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Actinomycin D is the potent inhibitor of RNA synthesis, and is demonstrated to be able to induce Sf-9 cell, K562 cell, aleolar macroages cell CTLL-2 and Jurkat cell apoptosis.

放线菌素D是RNA合成抑制剂,具较强的诱导细胞凋亡的能力,实验证明放线菌素D可诱导Sf-9细胞,人白血病细胞株K562,肺泡巨噬细胞,CTLL-2和Jurkat细胞等凋亡。

Objective To investigate the resistance of erthromycin and clidamycin in Gram-positive coccus and help to reasonably use clindamycin. Methods Use of MIC to detect 578 isolates randomly collected from January to September in our hospital, double antimicrobial agents detect the clidamycin induce test.

目的 探讨阳性球菌中红霉素诱导克林霉素耐药性的发生情况,合理指导临床用药方法 MIC法检测某院579株阳性球菌对克林霉素和红霉素的耐药情况;双纸片法检测可诱导克林霉素耐药。

In 5 μM. pseudolaric acid B-treated HeLa cells, caspase-3 proenzyme decreased followed by the degradation of caspase-3 substrates, ICAD (inhibitor of caspase dependent DNase) and PARP poly-(ADP-ribose polymerase.

土槿皮乙酸5μM作用于HeLa细胞后,caspase-3的酶原被降解,caspase-3底物ICAD(inhibitor of caspase activated DNase)和PARPpoly-(ADP-ribosepolymerase降解,caspase-3的抑制剂可部分抑制土槿皮乙酸诱导的细胞死亡,表明土槿皮乙酸诱导HeLa细胞凋亡时激活了caspase-3。

In theory, on entry into endosome of tumor cells immunoGrB protein releases C-terminal PE Ⅱ-GrBa into cytosol as a result of auto-cleavage of peptide bond between Arg279 and Gly280. Two kinds of PE translocating peptides covering 253-364 aa and 253-358 aa were compared for their endosome-disruptive function.

一方面,从瞬时表达、可诱导表达和组成性表达三方面研究证明,N端部分PE Ⅱ序列(PE 280-364 aa和280-358 aa)的存在基本不影响GrBa诱导转染细胞死亡的作用。

The resultsshowed that one electron was photochemically transfered from rich electron part inside the C〓 derivatives to C〓 football. On the other hand,two step PET took place between C〓 and additional electron donor Et〓N, and so C〓anion as well as C〓 dianion could be detected in C〓/ Et〓N system.

结果表明:C〓衍生物分子内的富电子部分与C〓区域间发生分子内光诱导的一步单电子转移过程,对比而言,C〓分子与外加给体Et〓N间可相继发生两步光诱导电子转移反应,依次生成C〓和C〓阴离子自由基。

The results showed that both sporophores and stromata of Cordyceps militaris had high content of polysaccharide. And polysaccharide content in stromata was 2-4 times higher than that in sporophores. CMPS could decrease the AST, ALT and MDA levels, and restore GSH-Px content and cell viability remarkably in supernatant of cultured hepatocytes injured by CCl4 induction.

结果表明:蛹虫草的子实体和基质都含有丰富的多糖,其中基质中的多糖含量最高,约为子实体的2~4倍;CMPS可明显降低由CCl4诱导的损伤肝细胞培养上清液中谷草转氨酶、谷丙转氨酶的活性水平和丙二醛的含量水平,显著提高由CCl4诱导的损伤肝细胞培养上清液中谷胱甘肽过氧化物酶活性和诱导损伤肝细胞的存活率。

Result: Shengdi injection could depress the increasing of the amount of total white blood cells and neutrophils and inhibit the increasing of TNF-α, O-2, MPO caused by LPS, as well as relieve the pathologic change including Neutrophils infiltrating and mucous edema in tracheae after intravenous administration. While it did not show the effect on monocyte, and histological lesion of the lung tissue.

结果:生地注射液静脉给药可明显抑制LPS诱导的白细胞总数和中性粒细胞数目升高,对淋巴单核细胞数目无明显影响;明显抑制TNF-α,O-2,MPO水平升高;明显抑制LPS诱导的肺组织中性粒细胞浸润、气管黏膜水肿,对肺组织损伤无影响。

Results:(1) The rats produced amphetamine CPP after treated with 2 mgkg^(-1) amphetamine for 4 days. Ketamine and low, middle, high dose rhynchophylline all could eliminate the CPP effect, and the effect of rhychophylline was increased in a dose-dependent manner. Rhychophylline itself could not induce CPP in normal rats.(2) When compared with normal rats, the NR2B expression in nucleus accubens and amygdaloid of the model rats was obviously increased. Ketamine and middle, high dose rhynchophylline could decrease NR2B expression induced by amphetamine, while low dose rhynchophylline did not affect NR2B expression. Rhynchophylline had no effect on RN2B expression in normal rats.

结果:(1)建立了苯丙胺(2mgkg^(-1),连续4d)诱导的位置偏爱模型,氯胺酮及钩藤碱低、中、高剂量均可消除苯丙胺诱导的位置偏爱效应,随钩藤碱剂量增加其效应加强,且本身无精神依赖性;(2)苯丙胺模型组大鼠伏核和杏仁核NR2B蛋白表达增加,氯胺酮及钩藤碱中、高剂量抑制NR2B表达,低剂量及本身对NR2B表达无影响。

Subthreshold TTT may induce Hsp70 expression in the retina, choroids and laser induced CNV in rats.

阈下能量TTT可诱导大鼠视网膜、脉络膜和激光诱导的CNV表达Hsp70。

Some inductors are poisonous and cannot be used in human.

背景:体外培养扩增的骨髓间充质干细胞可诱导分化为神经细胞,但是有些诱导剂有一定的毒性,不能应用于人体内。

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Cynanchum Lingtai apricot production in the average weight 65 grams, the brightly-colored fruit, juicy rich, sweet-sour taste, sweet from the nucleolus, when the late Qing Dynasty famous Shaanxi, Gansu provinces, the Qing imperial court Tongzhi tribute for years.

灵台生产的牛心杏平均单果重65克,果实色泽鲜艳,汁多味浓,甜酸适口,离核仁甜,清末时就驰名陕、甘两省,清同治年间曾为朝廷贡品。

Chenopodium album,Solanum nigrum, and Amaranthus retroflexus were very susceptible to the herbicides. Polygonum persicaria and Abutilon theophrasti were relatively less susceptible to the herbicides, and Lycopersicon esculentum was not susceptible to it. The relationship between reduction rates of weed biomass and PPM values of weed leaves 2,4, and 6 days after treatment was established.

供试的6种杂草对该混剂的敏感性存在显著差异:红心藜Chenopodium album、龙葵Solanum nigrum和反枝苋Amaranthus retroflexus对该混剂最敏感,ED90值分别为47.65、71.67和29.17g/hm2;春蓼Polygonum persicaria和苘麻Abutilon theophrasti敏感,ED90值分别为96.91、114.20g/hm2;而番茄不敏感。

However, I have an idea.

不过,我有个主意。