查询词典 induced draft

IM-induced autophagy did not involve c-Abl or Bcl-2 activity but was associated with ER stress and was suppressed by depletion of intracellular Ca2+, suggesting it is mechanistically nonoverlapping with IM-induced apoptosis.

IM诱导的自噬与c-Abl 或 Bcl-2活性无关，但与内质网应激相关并受细胞内Ca2+缺失抑制，提示其与IM诱导的细胞凋亡机制不同。

Bone marrow-derived mesenchymal stem cells are capable of chondrogenesis, making them a possible source of cells for injectable cartilage tissue engineering. There exist different ideas on the ability of mesenchymal stem cells's chondrogenesis in monolayer culture. Because of this, the effect of adult rabbit's bone marrow-derived mesenchymal stem cells chondrogenesis in monolayer culture was studied. The mesenchymal stem cells was isolated from adult rabbit's bone marrow and monolayer cultured. TGF-β1, Vit-C and Dexamethasone were used. Immunohistochemistry analyses and histological staining of H-E, Methylaniline blue and Alcian blue were performed to identify the expression of collagen type Ⅱ and cartilage associated matrix. The results showed that the induced cells expressed and produced collagen type Ⅱ and cartilage associated matrix. This suggests that the differentiation of adult rabbit's marrow-derived mesenchymal stem cells into chondrocyte in monolayer culture is feasible and may be induced by TGF-β1, Vit-C and Dexamethasone.

骨髓基质干细胞的软骨分化潜能使其可能成为可注射组织工程化软骨研究的种子细胞，为探讨体外培养的骨髓基质干细胞在平面诱导条件下软骨分化的可行性，我们进行下列实验：获取并体外平面培养成体兔骨髓基质干细胞，应用TGF-β〓、Vit-C和地塞米松对其软骨分化诱导，诱导后的骨髓基质干细胞行细胞爬片组织学和Ⅱ型胶原免疫组化，结果证实，诱导后骨髓基质干细胞可分泌Ⅱ型胶原，组织学染色可见类似于软骨细胞，由此证明体外培养的骨髓基质干细胞在平面诱导条件下可以软骨分化，其软骨诱导因子为TGF-β〓、Vit-C和地塞米松。

High dose copper induced decrease ofⅠ,Ⅱ,Ⅳ-2 content and increase ofⅢof spectrin. High dose copper can also decrease SA, PE content and increase SM, PS content.These showed that high dose can induce injury of erythrocyte by changing elementary structure and moity of membrane protein and membrane phospholipid, which may be one of the mechanisms of goat erythrocyte damage induced by high dose copper. 2. High copper caused the decrease of SOD and GSH-PX activity and the increase of MDA content.

高铜能引起红细胞膜收缩蛋白Ⅰ、Ⅱ及区带Ⅳ-2蛋白含量均显著降低，而区带Ⅲ蛋白含量明显增高，红细胞膜唾液酸含量降低，磷脂酰乙醇胺含量降低，神经鞘磷脂和磷脂酰丝氨酸含量升高，表明高铜能够改变红细胞膜蛋白和磷脂等基本结构和组成成分，这可能是高铜致羊红细胞损伤的机制之一。

No callus could be induced from leaf or petiole explants of varieties F30 and Ⅱ cultured on MS medium if supplemented alone with 6-bezyladenine （6-BA） or thidiazuron, or kinetin. However, the calli were induced on MS medium containing 2.0 mg L-1 6-BA and 0.5 mg L-1 NAA （α-naphthaleneacetic acid）, and the calli derived from petioles of variety Ⅱ could produce redifferentiated shoots, but of variety F30 could not. The later could only produce shoots directly from the base of the petioles.

将品种F30和Ⅱ的叶片和带叶叶柄接种到含不同浓度单一细胞分裂素（6-BA、TDZ、KT）的MS培养基上培养，均未能诱导出愈伤组织，而在含2.0mgL-1 6-BA＋0.5mgL-1 NAA的培养基上可以诱导出愈伤组织，且由品种Ⅱ叶柄诱导产生的愈伤组织可再分化出芽，品种F30诱导的愈伤组织却不能分化，但在其叶柄基部可直接出芽。

The aim of this brief review is to discuss the safe contrast administration in radiological examination process, including iodinated contrast medium induced extravasations, allergy, and nephrotoxicity via intravenous route; gadolinium induced nephrogenic systemic fibrosis, attention information on other contrast medium or medications.

