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Four aspects of research achievements include:(1)several imaging correction methods and strained estimation methods for biological tissues elasticity imaging were investigated as well as elasticity reconstruction and phantom, in vitro and in vivo elasticity imaging experiments;(2)in the fields of biological microsystem and perfusion evaluation for microvascular system, three kinds of microbubbles whose shell are albumin, sugar ester and surfactant respectively were designed and produced, then the methods to estimate the thickness of their shells were presented, moreover, the interacting mechanism of ultrasound contrast agents and tissues, as well as protein drug delivery under the condition of ultrasound sonification were studied in the molecular level;(3) At the aspect of high intensity focused ultrasound therapy system, we designed and constructed the 256-element HIFU transducers using 1-3 composite materials. And furthermore we developed the integrated HIFU system with 256-element HIFU transducers. And we made preliminary and important progresses in the research of HIFU bioeffect, lesion estimation, techniques of monitoring and imaging and characterizing of structure of HIFU transducer;(4)The real-time method of voice source regeneration based on compensative regulation of physiological parameters was investigated in the field of medical rehabilitation. We addressed the physiology and biophysics of vocalization, modeled voice source regeneration based on compensative regulation mechanism, and put forward an integrated evaluation about the speech rehabilitation and the regenerated voice source; Sixty-one archived journal papers were published, as well as ten in international journals, and eighteen publications were embodied by SCI.

中文摘要：成果包括：（1）在生物组织弹性成像方面，研究了多种图像校正方法和应变估计方法，进行了弹性重构和仿体、离体及在体超声弹性成像实验研究；（2）在生物微系统和微血管血流灌注成像方面，制备了三种不同包膜超声造影微泡，研究了纳米包膜厚度检测与估计方法以及不同纳米包膜造影微泡断裂与药物释放机制，并在分子层次上开展了超声与生物组织相互作用机制以及蛋白质药物超声乳化微囊包裹的研究；（3）在阵列式高强聚焦超声治疗与监控成像技术方面，设计制作了新的HIFU换能器，解决了256阵元单焦点和多焦点合成HIFU治疗系统关键技术问题，并在HIFU生物效应与创伤性评价方法、HIFU过程监控成像技术和薄层复合结构与HIFU 换能器界面特性评价等方面的研究取得了初步而重要的进展，具有重要应用前景；（4）在语音听觉系统特别是嗓音康复方面，研究了基于发声系统补偿调节机制的实时多模式嗓音源再生方法和发声生理，建立基于神经、肌肉和空气动力系统的综合补偿调节模型，提出了相应的评价系统。

For Southwestern Margin of Aqikekule Lake ophiolite, their field geological, petrological, minerological, petrochemical and geochemical characteristics show that:① it outcropped as tectonic slices along the near west-to-east strike Kunzhong fault and is composed of metamorphic perodotties, cumulates and volcanic rocks, in which, chromites are distributed in the upper part of metamorphic peridotites as pods, or in the lower part of cumulates as near-strata;② metamorphic peridotites include serpentinites, chromite-bearing serpentinites, chlorite-epidote schists and chromitites, of which, chromitites have nodular and orbicular structure, and cumulates include pyroxenits, serpentinites, chromite-bearing serpentinites, chromites and metamorphically mafic rocks and only basalts are seen in volcanic rocks;③ Cr# of chromites suggest that they formed in the SSZ and Al〓O〓 and TiO〓 of metamorphic peridotites also suggest SSZ environment;④ metamorphic peridotites have V type and enriched LREE patterns, cumulates have from strongly depleted LREE, flat REE to enriched LREE patterns with universally striking positive Eu anomalies and basalts show flat REE or slight enriched LREE patterns with no Eu anomalies;⑤ trace element and Sm-Nd isotope characteristics of metamorphic peridotites imply their strikingly heterogeneous mantle character ε〓(t+4.39～+26.20 and later Nb, Ta fertilization;⑥ trace element characteristics of basalts and their tectonic diagrams show they probably formed in the rifted island arc or back-arc basin environment.

