查询词典 bud mutation

Sequencing and mutation detection in collaboration with Dr. Dunlap have localized prd-4 mutation.

和美国 Jay Dunlap合作进行了测序和突变分析，获得了生物钟prd-4基因。

Objective To investigate the FECH gene mutation in a Chinese family with erythropoietic protoporphyria, to explore the relationship between gene mutation and clinical manifestations so as to establish a basis for the genetic diagnosis and treatment of erythropoietic protoporphyria.

目的 对一红细胞生成性原卟啉病家系进行基因突变研究，探讨基因突变与临床表现的关系，为进一步开展基因诊断和基因治疗奠定基础。

A novel mutation in the donor splice site of intron 1 of FECH gene is first reported in a Chinese family with EPP; this mutation may lead to a deficiency of FECH gene and serve as a molecular basis of development of erythropoietic protoporphyria.

报道一FECH基因第1内含子供体剪接位点的新突变，该突变可能引发FECH基因缺陷，是EPP家系中患者发病的分子基础。

Chemical mutagenesis can effectively create many new peanut genotypes. And appropriateconditions of induced mutation can increase mutation efficiency and develop peanut germless resources well.

化学诱变能有效的创造各种突变体，确定诱变的适宜条件能提高诱变效率，更好地拓展花生种质资源。

To study genetic mutations of methylenetetrahydrofolate reductase C677T and cystathioinine-β-synthase T833C related to homocysteine metabolism in patients with ischemic stroke, the MTHFR gene C677T gene mutation and the CBS T833C gene mutation were detected by PCR-RFLP or ARMS method in 74 patients with ischemic stroke and 83 normal people for control. Results showed that the frequencies of MTHFR genet homogenetic type(2.7%), heterogenetic type(51.4%) and T allele(28.4%) in ischemic group were higher than those in control group(1.2%, 39.8% and 21.1%, respectively).

为研究同型半胱氨酸代谢相关酶亚甲基四氢叶酸还原酶基因C677T和胱硫醚-β合成酶基因T833C位点碱基突变与缺血性脑卒中的关系，对74例缺血性脑卒中患者和83例健康对照者，采用聚合酶链反应-限制性片段长度多态性技术检测MTHFR基因C677T基因型，用扩增阻滞突变体系法检测CBS基因T833C突变。

Moreover,7449, a novel homoplasmic mutation in the tRNA-Ser gene, was found to co-exist with 1555 mutation in two maternal members.

另外，新发现一个线粒体DNA突变--7449，但该突变仅在2名母系成员中存在。

Results Fourteen individuals from two pedigrees carried homoplasmic 1555G mutation. Seven sporadic patients and the five mothers did not have 1555G mutation.

结果 两个家系的14份样品为1555G点突变阳性，散发病例及部分亲属的12份样品全部为1555G点突变阴性。

The D-loop region was found to be a hot spot for somatic mutation in mtDNA of the tumors. The results revealed that 45.7 %(16/35) of the HCCs carried somatic mutation in the D-loop region, and the most mutations are homoplasmy.

过去的研究显示：粒线体DNA D-loop 区域是发生体突变的好发点，本论文的结果显示有45.7 %(16/35) HCC含有D-loop 区域体突变且多为同质性。

mitochondrial dnais the only inheritant substance except for the nuclear dna in a euˉkaryon cell,which is related to the oxidative phosphorylation of a cell.mitochondrial dna is the important target of carcinogens and is vulnerable because of its structure and function.the mutation of mtdna could reduce the nomal respitation and release large quantities of ros,whichincrease the danger of cancer happening.so,mtdna has been thought to be involved in carcinogenesis and recently more and more studies in this aspect have comeout.in this paˉper,we review the researches for relationship among mtdna mutation and tumors in digestion system,woman system,head and neck,urinary systemand blood system.

线粒体dna（mitochondrial dna，mt dna）是真核细胞中唯一存在的独立于核dna之外的遗传物质，与细胞的氧化磷酸化功能密切相关。mtdna自身的结构和功能特点决定了它是致癌物作用的重要靶点，易受致癌因素的损伤而发生突变。mtdna的突变可削弱正常的呼吸功能，释放高水平的活性氧，进而增加肿瘤发生的危险性，所以mtdna被认为与肿瘤发生有密切关系。近年来，这方面的研究越来越多，本文现就mtdna突变与消化系统肿瘤、妇科肿瘤、头颈部肿瘤、泌尿系统肿瘤等实体瘤以及血液系统恶性肿瘤之间的关系作一简单的综述。

Objective To analyze the role of p16 gene mutation in acute lymphoblastic leukemia genesis and mechanism of p16 gene mutation.

目的 探讨p16基因突变在白血病发生中的作用及基因突变的机制。

The receding calculations and experiment analyses in this subject are built on the blood cast of pig tongue.

本研究课题的前期工作是采用猪舌血管铸型模拟人舌而进行的数值计算与实验分析。

"Each human infection constitutes an opportunity for genetic modification of the virus through reassortment, mutation, or both...."

&每一次人类的感染都暗藏着一次基因修改的机会，无论是通过病毒的整合、突变或者兼而有之。。。。&