查询词典 lethal dose

Result:(1)The CTDIw in low dose group was 34.9％ of the index in conventional dose group;(2) The image quality in low dose group mostly was better,but inferior to that in conventional dose group,and all images were qualitied for diagnosing.

结果：（1）低剂量扫描组的CTDIw吸收剂量仅相当于常规剂量的34.9％；（2）低剂量组图像质量以较好为主，较常规剂量组稍差，但未出现不合格图像，不影响诊断。

Methods 72 mimic cervical radiculitis Wistar rats were divided into 4 groups randomly:moderate dose group of JZ-I,high dose group of JZ-I,Jingfukang group and control group.JZ-I of moderate dose,JZ-I of high dose,Jingfukang and water were given to the rats seperately.PGE2 was determinated by radioimmunoassay at 3,7,14 days after animal models had been made.

将72只模拟颈神经根炎Wistar大鼠随机分为四组：颈椎Ⅰ号中剂量组、颈椎Ⅰ号高剂量组、颈复康组及空白对照组，分别给予颈椎Ⅰ号中剂量、高剂量、颈复康及凉开水，于造模后3天、7天、14天，取血浆进行PGE2含量的放射免疫测定。

objective:to investigate the influence of soybean isoflavones on the antioxidative effect and improving the ability of study and memory in climacteric rats.methods:forty-eight female sd climacteric rats were randomly divided into 4 groups with one control group and the other low,medium and high dose groups,which were given soybean isoflavones 0 mg/kg.bw,42 mg/kg.bw,83 mg/kg.bw and 249 mg/kg.bw by superalimentation daily for 60 days respectively.the levels of sod,gsh-px and mda in serum were measured,and the ability of study and memory in each group was deterimined by adopting the law of diving platform.results:the content of serum mda in medium and high dose groups was lower than that in control group.the activity of serum gsh-px im medium and high dose groups was significantly increased,so was the activity of serum sod in low,medium and high dose groups.conclusion:soybean isoflavones do have the obvious effect of antioxidation,and improve the ability of study and memory effectively in female sd climacteric rats.

目的：观察大豆异黄酮对更年期雌性sd大鼠抗氧化作用及学习记忆的影响。方法：选用健康更年期雌性sd大鼠，随机分成空白对照组和低、中、高剂量4组。空白对照组给予蒸馏水，实验组每日分别灌服42、83、249 mg/kg剂量的大豆异黄酮，连续60d。第60d取血测定血清过氧化脂质丙二醛含量、超氧化物歧化酶活力、谷胱甘肽过氧化物酶活力，用跳台实验方法测定大鼠学习记忆能力。结果：与空白对照组比较，中、高剂量组大鼠血清mda含量显著降低，低、中、高剂量组血清sod活力明显升高，中、高剂量组血清gsh-px活力明显升高。结论：大豆异黄酮具有明显的抗氧化作用，并有效提高更年期雌性sd大鼠的学习记忆能力。

Results:(1) The rats produced amphetamine CPP after treated with 2 mgkg^(-1) amphetamine for 4 days. Ketamine and low, middle, high dose rhynchophylline all could eliminate the CPP effect, and the effect of rhychophylline was increased in a dose-dependent manner. Rhychophylline itself could not induce CPP in normal rats.(2) When compared with normal rats, the NR2B expression in nucleus accubens and amygdaloid of the model rats was obviously increased. Ketamine and middle, high dose rhynchophylline could decrease NR2B expression induced by amphetamine, while low dose rhynchophylline did not affect NR2B expression. Rhynchophylline had no effect on RN2B expression in normal rats.

结果：(1)建立了苯丙胺（2mgkg^(-1)，连续4d）诱导的位置偏爱模型，氯胺酮及钩藤碱低、中、高剂量均可消除苯丙胺诱导的位置偏爱效应，随钩藤碱剂量增加其效应加强，且本身无精神依赖性；(2)苯丙胺模型组大鼠伏核和杏仁核NR2B蛋白表达增加，氯胺酮及钩藤碱中、高剂量抑制NR2B表达，低剂量及本身对NR2B表达无影响。

The point doses at the inferior beam edge for the two energies were 31.2% and 32.4%, respectively. There were 47-54% dose increase for superior beam edge and 37.6-35.2% dose decrease for inferior beam edge, as compared to the 50% field edge dose with the static dose distribution. There were 8.5 and 7.5 mm range increase for superior beam penumbras and 5.5 and 4.5 mm range increase for inferior beam penumbras, an important result corresponding to treatment volume.

