效应基因

All of gene effects for the final characters were found to be algebraic sum of the respective parameters for net growths at different development stages.

不同发育阶段基因效应的符号、显著性关系及遗传模型的明显差异被认为是不同发育阶段由不同基因作用的结果。

Besides, HIF-1 can quickly induce a lot of expressions and the adjustment of anoxia-induced genes, so as to enhance the hypoxia-induced genetic transcription and increase the expressions, and engender physiological effects, such as adjusting the transcription of EPO genes to increase their production, thereby the red blood cells quantity is enlarged, which strengthens the ability of oxygen transportation and mitigates anoxia; adjusting VEGF genetic transcription to engender more blood capillaries, consequently the transportation and supply of oxygen and substance of energy source are strengthened; adjusting the glycolytic enzyme to enhance glycolysis ability under anoxemia condition and increase energy supply; functioning on HO-1 genes in vascular smooth muscle cells to produce HO-1, which can engender NO and CO as pneumatic signal molecules to activate the guanylate cyclases, thus CGMP level is improved to make the vascular smooth muscles chalasia, to restrain platelet agglutination, so that theblood flow and vascular permeability are increased, and the anoxic tissues obtain ample oxygen supply, etc..

在低氧环境中，HIF-1可以被很快诱导大量表达并介导低氧诱导基因的调控，使低氧诱导基因转录增强，表达产物增多，产生生理效应。

Its mode of inheritance may conform to polygenic inheritance with a major autosome recessive gene.

可能符合具有隐性主基因效应的多基因遗传方式。

Chloromycetin had positive effect on BADH gene expression, and the effect might be due to inhibit repressor generation in mitochondria and activate transcription factor of BADH gene.

应用氯霉素的实验表明氯霉素对BADH基因表达为正效应，提出了可能是抑制了线粒体中的阻遏蛋白的产生使BADH基因表达去阻遏。

In present study, we discussed the effects of cell microfilament on the activity of collagen type I alpha 1 chain gene ( COL1A1) promoter under microgravity simulated by clinostat and/or cytochalasin B as microfilament depolymerizer in the established EGFP-ROS cell line using the method of fluorescence semi-quantitative analysis and the fluorescent stain of microfilament.

本研究以构建的基因工程细胞株为对象，以回转器模拟微重力效应，利用增强型绿色荧光蛋白(enhanced green fluorescence protein，EGFP)荧光半定量和细胞微丝荧光染色分析技术，探讨回转模拟微重力条件下，细胞微丝系统对I型胶原a1链基因(collagen type I alpha chain 1 gene， COL1A1)启动子活性的影响。

The dose-effect is relatively ideal,and the HPRT gene mutation can be taken as a radiation biological dosimeter.

克隆法是一种检测放射性核素内、外照射诱发HPRT基因突变的方法，HPRI，基因突变剂量效应关系理想，有可能作为辐射生物剂量计。

With the adenoviral vector we construct,the synthesis shRNA insert the mammalian cells,inducing the DNA silence effect,to research the role of S7 in the genaration and progression of tumor.

我们通过构建腺病毒基因载体，将构建合成的shRNA转入细胞，诱导对S7的基因沉默效应，从而研究S7对肿瘤细胞发生、发展的作用。

Rat glioma cell C6 was infected by the deficiency recombinant retrovirus (named C6TK). The sensitivity of C6TK cells to GCV or ACV increased 450 or 10 times than that of C6 cells respectively. Rat C6 glioma model was successfully built, and SD rats inoculated intracerebrally C6TK cells had normal gliomas. The average survival periods of the rats were about 15 days. However, after treated with ACV, the growth of C6TK tumors obviously regressed, and the survival periods extended to 57.8±8.1 days, especially in rats injected with mixed PA317TK and C6 cells or in situ PA317TK cells, which the tumors nearly disappeared after ACV administration and the survival periods extended to over 120 or 71.4±36.1 days respectively, P＜0.001.

结果：构建了带有HSV-tk基因的反转录病毒载体GINaTK，应用脂质体转移方法将GINaTK导入反转录病毒包装细胞PA317，成为产病毒细胞PA317TK，用带有HSV-tk基因的复制缺陷型反转录病毒感染C6细胞，命名为C6TK细胞，对GCV和ACV的敏感性分别高于亲本450倍和10倍；成功地建立了大鼠脑胶质瘤模型，并证实转染细胞C6TK的成瘤效应未改变，存活期约为15天；而经ACV治疗后，含有C6TK细胞的肿瘤生长明显被抑制，大鼠生存期延长为57.8±8.07天，尤其是采用PA317TK细胞混和治疗组和原位治疗组，肿瘤基本消失，大鼠生存期显著延长，混和治疗组存活120天以上，原位治疗组存活至71.4±36.1天。t检验，P值均小于0.001。

But significant differences were found in coefficient of variation and broad-sense heritability (H2) of the three characters: CV and H2 of self-pollinated fruiting rate were both greatest, with the variation mainly resulted from inheritance, and high inheritance potential; H2 of fertile flower rate was the least and its variation was less from inheritance; CV of average fruit weight was the least and its inheritance potential is small. Thirdly, the ratios of sweet to bitter kernel of F1 progenies in positive and reverse crosses between Katy and Taianshuixing were 18∶16 and 13∶12, and were both in agreement with a 1∶1 segregation by χ2 test, which demonstrated that the bitter kernel character of Katy was heterozygous.

但3个性状的变异系数和广义遗传力(H2)均差异很大，其中自交坐果率的变异系数(101.5%～139.1%)和广义遗传力(87.1%～91.4%)均较大，表明变异主要来自遗传效应，并且自交坐果率的遗传潜能大；有效花比率的广义遗传力最小(36.8%～49.1%)，表明其遗传效应较小；平均单果重的变异系数最小(24.0%～29.7%)，说明平均单果重的遗传潜能小；（3）凯特与泰安水杏正反交的杂种一代甜仁与苦仁的比例分别为18∶16和13∶12，经χ2检验符合1∶1的分离比例，证明控制凯特杏甜仁与苦仁这对性状的基因位点是杂合的。

It is shown that PTDT is a robust and valid approach for mapping QTL of threshold traits. Moreover, PTDT is powerful for marker with multiple alleles and multiple tightly linked markers, too. From the results of simulation on quantitative traits, following conclusions can be derived.

结果表明：(1)PTDT是一个稳健的QTL定位分析方法，在各种参数组合下，其假阳性概率(1型错误)都在设定的显著性水平附近；(2)PTDT不仅可以检测到效应较大的QTL，而且对效应较小的QTL检验功效依然很高；(3)对各种状态1发生率的阈性状PTDT检验功效也很高；(4)对利用多等位基因标记、多个紧密连锁的标记的QTL定位，PTDT依然是一个高效方法。

Since historical times,England ,where the early inhabitants were Celts, has been conquered three times .

从有历史以来，英国，在此地早期居住的是凯尔特人，已经被征服了三次。

Bluetooth OBEX File Transfer Enables the sending and receiving of files on your phone via Bluetooth.

蓝牙OBEX文件移动允许经过蓝牙传送和接受文件。。。。