本文将讨论放射线检查之用药安全流程，包括注射含碘对比剂造成渗漏、过敏或对比剂造成的肾毒性；注射含钆类对比剂发生肾因性全身纤维硬化症、其他对比剂或药物的注意事项。

Chapterl Establishment of the chronic and pressure-induced SD rat models for acoustic neurinomas Object To establish the chronic and pressure-induced SD rat models of acoustic neurinomas for the purpose of further experimental research on acoustic neurinoma related electrophysiology, function and pathomorphology of facial nerves and cochlear nerves.

第一章 SD大鼠听神经瘤慢性压力模型的建立目的建立SD大鼠听神经瘤慢性压力模型，为听神经瘤所致面、听神经电生理、功能及病理学改变的研究奠定基础。

It is therefore concluded that FA can directly activate a subpopulation of primary nociceptor cells and the FA-induced AP discharges are likely to contribute mainly to phase 1, but not phase 2 of the formalin-induced nociception.

以上结果提示，甲醛溶液选择性地激活一个亚群的初级传入伤害性感受器细胞，甲醛激活的动作电位的发放主要参与福尔马林诱发的第一相伤害性感受的产生。

The above results showed that physiological AAI pacing maintained a normal EAS and VAS, and improved or enhanced VSS; while nonphysiological VVI pacing and physiological DDD pacing induced the decrease in VSS due to an abnormal EAS and VAS. Furthermore, with increasing the pacing rate, VSS was markedly decreased.The quantitative comparison of parameters of left ventricular systolic function obtained by computerized ERNA showed that AAI pacing induced the significant increases in ventricular ejection rate and stroke volume with concomitant shortening of ejection time.

应用计算机-ERNA相位分析技术，对13例生理性AAI、13例非生理性VVI及6例生理性DDD患者，分别进行等相位电影，相位图，相位直方图和VSS参数的静动态观察和定量比较，结果显示：AAI起搏可维持正常EAS和VAS，心室相位均匀一致，并且VSS参数-相角程，半高宽和峰相位标准差均较起搏前分别降低，提示起搏后VSS有所改善或增强。

More importantly, blocking CPT-induced Noxa using specific siRNA significantly reduces the apoptosis response, indicating that Noxa is an essential mediator for CPT-induced apoptosis.

通过免疫共沉淀实验，我们证明了不管有没有CPT处理的情况下Noxa都可以和Mcl-1相互作用，说明Noxa和Mcl-1之间应该存在一个平衡，从而调节细胞凋亡。

TyPe II collagen induced arthritisln the rat ank1e joint andoVathumin as antigen induced arthritis WA in the rabbit knee joint wereestab1ish2 Qualitative evaluation of me in skin, muscle, synovium, cedilagearound joint and blood was performed by OMA3 The CIA rats were treated on day 7 after hind paw swelling and erythemaAnimals were injected intravenously with ase at a dose of 10mg/kg,tWenty minuots 1ater, one ankle of the rats random1y assigned was exPosedlaser irradiation at l00J/cm fOr l000 seconds, and another ankle wasM grouP wihout laser The other two groups is unmanipulatedcontrol group and untreated CIA group Bimaleolar ankle widthmeasuremellts were taken in all animals every tWo days using amicrometer The histopathology of the ank1e Joint was assessed at day 21after disease onset4 The pro1iferating cell nuclear antigen WCNA of CIA treated by PDT andthe HMME group without laser was doterdrined by immunohistochemiStry5 The AfA rabbits were treated on day 7 after knee swelling and erythemaThe theraPy invo1ved lntravenous injection of l0mg/kg HMME, fOl1owedby 20 minues period in dim light, and transdermal light treatment with\l00 J/cm2 fOr l000 seconds The inner sides of the treated Anees wereirradiated at first, and then the outer side did 24 hours later, the synovialtissue of the Anees joint were removed and in situ cel1 aPoptosis wasdetCCted With tednal deoxync1eotidyl transferase-mediated dUTP nickend labelingR6suIt8:l The pathologic changes of CIA and AIA include subsynovial inflammation,opovial hyPerplasia, pannus formation, cartilage and bone destructionresemble RA.2 The studies demonstrated that there are different uptake of HMME withinskin, muscle, synovium, cartilage and b1ood, and the synovium cou1draPidly uPtake more ase than skin and cartilage at the firSt 30 minuesaller intravenous injection of HMME3 The bimaleolar anke width had no different among PDT treated group,H group withollt 1aser and untreated CIA group But hlstologicalevaluation showed statiStical1y significallt reductions in synovialhyperplasia, pannus formation and cart1lage reosion, bone destruction andtotal score in PDT treated group4 Image analysis showed that the ratlo bforeen the areas of the coufltedobect to that of the entire area in PDTtreated grOup is lower than that in conirol group, but the integrated oPticaldensity had no different between the two groups5 Imape analysis showed that the ratio between the area of the countedobject to that of the e