对阿其克库勒湖西南缘蛇绿岩，野外地质、岩石学、矿物学、岩石化学以及地球化学等特征表明：①该蛇绿岩以近东西向、沿昆中断裂呈构造岩片出露，由变质橄榄岩、堆晶岩和火山岩三个单元组成，其中见铬铁岩呈豆荚状产于变质橄榄岩的上部，或呈似层状产于堆晶岩的下部；②变质橄榄岩包括蛇纹岩、含铬铁矿蛇纹岩、绿帘绿泥片岩和铬铁岩等类型，其中，豆荚状铬铁矿具有结核状构造和球状构造，堆晶岩包括辉石岩、蛇纹岩、含铬铁矿蛇纹岩、铬铁岩和变质基性岩等类型，火山岩仅见玄武岩；③铬铁矿的Cr#表明其形成在俯冲带，变质橄榄岩的Al〓O〓和TiO〓成分也指示了SSZ环境；④变质橄榄岩的稀土配分型式见V型和LREE富集型两种型式，堆晶岩表现出从LREE强烈亏损、REE平坦分布到LREE富集的配分特征，并且普遍具有醒目的正Eu异常，玄武岩的稀土配分型式表现为平坦型或LREE略富集，无Eu异常；⑤变质橄榄岩的微量元素及Sm-Nd同位素特征指示了其地幔的显著不均一性ε〓(t为+4.39～+26.20以及Nb、Ta在后期的富集；⑥玄武岩的微量元素特征及构造图解表明其可能形成在裂谷岛弧或不成熟的弧后盆地环境。

Single factor experiments were done with the factors including the width of protrusion and the trolley's velocity, which showed that the surface frictional coefficient decreases with the width of protrusion increasing, and doesn't change with the trolley's velocity changing, which was consistent with the results of the orthogonal experiment. A theoretical model of the horizontal projection of a corrugated bionic surface's contact area was built, which showed that the contact area's horizontal projection decreases with width and interval increasing respectively and that the ratio of the contact area's horizontal projection and the vertical load decreases with the vertical load increasing. It indicated that the surface frictional coefficient decreases with the above three factors increasing respectively. Finite element modeling and analysis of interactions of a plate and soils was done using ANSYS, which showed that the plate frictional coefficient is little relative to soil elastic modulus and decreases with vertical surface pressure and that trolley's pull and vertical displacement of bionic surface's control pilot keep constant almost during the plate being pulled. Finite element modeling and analysis of interactions of a corrugated bionic surface and soils was done using ANSYS, which showed that surface frictional coefficient is little relative to soil elastic modulus and decreases with bionic surface's structural parameters and vertical pressure increasing. However, the three factors all didn't affect the surface frictional coefficient remarkably on the condition of 90% dependability. For the first time, bionic surfaces were applied to screw piles, which formed bionic screw piles, and the contrast experiments showed the bionic screw pile had certain resistance-decreasing effects.

建立了波纹型仿生曲面与土壤的接触面积的水平投影的理论模型，表明接触面积的水平投影A随着波纹型仿生曲面突起宽度、两相邻突起间距的增大而减小，接触面积的水平投影与波纹型仿生曲面表面垂直载荷之比随着波纹型仿生曲面表面垂直载荷的增大而减小，进而得出仿生曲面摩擦系数随着波纹型仿生曲面突起宽度、两相邻突起间距以及表面垂直载荷的增大而减小；利用ANSYS软件对平板与土壤的相互作用进行了有限元建模与分析，表明平板摩擦系数与土壤弹性模量关系不大，而随着表面垂直载荷的增大而减小；平板牵引过程中台车牵引力和仿生曲面控制节点垂直方向位移基本保持不变；利用ANSYS软件对波纹型仿生曲面与土壤的相互作用进行了有限元建模与分析，表明波纹型仿生曲面系数在一定范围内基本不受土壤弹性模量的影响，随着波纹型仿生曲面突起宽度、两相邻突起间距以及表面垂直载荷的增大而减小，但在可信度为90％的前提下，三个因素影响都不显著；首次将波纹型仿生曲面应用于与土壤作用方式以挤压为主的螺旋桩，形成仿生螺旋桩，并与普通螺旋桩进行了沉桩对比试验，表明波纹型仿生曲面应用于螺旋桩桩体表面具有明显的降阻作用。

