查询词典 IL

Among the most common excretive cytokines, increasing of GRO, IL-6, IL-8 and TIMP2 might be related to drug-resistance of ADM and CBPDA in ovarian cancer cell, while IL-6 and IL-8 might also be related with drug resistance of TAXOL and VP16. The different types of ovarian cancer cell might have roughly similar excretive cytokines-induced mechanism of drug resistance.

在常见分泌型细胞因子中，GRO，IL-6，IL-8和TIMP-2升高与一线化疗药ADM和CBPDA耐药性相关，IL-6，IL-8与二线化疗药TAXOL，VP16耐药性相关，不同来源的卵巢癌细胞分泌型蛋白作用机制可能存在共同的上述几种蛋白参与的调节体系。

RESULTS Plasma levels of IL-8, IL-10, MMP-9 were higher at 1 h, 4 h and 6 h aortic dclamping off in continuous ventilation and the nonventilation group, and IL-8 level were significantly higher in nonventilation group compared with ventilation group, IL-10 levels were significantly higher in the ventilation group than nonventilation group after 1 h and 4 h, 6 h, TIMP-1 levels were significantly higher in the ventilation group than that in nonventilation group after 1 h and 4 h.

TIMP-1的血浆水平在术后持续升高，在术后1 h和4 h持续通气组较非通气组明显增高。血浆中TXB2水平在主动脉开放后1 h、4 h和6 h明显高于术前水平，持续通气组较非通气组水平明显降低。支气管肺泡灌洗液中IL-8、IL-10、MMP-9和TXB2 水平在主动脉开放后4 h较术前明显升高。

Objective: To explore the changes of serum IL-6, IL-12 levels in patients with hepatitis C and the role of IL-6, IL-12 in pathogenesy of hepatitis C.

目的：探讨丙型肝炎患者血清IL-6、IL-12水平的变化以及在丙型肝炎发病机制中的作用。

Changes in IL-2/IL-2R system in 25 patients with thyrotoxic Graves disease and 20 eu-thyroids were investigated and compared with those of 15 normal controls. The thyrotoxic patients showed a high concentration of serum sIL-2R and a large amount of circulating IL-2R-α- cells but a decreased production of IL-2 by PBMC. However, these abnormalities had a tendency to become normal with improvement of the disease.

Graves病的发生是环境、遗传和免疫等多种因素综合作用的结果＊淋巴细胞的免疫调节异常是其中的一个重要原因，而白细胞介素-2（IL-2）及其受体在维持正常T细胞功能和兔疫调节方面发挥关键作用。

TO Acute Leukemia, the level of IL-1 J3 ,IL-6 and TNF-a rise significant in the stage of Yingfen Syndrome, and significant higher than that of the Weifen and Qinfen stge, when it comes to IL-10, the level of its declines rapidly ,but the level of IFN-r changes a little.The serum level of IL-6 of Yingfen Syndrome of Acute Leukemia is higher than that of the unacute one.

急性白血病发展到营分证阶段时，IL一1日、IL一6、TNF--a 显著升高，高于卫分证、气分证，1L一10则显著下降，而IFN一y无显著变化；急性白血病营分证血清中工L一6的表达水平高于非急性白血病营分证，而工L一10则相反。

Methods Detected IL-2, IL-5, IL-10 and EOS of 60 cases in patients with eczema and 40 cases health controls by ABC-ELISA and detect counting method.Analyzed the data with the SPSS 11.5 software. Results The IL-2 in patients with eczema wase lower than that of the health groups.

采用双抗夹心法和直接计数法分别检测湿疹患者60例和正常健康体检者40例的血清IL-2，IL-5，IL-10和血液中EOS的水平，应用SPSS11.5统计软件包对结果作统计学分析。

The histopathologic changes included lymphocyte and monocyte infiltration,hyperplasia of synovial cells and small vessels,interstitial fibrosis,hyaline degeneration and cartilaginous metaplasia.The immunohistochemical observations showed that the high expressions of IL-1 and IL-6 were significantly different between the pathologic plicae and the control groups（P＜0.01）.The positive expressions of IL-1 and IL-6 were the synovial cells and monocyt-lymph cells in the pathologic synovial plicae.The positive expressions of MMP-1 and TIMP-1 have significant difference between the experiment and control group（P＜0.01,P＜0.05）.The expression of MMP-1 was positive in synovial lining cell,monocyte,fibroblast,endothelial cell in small vessel and chondrocyte.The TIMP-1 expression was detected in the synovial lining cells and a small quantity fibroblast.

结果 正常滑膜皱襞和病理性滑膜皱襞在滑膜细胞增生及小血管增生、间质纤维化及玻璃样变、软骨化生组织学改变方面，差异均有显著性（P＜0.01）；IL-1、IL-6在病理性滑膜皱襞内的增生滑膜细胞、单核及淋巴细胞和在正常滑膜皱襞内的表达差异均有显著性（P＜0.01）； MMP-1、TIMP-1在病理性滑膜皱襞和正常皱襞内的阳性表达，差异具有显著性（P＜0.01，P＜0.05），MMP-1在增生滑膜衬里层细胞、单核和纤维母细胞、血管内皮细胞和软骨化生的软骨细胞呈阳性表达；TIMP-1只在滑膜衬里层细胞和少量纤维母细胞有表达。

Results IL-8 antigen staining was observed predominantly in the acidophilic and the epithelium cells in the nasal polyps, and immunoreactive IL-8 was distributed widely in the cell plasm of these cells, and IL-8 antigen staining was barely observed in control.

结果 鼻息肉中IL-8免疫阳性物质存在且主要分布在鼻息肉上皮层和嗜酸性粒细胞的细胞浆内；对照组中，上皮层细胞浆有少量的IL-8免疫阳性颗粒着色。

Investigations in vivo and in vitro have elucidated the following: IL-2 and IL-2R have been detected in the brain; IL-2 promotes survival and neurite extension of cultured neurons, stimulates oligodendrocyte proliferation and maturation, affects the hypothalamic-pituitary function and produces behavioral and electrocorticogram spectrum changes.

研究表明IL-2在脑中主要存在于海马、下丘脑、小脑、前额皮层、纹状体、膈以及蓝斑等脑区。

Results: All rats in experiment group devloped CAG at the end of 12 weeks with the following Pathological changes of CAG such as thin mucosa layer, thick muscle layer, decreased glandes, soakaging inflammation cells in microscope and with the time prolonging, the atrophy of gastric mucosa became more serious; In normal control group and normal feeding group, the IL-6 and IL-8 content in blood serum are the same at every time point; In experiment group, IL-6 became increased from 4wk and kept high level from 4wk to l2wk and had significant difference compared with normal controls.

结果：灌胃至12wk时出现胃粘膜层变薄，固有层腺体减少，固有层纤维结缔组织增生，粘膜肌层明显增生，慢性炎细胞浸润等萎缩性胃炎表现，随著热盐水灌胃时间的延长，32wk胃粘膜萎缩程度明显加重；正常对照组和正常餵养组大鼠各时间点血清IL-6，IL-8含量基本相同。

Foods high in this vitamin include oily fish such as salmon, tuna and, and fish liver oils.

维生素D含量高的食物包括诸如大麻哈鱼、金枪鱼和鲭鱼之类的油鱼以及鱼肝油。

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