效应基因

According to the ratio of genotype variance, the boll number is controlled mainly by dominance effects.

从加性效应、显性效应占基因型方差的比值看，显性效应对铃数影响更大。

There are 2 alleles at a marker locus and they are codominant. We assumed that the sires used were heterozygous at all marker loci with known linkage phases and were mated to females which are randomly sampled from a population being in HardyWeinberg equilibrium.For further understanding of the values of treating QTL effect as random effect and the importance of estimating the variance component of QTL, we estimated the additive QTL effect under several factors combinations assuming that the QTL vanance component to be known.

为了进一步明确将QTL效应作为随机效应处理，并估计其方差组分的重要意义，本文在方差组分真值给定的前提下，采用随机QTL效应模型和单标记及侧翼标记信息，研究了不同试验设计、不同群体结构、不同QTL等位基因类型、不同遗传力和不同QTL方差贡献等因素组合下，TM-BLUP种畜遗传评定的效果。

The results showed that these genetic characters were simultaneously influenced by gene additive effect,nonadditive effect and reciprocal-cross effect.

结果表明，萝卜根质量、根长和根茎同时受基因加性效应、非加性效应及反交效应的共同作用。

Electromagnetic radiation has a potential hazard on human health, application of gene chip which is high throughout technique for analyzing differential gene expression will supply bio-effect of electromagnetic with many gene level evidence.

电磁辐射具有潜在的健康危害，基因表达差异的高通量分析技术－基因芯片技术的应用，将为电磁辐射生物学损伤效应提供大量基因水平的根据依据，本文就基因芯片技术在微波、极低频电磁场等电磁辐射领域中的应用及其研究进展进行了综述。

The transforming growth factor-β superfamily, a large group of highly conserved growth factors including TGF-βs, activins and BMPs, regulate a wide variety of cellular functions such as proliferation, differentiation, apoptosis and migration. Signals from these growth factors are transduced by a group of Smad proteins. To date, there are nine vertebrate Smads, including the receptor-activated Smads , Smadsl-3, 5 and 8, the common mediator Smad4 and Smad4β, and the inhibitory Smads, Smad6 and 7. Signaling is initiated when the ligand induces assembly of a heteromeric complex of type Ⅱ and type Ⅰ TGFβ receptors. Then R-Smads are directly phosphorylated by activated type I TGF-β receptors.

在多种SMADS中，SMAD5令我们产生兴趣，基于三个原因：1、Smad5基因敲除胚胎中发现卵黄囊的异位造血以及CFU-GM祖细胞数目增加，表明SMAD5可能是早期造血发育的负向调控基因。；2、应用反义核酸封闭Smad5可以逆转TGF-β对祖细胞增殖的抑制效应，表明它可能介导TGF-β信号转导，后者的异常，包括某些SMADS的功能异常，和白血病紧密相关；3、Smad5基因定位在人染色体5q21，此区域的缺失和急性髓系白血病和骨髓增生异常综合症相关，因此，Smad5被怀疑为白血病抑制基因。

Monogene Ht1, Ht2, Ht3, and Ht were crossed with inbreds of same resistant level and different resistant level to study the monogenic effects and polygenic effects on spots number, size, spread speed, spore production and incubation period.

通过单基因Ht1、Ht2、Ht3、Ht，与同一水平抗性自交系以及与不同水平抗性自交系组配，研究单基因处于杂合状态时在控制病斑数量、面积、病斑扩展速度、产孢量和潜伏期等方面的单基因、多基因的联合效应。

Thus, quantitative traits obey the mixed major gene plus polygenes inheritance model. The model was first introduced and then developed in human and animal genetic studies.

近年的育种实践、QTL定位和一系列遗传研究结果与经典数量遗传学的多基因假说相佐，认为数量性状是由若干效应大小不同的基因所控制，即认同主基因+多基因混合遗传模式。

In this study we mapped a grain length controlling gene named Lk-4 with SSR and CAPs markers by screening 800 recessive plants in a BC2F2 population derived from a cross of Shuhui527×Xiaoli and backcrossed with Xiaoli as the donor parent.

对F2和BC2F2 群体籽粒大小形状和千粒重的遗传分析表明，回交能将大部分对目的基因效应具有干扰修饰作用的微效基因多态性除去，从而有利于对目的基因型的准确鉴定；在F2和BC2F2群体中只发现两类籽粒长短表现型，即短粒和长粒，并且二者分离比例符合3：1的典型一对等位基因分离比例。

The study on themechanisums has been a hotspot of biology and radiobiology.

值得关注的是，自从国外学者提出电离辐射旁效应概念以来，许多研究者证实旁效应的存在，对&照射细胞核才会引起细胞致命的损伤&&只有受照射细胞才受到损伤&等某些传统观念提出了有力的挑战，辐射诱导的基因不稳定性、细胞质受到照射所致的突变及旁效应等在辐射致癌中同样具有重要作用，并得到放射生物学界的确认。

As PTDT does in threshold traits, PTDT is valid not only for different QTL effect level, but also for maker with multiple alleles and multiple tightly linked markers.(2) Under an appropriate selection ratio s (in this study, s is 0.2, 0.4, 0.6, 0.8, respectively), the power of PTDT can be improved and the genotying individuals can be decreased using selective genotyping design. However, the power of PTDT is related with population size and population structure, an appropriate selection ratio can be defined by simulation based on the existing data.(3) Among the three transforming methods, mixed-family selection is the best, full-sib selection has same power to mixed-family selection in many parameter combinations, and Estimated Breeding Value selection is inferior to them.

数量性状QTL定位的模拟研究结果表明：(1)数量性状经有效转化后，PTDT对数量性状QTL定位保持了阈性状QTL定位的稳健与高效，对不同效应大小的QTL(10％，30％，50％)PTDT都是一个有效的分析方法；(2)在多等位基因标记、多标记方面，PTDT的检验功效与阐性状分析时一样高效；(3)在合适的选择率下(本研究的分别为0.2，0.4，0.6，0.8，1.0)，选择性基因型测定不仅可以减少基因型测定的数量，而且可以提高PTDT的检验功效，但选择性基因型测定的PTDT检验功效很大程度上与群体大小和结构有关，这个可根据具体情况通过模拟找到一个合适的选择率；(4)三种转化方法的转化效力结果表明，家系内混合家系选择的转化效力最高，家系内全同胞选择次之，估计育种值选择的转化效力较差。

Chrysanthemum of 10 thousand birthday is lax to edaphic requirement, with the arenaceous qualitative loam with fecund, good drainage had better.

万寿菊对土壤要求不严，以肥沃。排水良好的砂质壤土为好。

He unstepped the mast and furled the sail and tied it.

他拔下桅杆，把帆卷起，系住。