Write an opera about and opera is the only art form that is really worth a damn and I was wishing I had an opera in me not to write but to live.It was a cold and snowy night so I had the Dark Horse almost to myself except for one woman at the bar who had the barkeep bring me a drink only it was a shot of JD and not the stuff I was drinking and I took it and raised it to her and drank it down and she came and sat across from me and she said,"Pain—has an Element of Blank—" just like that with the capital letters and the dashes and she was wearing a black velvet dress that wasn't even remotely sexy with its white lace collar around her throat and the brooch fastened at her collarbone just like a padlock so I told her,"And blank — has an element of pain," but I couldn't manage the capital letters.

我在黑马里坐了20分钟，要喝完冰镇堪蓓莉开胃酒因为我恨堪蓓莉开胃酒，这样我就可以不要喝醉了虽然我半想喝醉因为我终于在经历了几次爱情之后又一次找到了爱情，其实是在我一生中的一次伟大的爱抛弃了我之后，就像她抛弃了一个法国电影，用模糊的字幕，没有性爱，甚至没有裸露的屁股蛋，而且我已经不再思念我生命中的爱了而且生活中有多次爱情也好，不过没什么可以写成个歌剧的，而歌剧是唯一的一种有价值的艺术形式，而我一直希望在我的心里有个歌剧，不是要写的而是要生活的。

Dealcoholization temperature markedly influences the surface area and porosity of the resultant MAO-supports. When the support was pretreated at lower or higher temperature, the corresponding MAO-support shows very low surface area;2.XRD and IR analyses indicate that MAO has reacted with the residual ethanol in the supports, which is an important manner to get MAO fixed on the carrier. Morever, XPS analyse indicates that MAO can also be coordinated with MgCl_2, which is another way to get MAO fixed on the support;3.ICP and EDX analyses indicate that dealcoholization temperature not only determined the element content on the solid catalyst, but also influences the element distribution on the carrier;4.The activities of the supported phenoxy-imine catalysts and the properties of resultant polymers are strongly dependent on the dealcoholization temperature. The support (MSP-5) obtained by treating MgCl_2·2.56C_2H_5OH at 160℃for 4 h, then modified by MAO is very effective for immobilizing complex 3, the resultant solid catalyst (MSPC-5) shows very high activity in ethylene polymerization, and its kinetics of polymerization is stable during the reaction process. Finally, PEs with spherical morphology and high bulk density (over 0.35g/ml) were obtained, without reactor fouling;5.In this work, polymerization conditions such as alkylaluminums, Al/Zr ratio, temperature and H_2 had a pronounced effect on the activity of MSPC-5 and properties of PE;(3). New MgCl_2-Supported Single-Site Catalysts for Ethylene PolymerizationIn this work, a kind of new MgCl_2 support was obtained by anhydrous MgCl_2 co-milled with solid MAO, and it is a creative contribution. Then some single-site catalysts were supported on the new MgCl_2 support, and the resulted solid catalysts were tested in ethylene polymerization, the results indicated that:1.XRD and IR analyses indicate that MAO does be coordinated with MgCl_2, which is in good agreement with the results obtained by XPS;2.co-mlling time had no obvious effect on the texture of support after 12 hours;3.In this work, MgCl_2 was co-milled with solid MAO for different hours, and then complex 3 was supported on these co-milled supports. It was found that co-milling time markedly influences the activity of solid catalysts, but it had negligible effect on the kinetic profile and the properties of resultant PE.

