查询词典 IL

Newly diagnosed diabetes patients had a defect of IL-4,IL-2 secretion and an elevation of IL-1 β.TH1 bias exited in type 1 diabetic patients.The positive lineal relation between fasting insulin and IL-1 β and between fasting C-peptide and IL-12 exited.TNF-α elevated in HLA-DQB1*0301 carrier compared with non-carrier.

新诊断1型糖尿病病人存在IL-4、IL-2低下及IL-1β的分泌增高；1型糖尿病病人存在TH1优势；IL-12与IL-4正相关，表明了它们对TH1、TH2细胞的调节关系；CK与HbA1c无显著相关性；HLA-DQB1*0201携带者TNF-α较高。

In situ hybridization was used to localize IL-4, IL-6, IL-1β, IL-2, IFN-γ and TNF-α mRNAs in abomasum of the negative control group, challenged control group, vaccinated-challenged group and vaccinated-unchallenged group goats immunized with rHco-GAL-f/m, and the numbers of cytokine mRNA(superscript +) cells in each group were also analyzed.

用rHco-GAL-f/m免疫山羊，通过原位杂交法对阴性对照组、攻虫对照组、免疫攻虫组和免疫不攻虫组山羊皱胃中白介素－1β(IL-1β)、白介素－2(IL-2)、白介素－4(IL-4)、白介素－6(IL-6)、干扰素－γ和肿瘤坏死因子－αmRNA转录进行定位，并对上述细胞因子阳性反应细胞数量进行分析。

Methods Fifteen dogs were randomly divided into 3 groups. Group A acted as the control group without CPB; group B and group C were subjected to cardiopulmonary bypass and crossclamping the aorta for 90 min. MP or saline was injected intravenously before surgery. Plasma levels of IL-1β、TNF-α、IL-6、IL-8 and IL-10 were measured at the following time points: before MP or saline were administered, aortic declamping, 30 min and 90 min, after aortic declamping. Immediately after the animals was killed, pulmonary arterial rings were obtained and mounted in organ chamber for assessment of endothelial function with endothelium-dependent or non-endothelium-dependent studies.

健康家犬15只，随机分为3组，A组：不进行CPB，作为非体外对照组；B组：麻醉后注射生理盐水10mL，常规全麻和CPB，主动脉阻断90min；C组：麻醉后静脉给予甲泼尼龙5mg/kg，其余处理同B组。B、C组分别在手术前及主动脉开放前、开放后30min和90min 4个时间点采动脉血，放免法测定血浆白介素－1β(IL-1β)、肿瘤坏死因子－α、白介素－6(IL-6)、白介素－8(IL-8)和白介素－10(IL-10)水平；手术结束时，A、B、C 3组均取右肺动脉段，固定于张力传感器，测定血管环内皮依赖性和非内皮依赖性扩张能力的变化。

Methods: ELISA was used to test the levels of VCAM-1,IL-1β,IL-2,IL-4 and IL-10 in serum from 33 patients with NPC and 7 patients with chronic nasopharyngitis.

用ELISA方法检测34例鼻咽癌患者和13例慢性鼻咽炎患者血清标本中VCAM-1、IL-1β、IL-2、IL-4和IL-10浓度。

IL-1 is elevated in tissue homogenates of temporal lobe and in cerebrospinal fluid from patients with AD. In Alzheimer patients activated immunoreactive IL-1+microglia are increased sixfold over those presenting in age matched controls and the activated IL-1+ microglia are involved in the evolution of diffuse plaque to the diagnostic neuritic plaque. IL-1 is produced by astrocytes and microglia which are components of senile plaques and induced astroglia proliferation.

AD患者颞叶脑组织及脑脊液中发现IL-1含量增高，并且IL-1免疫反应阳性的小胶质细胞比同龄的对照组高6倍，IL-1免疫反应阳性的小胶质细胞与弥散性淀粉样沉淀斑块发展成为具有诊断意义的神经纤维斑块有关。

Results Combined treatment with IL-12 and IL-2 could significantly delayed the peak of parasitemia and prolonged survival time of the P.berghei infected mice when compared with the treatment with IL-12 or IL-2 alone.

