺密度有影响，以决定常规剂量螺旋CT扫描测得的肺密度值能否适用于低剂量螺旋CT。

Results: Mouse body weights were significantly lower in high and low dose groups than that of control group (P.05); Spleen index in middle dose group (P.05) and hemolysin titer in high dose group (P.01) were obviously higher than those in control group.

结果：与对照组比较，高、低剂量组小鼠体重明显下降(P.05)，中剂量组小鼠脾脏指数明显升高(P.05)，高剂量组小鼠的溶血素效价显著升高(P.01)。

RESULTS The proliferation of fibroblasts was inhibited by K102 in vitro. A dose-dependent antagonistic effect was found between K102 and bFGF. The serum levels of ALT, AST and the liver hydroxyproline level in the treated groups were lower than that in the CCl4 model group. Pathological examination showed a slight fatty degeneration and hydropic degeneration was observed in the group treated with the high dose K102, the low dose K102, and the control group.

结果体外生物活性检测：K102明显抑制成纤维细胞的生长，bFGF对K102有一定拮抗作用，且具有剂量依赖性；体内生物活性检测：治疗给药组血清ALT，AST和肝组织羟脯氨酸含量较CCl4模型组明显改善。

Methods: Gastric cancer model of nude mice were established by transplanting human gastric cancer cell line (BGC-823) into hypoderm at right armpit, and then the cancer-beating mice were divided randomly into 5 groups: model group, cyclophosphamide group, and 3 Ad treated groups (high-dose, middle-dose, and low-dose groups).

将人胃癌细胞BGC-823接种于裸鼠右侧腋皮下，建立荷瘤裸鼠模型。

If the expected positions of the minimum and maximum dose are known from a previous irradiator performance characterisation, some dosimeters could be removed from regions of average dose and replaced to form a 10 cm grid in the regions of extreme dose.

如果从先前的辐照器的特征试验得到各测量位置的最大剂量和最小剂量，一些辐射量测定器可从平均剂量的区域处移走并能在极端剂量区域里放置排列成一个10厘米格子。

Core, self psychology is psychoanalytic, but there are crucial differences in how the patient-therapist relationship is viewed.

自体心理学的核心是精神分析，但在如何看待患者-治疗师关系方面，自体心理学和精神分析有着根本性的不同。

High-performance cars brake drum production costs increase less than 10%.

高性能汽车刹车鼓的生产成本增加小于10％。