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Results The positive percentage in superficial gastritis, deep gastritis, gastritic ulcer, duodenal ulcer, chronic atrophic gastritis and gastric cancer, were 70.3, 72.2, 77.7, 69.2 and 25 respectively by URT, 59.2, 77.8, 71.4, 70.7, 75 and 78 respectively by PCR, and 48.1, 61.1, 70.3, 70.7, 66.7, 66.6 and 72.2 respectively by cagA gene probe detection.

但Hp 偏方感染人群大多无症状,只有少数人会表现不同程度的症状,Hp存在不同毒力的菌株〔4,5〕是主要原因爱情之一。cagA+株被大多数学者认为是强毒株,与消化性糖尿病溃疡、萎缩性胃炎、胃癌密切相关〔2,4〕。

Results The positive percentage in superficial gastritis, deep gastritis, gastritic ulcer, duodenal ulcer, chronic atrophic gastritis and gastric cancer, were 70.3, 72.2, 77.7, 69.2 and 25 respectively by URT, 59.2, 77.8, 71.4, 70.7, 75 and 78 respectively by PCR, and 48.1, 61.1, 70.3, 70.7, 66.7, 66.6 and 72.2 respectively by cagA gene probe detection.

但Hp感染人群大多无症状,只有少数人会表现不同程度的症状,Hp存在不同毒力的菌株〔4,5〕是主要原因之一。cagA+株被大多数学者认为是强毒株,与消化性溃疡、萎缩性胃炎、胃癌密切相关〔2,4〕。

The detection rates of methicillin-resistant S. aureus and penicillin-nonsusceptible S. pneumoniae were 15.9% and 84.3%, respectively. The prevalence of ESBLs-producing strains in Klebsiella pneumoniae, Escherichia coli, Serratia spp and Enterobacter cloacae were 31.2%, 46.2%, 94.8% and 16.8% respectively. The resistance rates of Hemophilus influenzae and Hemophilus parainfluenzae to ampicilin were 40% and 36% respectively.

耐甲氧西林金黄色葡萄球菌检出率为15.9%;对青霉素不敏感的肺炎链球菌(包括PISP和PRSP)检出率为84.3%;肺炎克雷伯菌、大肠埃希菌、粘质沙雷菌和阴沟肠杆菌产ESBLs的检出率分别为31.2%、46.2%、94.8%和16.8%;流感嗜血杆菌和副流感嗜血杆菌对氨苄西林的耐药率为36%和40%;铜绿假单胞菌和鲍曼复合不动杆菌对亚胺培南的耐药率分别为10.7%和13.2%。

At the IV dose of 20 and 30 mg/kg, Aloin and Isobarbaloin result appear the mean terminal eliminate half-life(T1/2 β)were 54.1±28.4; 28.7±18.3 and 36.9±21.9;49.7±17.1 min, respectively. The mean area under the serum concentration curve(AUC0-∞)were about 411.655± 13.027;318.213±19.924 and 701.336±116.631;573.278± 86.870μg min/mL, respectively. The mean drug clearancewere 0.165±0.011;0.214±0.016 and 0.149±0.030;0.182±0.035 L/min, respectively.

若静脉注射剂量20和30 mg/kg后,其芦荟大黄苷及异芦荟大黄苷分别平均末端排除半衰期(T1/2 β)为54.1±28.4;28.7±18.3和36.9±21.9;49.7±17.1 min,平均稳定状态分布体积为7.668±3.155;6.343±3.522和5.146±2.490;8.525±2.683 L,平均曲线下面积(AUC0-∞)为411.655 ±13.027;318.213±19.924 和701.336±116.631;573.278±86.870 μgmin/mL,平均血浆中药物最高浓度为23.920±5.669;30.442 ±7.537和57.920±27.690;36.373±14.174 μg/mL,平均药物之清除率为0.165±0.011;0.214±0.016和0.149±0.030;0.182±0.035 L/min。

At the IV dose of 20 and 30 mg/kg, Aloin and Isobarbaloin result appear the mean terminal eliminate half-life(T1/2 β)were 54.1±28.4; 28.7±18.3 and 36.9±21.9;49.7±17.1 min, respectively. The mean area under the serum concentration curve(AUC0-∞)were about 411.655± 13.027;318.213±19.924 and 701.336±116.631;573.278± 86.870μgE min/mL, respectively. The mean drug clearancewere 0.165±0.011;0.214±0.016 and 0.149±0.030;0.182±0.035 L/min, respectively.

