查询词典 virulence

Some biological properties of the virus including Virulence, infectivity and antigenicity have great influence on the pathogenesis of the disease.

根据目前的研究，HV病毒的自身因素对HFRS的发病具有非常重要的影响。

There is a complex regulative pathogenic factors excretion mechanism in the pathogens. The appendant genes of agr system is virulence responding regulative factors studied at best in Staphylococcus aureus.

在病原菌中存在复杂的调节致病因子分泌的机制，附属基因agr系统是金黄色葡萄球菌中研究最多的毒力响应调节因子。

Methods The clpE-deficient strain was constructed by LFH-PCR and identified by PCR and sequencing. The impact of clpE mutant on the virulence of S. pneumoniae was evaluated in a mouse model. In addition, we also studied the effect of clpE mutant on adherence and invasion of host cells. Real time RT-PCR was used to measure the mRNA expression levels of autolysin A, pneumococcal surface adhesion A, pneumolysin, pneumococcal surface protein A and neuraminidase The clpE gene was replaced completely by erm cassette.

用长臂同源多聚酶链式反应方法失活clpE基因，用PCR、测序鉴定缺失菌株，通过动物实验观察clpE基因缺失株毒力改变情况，同时用细胞实验比较clpE基因缺失株和野生菌对宿主细胞的粘附和侵袭能力，最后用实时荧光定量PCR分析自溶素(major autolysin A，lytA)、表面黏附素A(pneumococcal surface adhesion A，psaA)、溶血素(pneumolysin，ply)、肺炎球菌表面蛋白A（pneumococcal surface protein A， pspA和神经氨酸酶（neuraminidase， nanA）的表达。

The relationship between protease production and virulence to Bombyx mori was compared.

结果表明，菌株的Pr1产生水平达到最高的时间较总胞外蛋白酶早1～2天。

Systematic infection of mice is used as a model to test the virulence of several mutants. According with their ability to form hyphae, nonfilamentous mutant is avirulent, and hyphae defective mutants have decreased virulence.

用系统感染小鼠模型分析这些突变株的致病能力，同它们形成菌丝的能力相一致，野生菌的致病能力最强，形成菌丝弱的突变株致病能力也减弱，不能形成菌丝的cph1 efg1突变株和crk1则无毒性。

When Shigella flexneri 2a 2457T is cultured at 30℃, it's phenotypically avirulent; when grown at 37℃, its virulence improves greately. There is clear evidence that the temperature-dependent expression of the virulence genes is controlled by H-NS protein.

痢疾杆菌在30℃时不具有侵袭力，37℃时毒力明显增强，已有的研究表明这种依赖于温度的毒力基因的表达受H-NS蛋白的调控。H-NS是一种重要的类核相关蛋白，在革兰氏阴性菌中普遍存在，能够调控大量基因的表达。

The causative agent of the disease is an Corona virus, infectious bronchitis virus IBV）, classified as Corona .Present vaccines for IB are all modified live viruses derived either by sequential passage embrocated chicken eggs. As Immunogenicity of IBV is usually correlated with its virulence, almost all modified live IB vaccines remained insufficient attenuation and have shown a variety of side effects including spread of vaccine virus to no vaccinates, occurrence of long term "carrier" birds, and increasing virulence during in vivo passage.

目前国内外预防本病所用的疫苗大多数是弱毒疫苗，但现用弱毒疫苗都存在以下缺点：（1）与IBV强毒一样，其弱毒疫苗株也能引起潜伏感染，潜伏感染的鸡将终生带毒；（2）疫苗病毒可以由接种鸡传染给非接种鸡，在鸡群之间传播过程中毒力会返强，从而成为新的感染源；（3）传染性支气管炎病毒极易发生变异，且易成为病毒重组的供体和受体，给使用IB传统疫苗预防和根除IB带来极大的困难。

Research topics in the Department are wide-ranging and include the cellular and molecular analysis of infection and immunity, the virulence of enteropathic bacteria, the microbial diversity of tissues, environmental microbiology, innate immunity, human respiratory virology, pulmonary immunology, the virulence of pneumococci, tumour immunology and immunodeficiency.

部门研究主题广泛包括；传染和免疫细胞和分子分析，肠病细菌的毒性，组织微生物的多样性，环境微生物学，先天免疫，人类呼吸器官的滤过性微生物学，肺部免疫学，肺炎双球菌的毒性，肿瘤免疫学和免疫缺陷。

The main virulence factors are CPS, LPS, OMP, TBP, adhesion factors, Apx, Urease and so on. A. pleuropneumoniae produces proteinaceous cytotoxins that is the main virulence factors, ApxⅠ, ApxⅡ, ApxⅢand ApxⅣ. ApxⅡis expressed by all serotypes of A.

Apx毒素是APP最主要的毒力因子，现证明不同血清型的菌株可产生4种Apx，ApxⅡ除血清型10和14以外，其它血清型都分泌；任何血清型都能在体内分泌毒素蛋白ApxⅣ，但体外培养的细菌却不能分泌该毒素。

Culture medium, water volume, root exudates of different crops, temperature, illumination affecting germination conditions of oospores of Phytophthora sojae studied in this reasch and compared the difference of germination of oospores of different race of Phytophthora sojae, filtrated the higher germination rate of strain and suitbable conditions combination of germination of oospores; The pure-line(Race 1) in virulence was obtained through isolation and culture and virulence identify of the second generation. The pure-line was analyzed by molecule method of ISSR. The results were summarized as follows:There was quite difference of germination rate of oospores on different culture medium.

本文测定了不同培养基、水量、农作物根渗出液、温度、光照对大豆疫霉菌卵孢子萌发影响，比较了大豆疫霉菌株间卵孢子萌发的差异，筛选出萌发率较高的菌株和适于卵孢子萌发的条什组合；通过继代单卵孢株分离培养和毒性鉴定，建立了大豆疫霉菌单卵孢株毒性纯系，并分析了单卵孢株毒性纯系后代群体ISSR分子指纹，结果如下： 1。

I'm strongly against the death penalty — it's an eye for an eye.

我不赞成死刑——这是以牙还牙的报复行为。

And to get you the support you need, we're enlisting all elements of our national power: our diplomacy and development, our economic might and our moral suasion, so that you and the rest of our military do not bear the burden of our security alone.

并给你们所须的支援，我们正徵召国家所有各种的力量：我们的外交及发展，我们的经济力量与道德劝说，所以你们与其他军人不须要孤独地负起国家安全的责任。