局部作用

Observing the effects of DS on acetic acid-induced writhing and increased capillary permeability in mice when it was administered intraperitoneally, the granuloma formation induced by cotton pellet in rat when it was applied locally, and the mucous membrane irritation of DS lozenge.

观察双氯芬酸钠低剂量低浓度腹腔给药对醋酸致小鼠扭体作用及毛细血管通透性增加的影响，局部给药对大鼠棉球肉芽形成的影响，局部长时间接触对的刺激作用。

Objectives: To observe the influence of Danshen to the expressions of mRNA and protein of local hypoxia inducible factor-1α(HIF-1α) during acute ischemia reperfusion injury of skeletal muscles in SD rats, and its effects on the changes in erythrocyte aggregation index, erythrocyte deformation index, local swelling coefficient and histology of the left cremaster muscles of SD rats during ischemia reperfusion injury, therefore to discuss the influence of Danshen to the oxygen environment and hemorheology of skeletal muscle during ischemia reperfushion injury.

目的：通过建立SD大鼠左侧提睾肌的缺血再灌注损伤模型，观察丹参对SD大鼠骨骼肌缺血再灌注损伤局部缺氧诱导因子1α（Hypoxia Inducible Factor-1α，HIF－1α）mRNA及其蛋白表达的影响、对红细胞聚集和变形指数的变化、局部肿胀系数的变化以及组织形态学改变的作用，探讨丹参对缺血再灌注损伤骨骼肌局部氧环境及血液流变性的影响。

Conditions of the seepage and stress is a dynamic process, and also shows its interaction and interdependence. Owing to the closure of the fracture, the hydraulic gradient and the permeability pressure of the fracture turn large, and also promote the expansion of water cracks, and fissures connectivity increasing. The increase of the crack opening width will result in the increase of the infiltration capacity and seepage flow, and the reduction of seepage pressure. Because of the dynamic dependence of the fracture aperture, pressure and seepage, under certain conditions, changes in fracture aperture can lead to the formation of local water-passage, and the local emission of high pressure water, and thus promotes the formation of the sudden outgush disasters.

结果表明：洞室开挖完成后，在围岩渗流与应力耦合作用下，围岩中裂隙隙宽、裂隙中水压及其渗透流量的变化是一个动态过程，且相互作用与相互依赖；裂隙的闭合使得结构面水力梯度变大，作用在裂缝上的渗透压力增大，促进导水裂缝扩展，裂隙连通性增加；裂缝张开度增大，渗透能力增强，渗流量增大，其渗流压力相应降低；由于围岩中裂隙隙宽、压力和渗流量的动态依赖性，在一定条件下，裂隙隙宽的改变可导致局部水力通道的形成，高压水头从局部涌出，从而促进突水灾害的形成。

The recovery of blood circulation of ischemia semidarkness region, improvement of partly hypoxia state and prevention of more serious of impaired are key point in the stroke treatment. This experiment is designed to observe the blood vessel regeneration of ischemia injured region, and observe the variance of partly PCNA and VEGF expression. Combine with limbs functional recovery, we validate the therapeutical effect of acupuncture and investigate the possible mechanism of action.

尽早恢复缺血半暗区的血液循环，改善局部缺氧状态，防止损伤的进一步加重是脑卒中治疗过程中的重点，本实验从缺血损伤区血管再生为切入点，观察局部PCNA、VEGF表达的变化，结合肢体功能恢复情况，验证针刺的治疗作用，并探讨可能的作用机制。

The four-week twice immunized hamsters acquired anti-MP in-fection capacity in local respiratory tract,as a result that swab culuturepositise was belove that of unimmunization group,and that only onehumster's lavage fluid culture was positive in immunization group.How-ever,unimmunization group positive rate of swabs and lavage fluid cul-ture was very high.This hinted that local respiratory tract's anti-MPinfection capacity was weak at the primary infection and the ability de-veloped gradually.4.The sIgA change in broncheal-lung lavage fluid.