XPS研究结果表明，MAO不仅仅只和乙醇作用，MAO还与MgCl_2本身有一定的作用，这是一个极为重要的发现；3、通过ICP和EDX表征，发现载体的脱醇温度直接影响着元素在固体催化剂中的含量及分布；4、脱醇温度极大地影响着负载苯氧基亚胺类催化剂的活性和聚合物的性能，特别是原始载体经160℃活化4小时制备得到的固体催化剂MSPC-5的活性明显高于其他脱醇温度条件下制得的固体催化，并且催化剂寿命长，表现出稳定的动力学行为，最终获得了高堆密度(大于0.35g／ml)的球形聚乙烯颗粒；5、本文选择MSPC-5为研究对象，考察了聚合反应参数对催化剂的活性及其聚合物的影响，研究发现：不同的烷基铝对催化剂具有非常重要的影响，特别足TIBA对MSPC-5的助催化活性最高，烷基铝的加入量有一个较佳值，聚合温度为80度时活性最高，H_2的加入使催化剂的活性明显降低且聚合物的分子量也减小；、新型氯化镁载体负载单活性中心催化剂催化乙烯聚合本文创造性采用固体MAO与无水氯化镁直接进行共研磨，制备出了一种的新型的氯化镁载体，并将该载体用于多种单活性中心催化剂的负载化研究，研究表明：1、通过BET、XRD的表征，再次证实了MAO与MgCl_2之间具有直接作用，与XPS的研究结果相一致；2、当研磨时间高于12小时时，延长研磨时间对载体的结构没有显著的影响；3、将配合物3负载于共研磨时间不同的一系列载体上，乙烯聚合结果表明，尽管共研磨时间对负载催化剂的活性具有明显的影响，但是它对聚合物的性能以及催化剂的影响不明显。

Dealcoholization temperature markedly influences the surface area and porosity of the resultant MAO-supports. When the support was pretreated at lower or higher temperature, the corresponding MAO-support shows very low surface area; 2.XRD and IR analyses indicate that MAO has reacted with the residual ethanol in the supports, which is an important manner to get MAO fixed on the carrier. Morever, XPS analyse indicates that MAO can also be coordinated with MgCl_2, which is another way to get MAO fixed on the support; 3.ICP and EDX analyses indicate that dealcoholization temperature not only determined the element content on the solid catalyst, but also influences the element distribution on the carrier; 4.The activities of the supported phenoxy-imine catalysts and the properties of resultant polymers are strongly dependent on the dealcoholization temperature. The support (MSP-5) obtained by treating MgCl_2·2.56C_2H_5OH at 160℃for 4 h, then modified by MAO is very effective for immobilizing complex 3, the resultant solid catalyst (MSPC-5) shows very high activity in ethylene polymerization, and its kinetics of polymerization is stable during the reaction process. Finally, PEs with spherical morphology and high bulk density (over 0.35g/ml) were obtained, without reactor fouling; 5.In this work, polymerization conditions such as alkylaluminums, Al/Zr ratio, temperature and H_2 had a pronounced effect on the activity of MSPC-5 and properties of PE;(3). New MgCl_2-Supported Single-Site Catalysts for Ethylene Polymerization In this work, a kind of new MgCl_2 support was obtained by anhydrous MgCl_2 co-milled with solid MAO, and it is a creative contribution. Then some single-site catalysts were supported on the new MgCl_2 support, and the resulted solid catalysts were tested in ethylene polymerization, the results indicated that: 1.XRD and IR analyses indicate that MAO does be coordinated with MgCl_2, which is in good agreement with the results obtained by XPS; 2.co-mlling time had no obvious effect on the texture of support after 12 hours; 3.In this work, MgCl_2 was co-milled with solid MAO for different hours, and then complex 3 was supported on these co-milled supports. It was found that co-milling time markedly influences the activity of solid catalysts, but it had negligible effect on the kinetic profile and the properties of resultant PE.