结果 IL-12联合IL-2处理组可较单独IL-12或单独IL-2及感染对照组显著推迟原虫血症达峰值的时间与明显延长小鼠的存活时间，IL-12或联合IL-2组小鼠在原虫血症达30%时开始死亡，而单独IL-2或感染对照组小鼠在原虫血症低于13%时已全部死亡。

Methods 27 pigs were divided randomly into three groups(group C, group MODS, group HVHF).Major organs function were monitored. Erythrocyte natural immune adherence function and erythrocyte chemokine receptor were detected by rosette formation test and enzyme-linked immunosorbent assay, respectively. Plasma and ultrafiltrate concentrations of TNF α IL-1β IL-6 IL-8 IL-10 were measured.

方法27头猪随机分为对照组、MODS组及HVHF组，监测各主要脏器功能，测定红细胞CR1天然免疫粘附能力、红细胞趋化因子受体结合活性及血浆和超滤液中TNFα、IL-1β、IL-6、IL-8、IL-10浓度变化。

Results: T cell anergy was antigen-specific. The state of T cell anergy can be reversed by PHA, CD3 mAb and PMA plus A23187. IL-2 can prevent the induction of T cell anergy, but it can not reverse the state of un-responsiveness. IL-2 and IFN mRNA can not express in anergic T cells. In contrast, IL-4 and IL-10 mRNA were detectable.

结果：T细胞无能为抗原特异性的，多克隆激活剂PHA、CD3单抗和PMA+A23187可以恢复无能T细胞的活性；IL-2可以阻止T细胞无能的形成，但不能逆转其耐受状态；无能T细胞IL2和IFN mRNA是关闭的，而IL-4和IL-10 mRNA则是开放的。

Transgenic expression of IL-1ra and degree of audiogenic seizure of P77PMC rats were observed after infection with pHSV-IL-1ra virus (〓 virus particles) by i. c. v injection and hippocampus injection. Results show: 1. Overexpression of IL-1ra by pHSV-IL-1ra significantly inhibited seizure attacks of P77PMC rat.

实验结果提示IL-1β可导致神经细胞NMDAR mRNA表达及受体活性增加，从而使其兴奋性增高；脑中内源性IL-1系统的异常很可能是形成P77PMC遗传癫痫易感大鼠惊厥易感性的重要因素之一；我们首次构建并鉴定了pHSV-IL-lra重组质粒，并成功地进行了脑内基因转移，使P77PMC大鼠的惊厥程度明显降低。

Results: IL-8 protein was located in the epithelium of viii. The expression of IL-8 was significantly increased in RSA group than that in the control group. Positive IL-8 cells was shown in decidua of RSA group, and its IL-8 level was higher than that in the control group. By hematoxylin-eosin staining. trophoblastic layer was found to get thinner, cells of trophoblastic layer denatured or necrotized, and turned acidophily, and the fibration of villous axis increased in RSA; decidual cells lost connection, a part of decidual cells appeared cytoclasis and turned more acidophilic, and nuclei disappeared in RSA.

结果：在绒毛组织中，IL-8蛋白定位于绒毛上皮细胞的细胞质内，且病例组的表达明显高于对照组；在蜕膜组织中；病例组蜕膜细胞的胞质内可见IL-8蛋白表达，且高于对照组；H-E染色可见病例组绒毛组织的滋养层变薄，细胞变性甚至坏死、嗜酸性增强，绒毛中轴纤维化程度增强；蜕膜组织中蜕膜细胞失去细胞间连接，部分蜕膜细胞解体、核消失。

Objective:To compare the response control and attention of Schizophrenic patients with that of the healthy controls by Integrated Visual and Auditorycontinuous performance test. To quantitate the impairment of cognitive function in patients, and to explore the relationship between cognitive function and the severity of the disorder.

目的：探讨精神分裂症病人在IVA持续操作测试中的反应控制能力、注意力等，并与健康人进行比较，从而量化精神分裂症病人的认知功能损害，并进一步探讨其认知功能与疾病严重程度的关系。

Main effective factors including subcooling degree, mechanical vibration, gas hydrate reformation, environment temperature, noncondensing gas and surfactant are analyzed.

指出过冷度、机械振动、重复生成水合物、环境温度、不凝性气体、添加剂是影响气体水合物生成的主要因素，还对R152a水合物的放冷进行了实验研究。