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形成原纤维

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The adventitia might also play an important role in the formation of cerebral AVM formation. The destruction of collagen in the adventitia might be due to the high level of MMP-9 mRNA.

血管内膜的破坏与大脑AVM形成有关;外膜也参与了脑AVM的形成过程;外膜胶原纤维的破坏与外膜中MMP-9 mRNA高含量呈正相关。

Objective To investigate effect of suppression glial fibrillary acidic protein gene expression on glial cicatrix proliferation in vivo.

摘 要:目的研究抑制胶原纤维酸性蛋白基因表达对在体胶质瘢痕形成的影响。

Results The eyeball distorted, intraocular structure disordered and vision lost severely in 3 eyes. Epithelial plugs were found in superficial layer of stroma and Bowman's layer broke and displaced in three cases. Healing and gap of incision presented 29 days after RK in 1 case. There were incision scar, collagen disarrangement and epithelial island in deep incision more than 2 years following RK in two cases, descent's layer broke in 1 case.

结果3例眼球严重变形,眼内结构紊乱,视力丧失。3例角膜浅层切口有上皮栓形成,前弹力层断裂错位;1例术后29d的切口部分愈合部分缝隙存在;2例术后2a以上的切口瘢痕化,胶原纤维排列紊乱,深层切口有上皮岛;1例后弹力层断裂。

ResultsMacroscopic examination showed no excrescence,thrombus formation,arm fractures and corrosion.The devices were covered with collagen fibrosis and discrete endocardial cells,apparent inflammatory infiltration in the devices and around the devices 1 month after implantation.The implants were nearly endothelialized,while the inflammatory reaction relieved gradually,with myocardial cells ingrowth at the edges of the device 3 months after implantation.The devices were completely covered with endocardium and fibrous tissue.Moreover,endothelial cells could be found on the smooth microscrew adaptor.The inflammatory reaction diminished with a few chronic inflammatory cells existing.Neovascularization and lymphatic vessels ingrowth could be observed 6 months after implantation.

结果所有封堵装置表面均没有发现赘生物、血栓形成、支架发生断裂及被腐蚀;术后1个月,封堵装置表面被胶原纤维和散在内皮细胞所覆盖,大量炎症细胞浸润,封堵装置边缘有小灶性炎症细胞浸润;术后3个月,封堵装置表面几乎被内皮细胞所覆盖,炎症细胞较1个月时明显减少,封堵装置内见纤维化,封堵装置边缘心肌细胞浸入;术后6个月,封堵装置表面完全被心内膜和纤维组织所覆盖,伞尖表面光滑并有内皮细胞上爬,炎症反应明显消散,但仍有少量慢性炎症细胞存在,装置内有新生的血管、淋巴管长入。

Connective tissue from the breast cells, elastic fibers composed of collagen fibers, surrounded by glands, and the formation of a strip of solid support, known as COOPER's suspensory ligament, the ligament running from the skin deep skin membrane.

乳房的结缔组织由结缔细胞、弹性纤维胶原纤维所组成,包围着腺体,并且形成支撑固体的带状物,称为 COOPER 氏悬韧带,这些韧带行走于皮肤的深层肌肤膜。

From the outside to the inside , the body skin is divided into the stratum corneum , stratum lucidum , stratum granulosum , stratum spinosm and stratum basale , after through stratum corneum , stratum lucidum , stratum granulosum , stratum spinosm EGF can reach the stratum basale: accelerate the basal cells prpliferation and differentiation , reverse matured cells' differentiation to make stem cells that will form a " stem cells island " with a certain amount , which accelerate the generation of new cellls , make senescent cells keratinize and shed rapidly , make broken and denatured collagen fibers and elastic fibers repaired , so the skin's elasticity increase , and the wrinkles calm down or disappera gradually .