XPS研究结果表明，MAO不仅仅只和乙醇作用，MAO还与MgCl_2本身有一定的作用，这是一个极为重要的发现； 3、通过ICP和EDX表征，发现载体的脱醇温度直接影响着元素在固体催化剂中的含量及分布； 4、脱醇温度极大地影响着负载苯氧基亚胺类催化剂的活性和聚合物的性能，特别是原始载体经160℃活化4小时制备得到的固体催化剂MSPC-5的活性明显高于其他脱醇温度条件下制得的固体催化，并且催化剂寿命长，表现出稳定的动力学行为，最终获得了高堆密度(大于0.35g／ml)的球形聚乙烯颗粒； 5、本文选择MSPC-5为研究对象，考察了聚合反应参数对催化剂的活性及其聚合物的影响，研究发现：不同的烷基铝对催化剂具有非常重要的影响，特别足TIBA对MSPC-5的助催化活性最高，烷基铝的加入量有一个较佳值，聚合温度为80度时活性最高，H_2的加入使催化剂的活性明显降低且聚合物的分子量也减小；、新型氯化镁载体负载单活性中心催化剂催化乙烯聚合本文创造性采用固体MAO与无水氯化镁直接进行共研磨，制备出了一种的新型的氯化镁载体，并将该载体用于多种单活性中心催化剂的负载化研究，研究表明： 1、通过BET、XRD的表征，再次证实了MAO与MgCl_2之间具有直接作用，与XPS的研究结果相一致； 2、当研磨时间高于12小时时，延长研磨时间对载体的结构没有显著的影响； 3、将配合物3负载于共研磨时间不同的一系列载体上，乙烯聚合结果表明，尽管共研磨时间对负载催化剂的活性具有明显的影响，但是它对聚合物的性能以及催化剂的影响不明显。

Base on above studies, some conclusions were obtained as follows:(1) ore-forming background of the studied ferromanganese crusts are mainly controlled by intensity of Antarctic Bottom Waters and variations of material source;(2) it is confirmed that the ferromanganese crusts are mainly hydrogenetic and their composition are affected by volcanic and continental material simultaneously; there are no obvious phosphatization reconstruction and element reaction occurred in them, so they have important paleoceanological significance;(3) from researches on element occurrence modes in the new-type ferromanganese crusts and the lying sediments, it is proposed that there is no great biological affection on the crusts formation and their composition mainly came from the adsorptive action of the ferromanganese oxides in them;(4) two major types of ore-controlling factors are identified through compilation of ore-controlling factors, which are geological and oceanic factors;(5) considering the long-term variation trends of the crusts composition, combing the U-series and 10Be isotope dating results, it is proposed that the ore-forming processes of ferromanganese crusts in the studied areas can be divided into three major stages (5.6~2.8 Ma, 2.8~2.7 Ma and since 2.7 Ma), and then the activities of AABW since the Late Miocene, changes of input flux coming from volcanic and continental material are confirmed.

通过研究，得出如下结论：(1)研究区铁锰结壳的成矿背景主要受控于南极底流强弱及物源供给的变化；(2)证实铁锰结壳主要为水成成因，同时其物质组成也受一定程度的火山和陆源物质的影响；结壳自形成以来没有遭受到明显的磷酸盐化等成岩后期改造和元素再迁移，具有重要的古海洋学意义；(3)通过新型铁锰结壳及下伏沉积物元素赋存状态的研究，认为生物作用对研究区结壳的形成并没有很大的直接影响，其物质成分主要来自于结壳中铁锰氧化物的吸附作用；(4)在控矿要素的研究中，归纳出了地质与海洋两大类结壳控矿要素；(5)根据结壳成分长周期变化趋势，结合铀系和10Be测年结果，将研究区结壳的形成过程划分为三个主要阶段(5.6~2.8 Ma，2.8~2.7 Ma和2.7 Ma以来)，并确定了晚中新世以来研究区南极底流的活动情况、火山和大陆来源物质输入量的变化。

The main research tasks and results are as follows:(1) Through comparing the stress intensity factor of compact tension specimen calculated by finite element software with the theoretical value, the feasibility of calculating fracture parameters of crack tip in ABAQUS software was verified.(2) The relationship between the elastic modulus of the material and research scale was studied based on deriving the cohesive stress theory and other relevant theories. And the elastic modulus of the material on meso-scale was determined.(3) Global model and sub-model of the finite element were built in th...e macro-scale, and stress-strain field nearby the crack tip was analyzed, and the results show that the detailed stress-strain in the crack tip could be obtained by using the sub-model technique.(4) In meso-scale, the crack growth model was also established by assuming the crack propagating along the grain boundary, and the detailed stress-strain field in the crack tip was obtained.(5) The effect of crack length on Von Mises stress, and maximum principal stress and strain was analyzed in meso-scale when equivalent KI equals 30MPa.m1/2. And the results show that except for crack tip area, the stress-strain distribution in whole specimen is not affected.

