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Although the method have been widely applied in practical engineering. However along with damage accumulating and increase of aging structures, new signal analysis and interpretation algorithm need to be developed in order to accurately evaluate damage.

虽然该方法已在实际工程损伤检测方面得到了较广泛的应用,但是随着损伤的积累以及老化结构的增加,为了更加准确的对损伤进行定位和定量,需要发展新的信号处理方法提取对损伤敏感的特征因子。

The lesion, the changes of activity of cholinesterase and acid phosphatase of motor neurons in lateral nucleus of spinal cord anterior horn, the function of axoplasm transportation and nerve conduction, the regeneration of axons and myelin sheath, and the recovery of sciatic nerve function were examined at 7, 14, 30 and 90 days intervals after operation, using Nissl and enzyme histochemistry staining, electrophysiological technique, hydrogen-peroxide oxidoreductase retrograde trace method, axon image analysis, and measurement of sciatic function index. The spinal cord anterior horn of injury side was compared to the correspondence region of spinal cord.

分别于术后7、14、30和90d应用酶组织化学方法、电生理方法、HRP (hydrogen-peroxide oxidoreductase)逆行示踪方法、轴突图象分析方法以及坐骨神经功能指数(sciatic nerve function index,SFI)测量等方法检测坐骨神经损伤后对应脊髓神经元的存活率、神经元胞体酶系变化、损伤神经在轴浆运输、电传导以及轴突、髓鞘再生等方面的恢复情况,探索外周神经损伤后OECs及几丁质对神经元的保护作用以及对新生神经功能恢复的作用,为外周神经损伤的治疗提供新的理论基础。

An approximate formula of the deflection of a local damaged plate is given and can be realized to identify the damaged amount and locality. As an example, the damaged quadrangular plate with quadrilateral simple hinged restrain is analyzed and is given an analogous formula of its deflection.

另外,用有限元结构分析软件对含损伤的四边简支板进行计算的基础上,提出了一种带损伤板的位移等效模型,可以将对损伤位置及损伤程度的物性识别问题转变成对载荷大小及作用位置的构造识别问题进行处理,从而降低识别问题的非线性程度,提高识别能力,简化识别计算。

The damage distribution and tensile stress in the damage zone are calculated based on a modified Dugdale model and a damage evolution equation.

基于改进的Dugdale模型和已有的材料损伤率,计算了损伤区内的损伤分布和拉伸应力,讨论了损伤在整体材料破坏过程的作用。

Based on a nonclassical theory of plasticity and the continuum damage mechanics,a damage constitutive equation is obtained for the ferrite phase with the damage evolution law for mixed hardening materials from an ellipsoidal void model under particular coordinates,where the void shape variation is considered.

基于非经典塑性理论和连续介质损伤力学,利用在一个特殊坐标系下基于椭球形孔洞模型得到的可考虑孔洞形状变化混合强化材料的损伤演化率得到了铁素体相的损伤本构方程,通过混合物理论利用铁素体和渗碳体相各自本构关系并考虑其几何特征得到了珠光体团的损伤本构模型。

OVCs were isolated by density ladder centrifugation in the 4th week, and then OVC's morphology was observed under transmission electromicroscrope and immunocytochemistry were performed to detect the expression of ICAM-1. Results Observing OVC's morphology under transmission electromicroscrope showed that OVC was infantile and undifferentiated with big nucleus, clear nucleolus, large nucleoplasm-ratio, small mitochondria, and little endoplast.

结果 透射电镜下观察到OVCs超微结构的改变为核大,核/浆比大,核仁小,胞浆内细胞器少,可见少量内质网和小线粒体,整个细胞呈幼稚、未分化状态;ICAM-1免疫细胞化学检测阳性;损伤肝组织HE染色和ICAM-1免疫组化检测显示,肝损伤初期,Hering管周围OVCs增生并且ICAM-1阳性表达,随着肝损伤的加重,OVCs继续增生,并且,OVCs沿增生的肝纤维向肝小叶迁移,同时,ICAM-1阳性表达也继续增多,并逐渐向肝小叶弥散分布;透射电镜下观察到,肝损伤初期,OVCs在Hering管周围增生,肝纤维随之增生,增生的OVCs与肝纤维黏附生长。