治疗组在大鼠出现踝关节红肿后1周，炎症达到高峰时进行PDT治疗。随机治疗大鼠一侧的踝关节，另。2。一一侧作单纯HMME 对照。治疗方法是大鼠麻醉后尾静脉注入 HMME10ngkg，20分钟后踝关节照光，激光波长627.sum，功率密度 100mwcm'，照射时间1000秒，能量密度100）／。治疗后避光喂养72 小时。隔日一次测量大鼠的踝关节左右横径，治疗后两周取关节进行病理d 观察。 4。大鼠CIA模型用上述方法进行PDT治疗后，治疗组和单纯HMME 组用兔疫组化SP法检测石蜡切片的核增殖抗原。 5。兔AIA模型在关节炎出现第七天进行PDT治疗，随机治疗一侧膝关节，另一侧作自身对照。兔耳静脉注入I'arrainrelomg／Kg，20分钟后，膝关节用金蒸气激光照射，激光能量密度100）儿旷。24 ／J'时后取膝关节滑膜作病理检查，并用脱氧核昔酸末端转移酶介导的缺口末端标记法原位检测凋亡细胞。结果： 1。模型观察：CIA大鼠炎症高峰期滑膜下炎细胞浸润明显，滑膜细胞明显增殖，炎症达到高峰后二周，血管缀形成，并侵蚀和破坏软骨和骨， CIA模型病理改变与人类RA相似。兔AIA模型膝关节滑膜病理可见滑膜细胞增生，滑膜下炎细胞浸润，也与人类RA滑膜改变相似。 2。关节周围组织中光敏剂含量的测定结果表明，各组织对HMME 的吸收速度和吸收量不同，荧光值一时间曲线不同，滑膜组织比皮肤和软骨对 HMME的吸收多，在 2 0分钟时即有明显差异。 3.PDT对CIA模型的治疗结果表明：PDT治疗后关节炎组、单纯 HMME组和治疗组踝关节左右横径统计学检验差异没有显著性，但病理评分PDT治疗组滑膜增生、血管资形成及软骨破坏、骨破坏和总分比关节炎对照组和HMME对照组好，统计学检验差异有显著性。。3＿军医进修学院硕士学位论文中文摘要 4.PDT治疗组PCNA阳性细胞较对照组少，图像分析结果表明面密度（阳性染色的面积总和与统计视野面积的比值）治疗组小于对照组，统计学检验差异有显著性。。 5.PDT治疗组凋亡阳性细胞较对照组明显增多，图像分析结果单位视野内阳性细胞数和面密度PDT治疗组高于对照组，统计学检验差异有显著性。凋亡细胞核直径PDT治疗组较小，与对照组相比，统计学检验差异有显著性。结论：二。CIA、AIA的病理改变类似人类RA，可作为研究RA病因、发病机制、检查及治疗方法的模型。 2。各组织对HMME的吸收速度和吸收量不同，滑膜组织比皮。

There are different types of personal loans available.

有许多不同类型的个人贷款优惠。

The above mentioned teaching model of spiral rising can be used to avoid rigidness in teaching.

上述螺旋式上升的教学模式，可以避免教学形成模式後的僵化现象。