主要完成研究内容和取得成果如下：(1)利用有限元软件计算出紧凑拉伸试样的裂纹尖端应力强度因子KI值，其结果与理论值一致，从而验证了利用ABAQUS计算裂纹尖端相关断裂参量的可行性；(2)在研究内聚应力等相关理论的基础上，推导出了研究尺度与材料弹性模量的近似关系，并确定了介观尺度上的弹性模量；(3)在宏观尺度上建立了全局有限元计算模型和子模型，得到了裂纹尖端应力应变场分布，结果表明利用子模型技术获得比较准确的裂纹尖端应力应变场分布是可行的；(4)在介观尺度上利用平均晶粒尺度的方式建立了裂纹沿晶扩展模型，得到了裂纹尖端断裂过程区的微观应力应变场；(5)当应力强度因子为30MPa.m1/2时，分析了介观尺度上在裂纹沿晶扩展过程中裂纹长度对Mises应力、最大主应力和应变的影响，结果表明，裂纹扩展长度对试样整体应力应变分布影响不大，而对裂纹尖端区域有较大影响；(6)介。。。

An equal cross-section blade was investigated and a finite element model was built parametrically. Geometrical parameters (such as length, width and thickness), material parameters (such as young's modulus and density) and speed of blade were considered as input random variables while the static frequencies and dynamic frequencies were output random variables. Combining the finite element method, response surface method and Monte Carlo method, the statistical properties and cumulative distribution functions of static frequencies and dynamic frequencies were obtained. Probability sensitivities analysis, which combined the slope of the gradient and the width of the scatter range of the random input variables, was applied to quantitatively evaluate the sensitivities of static frequencies and dynamic frequencies with respect to the random variables. The Scatter plots of structural responses with respect to the random input variables were illustrated how to adjust the values of the static frequencies and dynamic frequencies by changing input random variables.

文中以某试验台用汽轮机等直叶片为研究对象，考虑几何参数、材料参数和转速的随机性，通过有限元参数化建模，将确定性有限元方法、响应面方法和Monte-Carlo模拟法相结合，从而获得了叶片静频、动频的统计特性和累积分布函数；同时考虑随机变量的梯度和离散范围对静、动频的影响，通过概率敏感性分析，定量地判断出叶片静、动频对随机输入变量的敏感性；通过绘制叶片静、动频与输入变量的散点图，定量地分析了如何改变随机变量以调整静、动频率的方法。

This product union and the optimal near ten years for the domestic feed enterprise, the cultivation factory design's cattle and sheep feed formula, strengthened Va, Vd, Ve, the nicotine acid and the biological element specially and so on, and have included the rumen protein, the rich electrolyte, the trace element, the chelating agent, the seasoner, metabolism regulation medicinal preparation, the nutrition comprehensive and are balanced, may adjust the meat cattle and sheep microcycle, maximum limit enhance the meat cattle's and sheep's protein and do the material amount of radiation, display its heredity potential fully, enhance the cattle and sheep to increase the heavy speed.

本产品结合和优选近十年为国内饲料企业、养殖厂设计的牛羊饲料配方，特别强化了 Va 、 Vd 、 Ve 、烟酸和生物素等，并含有过瘤胃蛋白质、丰富电解质、微量元素、螯合剂、调味剂、代谢调控剂，营养全面且平衡，可调节肉牛羊微循环，最大限度的提高肉牛羊的蛋白质及干物质摄入量，充分发挥其遗传潜力，提高牛羊增重速度。

Bob Eckert has been chairman and chief executive of Mattel for eight years.

美泰董事长兼首席执行官鲍勃·埃克尔特在任已8年。

The outlook for honors and disgraces carries on and surpasses the traditional outlook for honors and disgraces theoretically, and carries on and develops the theory of construction of socialist mora...

社会主义荣辱观的提出在理论上是对传统荣辱观的一次继承和超越，是对社会主义道德建设理论的继承和发展，在实践上有利于形成良好的社会风尚。