OVCs were isolated by density ladder centrifugation in the 4th week, and then OVC's morphology was observed under transmission electromicroscrope and immunocytochemistry were performed to detect the expression of ICAM-1. Results Observing OVC's morphology under transmission electromicroscrope showed that OVC was infantile and undifferentiated with big nucleus, clear nucleolus, large nucleoplasm-ratio, small mitochondria, and little endoplast. In initial stage of damaged liver, OVCs and the expression of ICAM-1 mostly distributed around Hering duct, and then gradually increased and expanded toward hepatic lobule, shown by staining paraffin sections with HE, immunochemistry and transmission electromicroscrope. Immunocytochemistry indicated that ICAM-1 expression on OVCs was positive.

结果 透射电镜下观察到OVCs超微结构的改变为核大,核/浆比大,核仁小,胞浆内细胞器少,可见少量内质网和小线粒体,整个细胞呈幼稚、未分化状态;ICAM-1免疫细胞化学检测阳性;损伤肝组织HE染色和ICAM-1免疫组化检测显示,肝损伤初期,Hering管周围OVCs增生并且ICAM-1阳性表达,随着肝损伤的加重,OVCs继续增生,并且,OVCs沿增生的肝纤维向肝小叶迁移,同时,ICAM-1阳性表达也继续增多,并逐渐向肝小叶弥散分布;透射电镜下观察到,肝损伤初期,OVCs在Hering管周围增生,肝纤维随之增生,增生的OVCs与肝纤维黏附生长。

Results Observing OVC's morphology under transmission electromicroscrope showed that OVC was infantile and undifferentiated with big nucleus, clear nucleolus, large nucleoplasm-ratio, small mitochondria, and little endoplast. In initial stage of damaged liver, OVCs and the expression of ICAM-1 mostly distributed around Hering duct, and then gradually increased and expanded toward hepatic lobule, shown by staining paraffin sections with HE, immunochemistry and transmission electromicroscrope. Immunocytochemistry indicated that ICAM-1 expression on OVCs was positive.

结果 透射电镜下观察到OVCs超微结构的改变为核大,核/浆比大,核仁小,胞浆内细胞器少,可见少量内质网和小线粒体,整个细胞呈幼稚、未分化状态;ICAM-1免疫细胞化学检测阳性;损伤肝组织HE染色和ICAM-1免疫组化检测显示,肝损伤初期,Hering管周围OVCs增生并且ICAM-1阳性表达,随着肝损伤的加重,OVCs继续增生,并且,OVCs沿增生的肝纤维向肝小叶迁移,同时,ICAM-1阳性表达也继续增多,并逐渐向肝小叶弥散分布;透射电镜下观察到,肝损伤初期,OVCs在Hering管周围增生,肝纤维随之增生,增生的OVCs与肝纤维黏附生长。

The same results were observed in the brain of the unilateral pyramidotomy group above the level of the transection site. Below the level of the transection site, the BDA positive fibers were seen in the right pyramid of medulla oblongata and the left dorsal funiculus of spinal cord, but the BDA positive fibers in the left pyramid of medulla oblongata and the right dorsal funiculus of spinal cord were not seen.

锥体束横断损伤大鼠在损伤部位以上可见双侧对称的BDA阳性纤维束,损伤平面以下在右侧延髓锥体和左侧脊髓后索中见有BDA阳性纤维束,损伤侧锥体和右侧脊髓后索中未见有BDA阳性纤维束。

And then the influence of two of the damage models, the Kachanov and the gradient-dependent constitutive equations, on the well-posed properties of the fundamental equations in continuum damage mechanics is studied according to the characteristic method of the quasi-linear partial differential equations under the case of one dimension elastic damage.

首先从非局部理论出发,推导了应变梯度损伤本构方程;然后利用一阶拟线性偏微分方程组的特征理论,在一维弹性损伤情况下分析了两种不同的本构模型,即Kachanov损伤本构方程与应变梯度损伤本构方程,对连续介质损伤力学基本方程适定性的影响。

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