体表皮由外及里共分为角质层、透明层、颗粒层、棘细胞层、基底层,EGF可以通过透明层、颗粒层、棘细胞层深入肌肤基底层,加速基底层细胞增殖分化,将已经分化成熟的细胞逆分化成干细胞,当达到一定量时,便会形成&干细胞岛&,加速新细胞的生成,让衰老细胞快速角化、脱落,已断裂、变性的胶原纤维和弹性纤维得到修复,皮肤弹性增加,皱纹逐渐平复、消失。

Desmodium pulchellum has the effect on antihepatic fibrosis. The mechanism is possibly concerned that it can make liver cell immune against injure and deduce indirectly the forming of liver collagen protein.

排钱草具有抗肝纤维化作用,其机理可能与其能保护肝细胞免受损伤破坏,从而间接减少肝内胶原纤维形成有关。

There were more fibroblasts, the collagen increased in model control group. After 30 days, the fibroblasts of model control group were hyperemic, scattered red blood cells could be found, and capillaries were proliferated. Fibrous tissue arranged in rows in the acupotomology intervention group and the blockade control group.

造模后30 d模型对照组成纤维细胞增生,可见红细胞散在分布,有增生的毛细血管;针刀干预组与封闭对照组可见纤维组织排列成行;针刀干预组较其他各组胶原纤维形成减少,瘢痕面积小。

The atomic architecture of a spine, from the fibril-forming segment GNNQQNY of the yeast prion protein Sup35, was recently revealed by X-ray microcrystallography.

最近通过X射线微晶学揭示了淀粉样原纤维的原子构造核心:从原纤维形成酵母prion蛋白质Sup35的GNNQQNY片段。

The periostea of both experimental and control side of the mandibular ramus were taken and prepared, 2 of each 5 rabbits in a group were prepared for HE stain detection and 3 for proliferating cell nuclear antigen immunohistochemical detection.Results:1, The newly formed bone was detected on the lateral aspect of mandibular ramus after periosteal distraction. The bone was shaped like a hill. It looked very low and was full of holes at postoperative day 28. With the time of consolidation period lengthened, the newly formed bone matured gradually. X-ray examination showed the new bone shaped like a hill. The average values of new bone height at postoperative days 28,35,42 and 56 were 1.86 + 0.15mm, 2.29 + 0.29mm,3.19 + 0.13mm and 4.70 + 0.45mm. Histological examination of both HE stain and picricacid-fuchsin stain showed the increase in the number of osteoblasts and the change in the orientation of collagen fibers and bone trabecula. There were no significant differences between newly formed bone and original bone on the lateral aspect of mandibular ramus at postoperative day 56 histologically.2 Compared with the control side, the distracted periostea proliferated obviously under the microscope, and the number of periostealcells increased with satiation of cellular nuclear per unit area. The images of PCNA immunohistochemical stain of periosteum showed that the experimental periosteum proliferated obviously after distraction compared with the control side.

结果:骨膜牵张成骨的实验研究南京医科大学硕{学位论文l、骨膜牵张后,可见下领升支外侧的骨皮质上有新骨形成,新骨呈山峰状凸起,术后第28天的新生骨较低平,多孔隙,随着固定时间的延长,新骨逐渐成熟;下领升支前后向切线位X线投照显示新骨呈山峰样隆起;经测量,术后第28、35、42和56天组平均新生骨厚度分别为x.86士0.15mm、2.29士0.29mm、3.19士0.13mm和4.70 土0.45mm;脱钙骨组织的HE染色和不脱钙骨组织的苦味酸一品红染色的组织学观察均显示了新生骨在成骨细胞数量上的增长,以及胶原纤维和骨小梁排列方向上的变化,术后第56天的新生骨在组织学上与原升支骨组织已无明显区别。2、HE染色显示,与对照组相比较,实验侧骨膜增生明显,细胞间排列紧密,单位面积内骨膜细胞数增多,细胞核饱满;骨膜PCNA 免疫组化染色显示,与对照侧相比较,实验侧骨膜在牵张后出现了明显的增生迹象,PCNA阳性细胞分布紧密,单位面积内阳性细胞数较对照组多,靠近骨表面的骨膜中的阳性细胞数更多而且分布更为紧密。

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