若静脉注射剂量20和30 mg/kg后,其芦荟大黄苷及异芦荟大黄苷分别平均末端排除半衰期(T1/2 β)为54.1±28.4;28.7±18.3和36.9±21.9;49.7±17.1 min,平均稳定状态分布体积为7.668±3.155;6.343±3.522和5.146±2.490;8.525±2.683 L,平均曲线下面积(AUC0-∞)为411.655 ±13.027;318.213±19.924 和701.336±116.631;573.278±86.870 μgEmin/mL,平均血浆中药物最高浓度为23.920±5.669;30.442 ±7.537和57.920±27.690;36.373±14.174 μg/mL,平均药物之清除率为0.165±0.011;0.214±0.016和0.149±0.030;0.182±0.035 L/min。

The linear ranges of the calibration curves for lycorine, lycoramine and galanthamine were 5.0-400 mg/L, respectively. Their detection limits were 5.0, 5.1 and 10.2 ng, respectively and the RSD were 2.2%, 5.7% and 4.4%, respectively.

采用三乙胺水溶液(pH9.0)-乙腈-甲醇作为流动相对石蒜碱、力可拉敏和加兰他敏进行HPLC测定,方法的线性范围为5.0~400mg/L,检出限分别为5.0、5.1、10.2ng, RSD分别为2.2%、5.7%和4.4%。

Of planted seedlings and conserved seedlings/saplings, 51.6% and 60.7% survived respectively. Thirteen months later, the seedling heights of Ficus septica, Mallotus repandus, Maacaranga tanarius, Melanolepis multiglandulosa, and Broussonetia kaempferi, and those of Hibiscus tiliaceus, Acacia confuse, and Mellettia pinnata increased more than 130 cm and 50 cm, respectively. The densities of the planted seedlings and conserved seedlings/saplings were 1610 and 680 per hectare, respectively. On the other hand, the density of Leucaena seedlings significantly decreased; and the height of Leucaena stayed steadily during the 13 months.

试验分经银合欢药剂注射处后,采用原生树苗下栽植及保天然新苗木方式进相旧,期间经过2次植栽周边除草抚育作业,栽植苗木及天然新苗木在13个月后之存活分别为51.6及60.7%,密分别为1610株/ha及680株/ha,其中果榕、扛香藤、血桐、虫屎、构树之苗高平均生长在130 cm以上,黄槿、相思树、水黄皮之苗高平均生长在50 cm以上;相对的,银合欢新幼苗在分经药剂处前之平均高为12.3 cm,密为236,000株/ha,药剂处后13个月,幼苗平均高为15.0 cm,幼苗密低至43,000/ha。

Among the cases, hypergranular promyelocytic was present in 15%. Infected bone marrow and megaloblastic anemia were observed in 5% respectively. Fungi infected bone marrow and idiopathic thrombocytopenic purpura were found in 2.5% respectively. Pure red cell aplasia and granulocytic series deficiency due to regenerative granulocyte failure were observed in 2.5% respectively.

在40例艾滋病患者中,反应性早幼粒细胞增多者占15%,感染性骨髓象和巨幼细胞性贫血各占5%,真菌感染性骨髓象和特发性血小板减少性紫癜各占2.5%,纯红再障和生成减少性粒细胞缺乏症各占2.5%。

Results In vitro recovery of the probe was mainly influenced by the perfusion rate. When the perfusion rate was set at 1.0μL/min, in vitro and in vivo recoveries of the probe were 50.16±2.34% and 14.096±0.58%, respectively. The enhancement indexes for 3%, 5% mentha oil were 3.8 and 17.6, respectively. The enhancement indexes were 9.2 and 24.8, for 3% and 5% of Azone, respectively. Conclusion The steady sate flux of meloxicam in rats is significantly improved by enhancer mentha oil and azone.

结果: 在实验条件下微渗析探针的体外回收率主要受灌注液流速的影响,为(50.16±2.34)%;反向渗析法测得探针的在体回收率为(14.096±0.58)%;MO的体积分数为3%和5%时,增渗倍数分别为3.8,17.6;azone的体积分数为3%和5%,增渗倍数分别为9.2,24.8;结论:不同体积分数的MO和azone均可显著增加美洛昔康经皮渗透稳态流量,azone的体积分数为5%时,大鼠角质层的屏障作用可能受到了较大程度的破坏。

The elimination half-life t(subscript β1/2 was 161.10h, 333.21 h and 611.26h, respectively, and the total body clearance was 27.4mL/, 16.8g/ and 18.0g/, respectively. The metabolite ciprofloxacin concentration-time profiles of the plasma, muscle and liver presented similar trend. The multi- peak phenomenon were observed in the plasma, muscle and liver, but the first peak time was 24h, 24h and 12h, respectively. The peak residue of metabolite ciprofloxacin was in liver, muscle and plasma, ordinally. The eliminating rate of ciprofloxacin from muscle and liver was very low.

代谢物环丙沙星在鳗鲡血浆、肌肉和肝脏中药物水平的变化趋势与恩诺沙星基本相似,呈现出多峰现象,但3种组织中环丙沙星出现第一个药峰时间分别为给药后第24小时、24小时和12小时,3种组织中环丙沙星峰值水平肝脏中最高、肌肉中次之、血浆中最低,环丙沙星在肌肉和肝脏中的消除速率比较缓慢。

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