而未免疫组咽拭子和支气管肺泡灌洗液MP分离培养的阳性均很高，说明在初次感染时，呼吸道局部防御清除MP的作用差，但随着时间的推移，其灌洗液培养的周次阳性率有下降趋势，MP培养的滴度亦随之降低，说明在感染以后随着时间的推移，呼吸道局部逐渐产生了防御、清除MP感染的作用。

In the presence of L-isoproterenol (through local infusion into area CA1), the theta-pulse stimulation with the parameter of 10 Hz, 150 pulses/train, 1 train, a frequency weakly modifying synaptic strength, induced a robust LTP, and this effect was blocked when DL-propranolol was co-administered. By contrast, the theta-pulse stimulation with the parameter of 5 Hz, 150 pulses/train, 3 train, a frequency strongly modifying synaptic strength, induced a significantly smaller LTP when DL-propranolol was administered into area CA1. Accordingly, DL-propranolol impaired rat's spatial learning in the water maze when infused into area CA1 20min pretraining.

正常情况下对突触传递效能仅有微小调制作用的10Hz的θ节律刺激（每串150个脉冲，1串），在CA1区局部给予L-异丙肾上腺素后，显著地诱导出LTP，这一效应可被DL-心得安所阻断；相反，正常情况下对突触传递强度有显著调制作用的5Hz的θ节律刺激（每串150个脉冲，3串），在CA1区局部给予DL-心得安后，所诱导出的LTP被显著压抑。

The present study has demonstrated the pattern of TNF-α and IL-6 expression, has defined the effect of cellular immunity on BMP-induced osteogenesis at the implant site, and has clarified the immunoregulation by BMP subsequent to bone xenografting, thus opening up a new field of molecular immunology associated with bone xenograft, allowing for the search for a more ideal approach to preventing immune rejection and developing a highly effective xenogenous graft material.

本研究结果揭示了异种骨移植局部TNF-α和IL-6的定位表达及其规律，基本上阐明了移植局部细胞免疫对BMP诱导成骨作用的影响及BMP在异种骨移植局部的免疫调节作用等问题，开辟了异种骨移植分子免疫学新领域，并为选择更理想的移植排斥防治途径和研制高效的异种骨移植材料提供了可靠的实验及理论依据。

The main role for the Line Up Competition Algorithm LCA is in global research , while Speediest Descent Algorithm SDA is in local search .

其中，列队竞争算法的主要作用是实现全局搜索，而梯度法的作用是实现局部寻优，这两种方法的结合，可以使全局搜索与局部搜索达到均衡和统一。

The main role for the Line-Up Competition Algorithm LCA is in global research, while Speediest Descent Algorithm is in local search. The computations show that the hybrid algorithm is superior to single one.

其中，列队竞争算法的主要作用是实现全局搜索，而梯度法的作用是实现局部寻优，这两种方法的结合，可以使全局搜索与局部搜索达到均衡和统一。

According to the characteristics of cervical disease and cervical human natural physiological curvature, Head back to use the self continue to play a small role in the weight of traction, the 26 Pillow taste of Chinese herbal medicine, directly on the neck and improve local blood circulation, ease muscle cramps, relieve the sense of Feel oppressed nerve endings to reduce the local tissue tension, anti-inflammatory, analgesic, sedative, to ease rapidly brought about by a variety of cervical spondylosis discomfort, treatment and prevention is ideal for cervical spondylosis.

根据颈椎病的发病特点及人体颈椎自然生理曲度，利用头部后仰的自重起到持续小重量的牵引作用，枕芯的26味中草药，直接作用于颈部，改善局部血液循环，缓解肌肉痉挛，减轻感觉神经末梢压迫，减少局部组织张力，消炎、镇痛、安神，迅速缓解颈椎病带来的各种不适，是治疗和预防颈椎病的理想产品。

Chrysanthemum of 10 thousand birthday is lax to edaphic requirement, with the arenaceous qualitative loam with fecund, good drainage had better.

万寿菊对土壤要求不严，以肥沃。排水良好的砂质壤土为好。

He unstepped the mast and furled the sail and tied it.

他拔下桅杆，把帆卷起，系住。