结果：以正常人的平均值为例，在一个照射时距内，使用6 MV及18 MV光子射束， 10X10cm2照野10cm深度之中心轴下，照野上缘的剂量，分别为照野中心点剂量的73.5 %及77.2 %，照野下缘的剂量则分别为中心点剂量的31.2 %及 32.4 %，此剂量反映出因治疗中的呼吸位移，造成照野上缘较照野中心点有47 –54 %的剂量增加，及照野下缘有37.6 %- 35.2 %的剂量减少，相对照於静止态下照野边缘为中心点50 %剂量的状态。

Methods : We gave 0, 1, 2, 3, 4 times low dose total-body irradiation to control group (No. 1 group) and experiment group (No. 2, 3,4,5 group) respectively with γ irradiation .Each dose is 0. 1GY and dose rate is 1.28 cGY/min. The interval of each irradiation is 48 hours . Six hours after every group finished their own total dose , we kill the rats and get their thyme .

采用γ射线分别对对照组(1组)和实验组(2、3、4、5组)给予0、1、2、3、4次低剂量全身照射，单次剂量0.1GY，剂量率为1.28cGY／min，每次照射间隔时间48小时，各组在完成照射总剂量后6小时处死取胸腺，采用双参数直接免疫荧光流式细胞术，检测大鼠低剂量全身照射后胸腺细胞CD4、CD8、CD3~+T细胞的表达情况以及CD4／CD8的变化。

A usual starting dose of 10 mg given three or four times daily increasing if necessary to a maximum of 20 mg given five times daily has been used. 2 However, some workers have recommended limiting the dose to 80 mg daily because of the increased risk of seizures with higher doses. 3 Adverse effects appear to be mainly mild and dose related, 1 although there is a report of cardiac arrest following toxicity. 4 Most patients have some form of paraesthesia up to 60 minutes after a dose. 1-3 Amifampridine can produce mild excitatory effects and some patients may have difficulty in sleeping.

阿通常开始10毫克剂量三，每天4次，如有需要，增加了20毫克，最高给予5倍每天已被使用。2然而，有些工人建议限制在80毫克剂量的增加，因为日常的风险与高剂量的发作。3不良影响似乎主要是轻微和剂量有关，1虽然有心脏停止跳动后中毒的报告。4大多数患者有某种程度的感觉异常形式的最多60分钟后剂量。1-3 Amifampridine可产生轻微的兴奋作用，有些病人可能有失眠。

The number of chickens in each group is 16 for SPF chicken At 4 weeks of age, chickens were eye-drop immunized with the recommended dose of commercial IBV vaccine, or vaccinated intradermally via wing with 5×106 PFU rFPV-IBVS1 or 5×106 PFU S-FPV-017. Four weeks after vaccination, chickens in all groups were challenged by bronchitis injection with a lethal dose (0.2ml 8.5EID50/0.1ml) of IBV XJ3 strain After challenge, chickens immunized with rFPV-IBVS1 and commercial IBV vaccine were all protected from death; the result indicated that rFPV-IBVS1 can protect chickens from the infection of IBV.

攻毒后的结果显示所有含rFPV-IBVS1免疫组的SPF鸡均100%保护而免于死亡；IBV弱毒疫苗免疫的SPF鸡也获100%保护，免疫以后的抗体跟踪检测证明rFPV-IBVS1诱导的抗IBV抗体水平低于IBV弱毒疫苗免疫组；攻毒后进行的IBV分离和PCR检测结果表明IBV弱毒疫苗免疫的SPF鸡能够更好地阻止攻击强毒的感染。

Brain ischemic preconditioning is that transient ischemia in sublethal dose will result in tolerance to the following ischemia in lethal dose for long time.

脑缺血预处理即给予短暂亚致死量缺血可对随后的长时间致死性缺血损伤产生耐受。

The local injection of trypsin can be used in clinical practice as a new and effective therapy for snakebite.Our experiments indicate that when a lethal dose of crotalinae snake venom was injected into mice subcutaneously, survival rate increased significantly if a dose of trypin had been injected locally and promptly.

本文提供了一种局部注射胰蛋白酶治疗蛇伤的方法，在给小白鼠皮下注射致死剂量的竹叶青蛇毒后，立即注射胰蛋白酶可提高存活率68％，注射蝮蛇毒后，立即注射胰蛋白酶可提高存活率67％，注射尖吻蝮蛇毒后立即注射胰蛋白酶可提高存活率57％。

The statistical analysis of this large set of mutations has led us to propose a diagnostic strategy that should help with the molecular work-up of optic neuropathies.

这一大系列基因突变的统计学分析引导我们提出一个诊断策略，可以帮助我们对视神经病变进行分子学的诊断检查。

The results show that the pipe grouting changes the mechanical parameters of surrounding rocks to achieve the security of engineering objectives by reinforcing surrounding rocks and bolcking the water.

研究表明：小导管注浆一方面改变了围岩的力学参数，另一方面利用浆液的固结特性可以实现堵水和加固围岩的工程目标，使隧道在开挖过程中的安全得到保障。