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objectiveto study the protective and therapeutic effects of the extract of retinervus luffae fructus and carapax trionyei on con a-induced hepatic fibrosis in balb/c rats.methodsthe hepatic fibrosis in rats was first induced by intravenous injection of concanavalin a, the treatment in both protective and therapeutic stage was performed by subcutaneous injection of the extract.

目的 探讨鳖甲复方中药针剂对con a在balb/c雄性小鼠中诱导肝纤维化的预防和治疗作用。方法采用con a诱导肝纤维化，造模期间及造模成功后均用复方中药针剂干预药剂组，比较组间各项血液生化指标和肝脏组织学方面的差异，以探讨针剂对肝纤维化的预防和治疗作用。

Objective:To observe the inhibitory effect of EGCG on cataractous lenses of rabbits Dexamethason peroxide induced.To explore the validity of EGCG on the treatment of Dexamethason induced cataract formation.

目的：观察表没食子儿茶素没食子酸酯对抑制地塞米松诱导体外培养兔晶状体上皮细胞凋亡的作用，从而探讨EGCG对晶状体糖皮质激素损伤进行药物治疗的可行性。

However, dexamethasooe did not seem to affect the sustained current and the sustained component of the biphasic current induced by ATP. The in hibitory effect of dexamethasonc on ATP induced currents was blocked by glucocorticoid receptor antagonist RU38486 (10μmol/L) and protein kinase A inhibitor H-89 (10μmol/L), but not by G protein inhibitor GDP-β-S (0.2mmol/L) and protein kinase C inhibitor chelerythrine chloride (10μmol/L).

地塞米松对ATP激活电流的快速抑制作用可被糖皮质激素受体拮抗剂RU38486(10μmol/L)、蛋白激酶A抑制剂H-89(10μmol/L)阻断，而G蛋白激活抑制剂GDP-β-S(0.2mmol/L)、蛋白激酶C抑制剂Chelerythrine chloride(10μmol/L)对地塞米松的快速抑制作用无明显影响。

Results:Oxidized and native LDL-ICboth induced cholesteryl ester accumulation in human macrophages, the level of cellular CE induced by IC were significan...

001，而且随剂量的增加而升高，并转化为泡沫细胞；而天然LDL、抗apoB处理的巨噬细胞内未见胆固醇酯的堆积。

Methods Dietary-induced hyperlipidemia were induced in female SD rats by given 4% cholesterol and 1% cholic acid diet for 16 weeks.

用含4%胆固醇和1%胆酸钠的高脂饲料饲喂大鼠建立高脂模型，观察大鼠血脂、24h尿蛋白、血肌酥和肾小管间质病理改变，免疫组化法检测肾小管上皮细胞巢蛋白和α-平滑肌肌动蛋白表达。

Propofol pretreatment can significantly inhibit ketamine-induced HSP 70 mRNA and protein expression in the posterior cingulated cortex. It may be one of the mechanisms of inhibition of ketamine-induced psychotomimetic effect and neuronal damage by propofol.

结论异丙酚可抑制氯胺酮诱导的HSP 70 mRNA与HSP 70蛋白在大鼠后扣带回皮质区的表达，这可能是其预防或减轻氯胺酮所致精神症状和神经损害的机制之一。

Results The levels of HSP 70 mRNA and HSP 70 protein expression were significantly different among the 5 groups. Ketamine induced marked HSP 70 mRNA and HSP 70 protein expression in the posterior cingulated cortex. Propofol itself did not induce HSP 70 gene expression in this brain region. Propofol significantly inhibited ketamine-induced HSP 70 mRNA and HSP 70 protein expression in the posterior cingulate cortex in a dose-dependent manner.

结果氯胺酮可明显诱导HSP70 mRNA与HSP70蛋白在大鼠后扣带回皮质区的表达；异丙酚自身不能诱导HSP70基因的表达；预先给予异丙酚可显著抑制氯胺酮诱导的HSP70 mRNA和HSP70蛋白在这一区域的表达，且抑制效应呈剂量依赖性。

Methods The compound preparation was administered intragastrically in mice, whose spontaneous activity was observed along with their tolerance of the preparation after long-term administration. The hypnotic effect of the compound was assessed by investigating the changes in the pentobarbital sodium-induced sleeping. The compound was tested for its antiseizure effect in mice with pentetrazole-induced clonic and tonic convulsion. Diazepam was used as the standard control in all experiments.

利用光电计数法观察灌胃给予复方酸枣仁油栀子油对小鼠自发活动的影响，以及长期使用药物对小鼠耐受性的影响；利用延长戊巴比妥钠睡眠时间实验和戊巴比妥钠阈下催眠剂量实验，观察复方酸枣仁油栀子油的催眠作用；利用戊四氮诱发小鼠阵挛性、强直性惊厥观察复方酸枣仁油栀子油的抗惊厥作用；本实验用地西泮进行平行对照实验，并进行了组方设计和实验。

Using HPLC separation and receptor binding assay, the present study demonstrated that the principle in the water extract of Huangqin acted on the BDZ binding site was not baicalin, wogonin or chrysin. In vivo study, WEH had no significant effect on pentylenetetrazol-induced clonic seizures in mice, although it could inhibitmaximal electroshock-induced tonic seizures with an ED50 of 3.6g/Kg.

本研究中，藉由高效率液相层析术与接受器结合实验评估，证实黄苓水抽提物中作用在BDZ结合处之主要成分，并不是黄苓甘、泛黄苓素或chtysin。

divided the people in early prenancy into two groups: observation group and control group, each group with 100 people. people in observation group were putted misoprostol 0.6mg in the posterior fornix 2 hours before induced abortion and surface anesthesia in the cervix when operation; people in control group accept traditional induced abortion. then compared the indexs about the extention degree of the cervix, abdominal pain, colporrhagia, operation time, completely abortion rate and adverse reaction after operation, et al.

将早孕患者随机分成观察组和对照组两组，每组100例，观察组人工流产术前2h将米索前列醇0.6mg放置阴道后穹窿，手术时行宫颈表面麻醉，对照组行传统人工流产术，比较两组流产过程中宫颈扩张难易程度，腹痛情况，阴道流血情况，手术时间，完全流产率及术后不良反应等指标。

There had been a moment during the breakfast meeting, though, after the backslapping and the small talk and when all of us were seated, with Vice President Cheney eating his eggs Benedict impassively and Karl Rove at the far end of the table discreetly checking his BlackBerry, that I witnessed a different side of the man.

那次早餐会期间，在表示过关心和寒暄以后，我们所有人坐了下来，我注意观察了一下，副总统切尼面无表情地吃着班尼迪克蛋（Eggs benedict，源自美国，以英式松饼、火腿、水煮蛋以及荷兰酱组合而成），卡尔。罗夫在餐桌的远端谨慎地经常查看他的黑莓手机，我目睹了他所不为人知的一面。

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