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Part I Role of glycogen synthase kinase 3 in squamous differentiation induced by cigarette smoke in porcine airway epithelial cell Squamous differentiation of airway epithelium induced by diverse stimuli, such as cigarette smoke, has been thought to be an adaptive response to chronic injury as well as a precancerous lesion of lung squamous carcinoma.

第一部分糖原合成酶激酶3在吸烟诱导的猪气道上皮细胞鳞状分化中的作用研究气道上皮的鳞状细胞化生常见于慢性支气管炎症、致癌剂刺激等，一般被认为是对慢性损伤的一种适应性反应，也是肺鳞癌的癌前病变，其分子机制尚未完全阐明。

The injury of stomach mucous membrane induced by alcohol and acute gastritis induced by sodium salicylate in rats were observed.

结果陈香露白露胶囊 0 。6g kg和 1.2g/kg均能明显降低乙醇致胃粘膜损伤和水杨酸钠诱发的急性胃炎的溃疡指数，0 。3g/kg、0 。6g/kg和 1.2g/kg均可明显降低醋酸所致小鼠发生的扭体反应次数。

BSpatial characterization of laser induced Cu plasma in air with different laser focusing distancesThe plasma spectra induced by pulsed laser ablation of copper target are measured. By adjusting the distance of the len-sample, the spectrum of air spark plasma、 Cu plasma and the reciprocity of both plasmas are analysed. From the result, it has been shown that the focusing of the laser beam has an important infunence to analyse the properties of the sample.

b 不同的激光焦点位置产生的等离子体光谱的空间特性研究激光烧蚀置于空气中的Cu靶产生等离子体，通过调节透镜与Cu靶的距离，本文观测了激光烧蚀空气产生的空气火花等离子体、激光直接烧蚀铜靶产生Cu等离子体以及空气火花等离子体与Cu等离子体相互作用等不同情况下的激光诱导击穿发射光谱，激光束焦点的位置在分析材料性质的过程中有着重要的影响。

To research the relation of oil's laser induced fluorescence intensity and oil temperature, the third(355nm) harmonics pulsed Nd: YAG laser was used as the exciting source, and a multi-track spectrology as the detector, and the intensities of laser induced fluorescence of oil under different temperatures were measured.

研究一种应用较广的油的激光诱导荧光强度与其本身温度之间的关系。用输出波长为355nm的三倍频Nd：YAG激光器做激发光源，用多通道光谱分析仪进行接收探测。

In our islet transplantation program nonhuman primates with STZ-induced diabetes received transplants under chronic immunosuppression including calcineurin inhibitors, drugs in the rapamycin class affecting growth factor-induced cell proliferation, and the sphingosine 1-phosphate receptor antagonist FTY720. Four animals developed renal failure and had to be sacrificed, most likely caused by cyclosporine.

在我们应用STZ诱导的糖尿病的灵长类动物性胰岛细胞移植的病例长期应用的免疫抑制剂包括：钙神经素拮抗剂，雷帕霉素和神经鞘氨醇1－磷酸盐FTY720.4个动物死于肾功能衰竭，这很可能是由于环孢素引起的。

Furthermore, in the CTA rats, compared with water stimulability, FLI neurons of SON and DMV induced by sucrose stimulability had had much more expressions.6 When the same sucrose stimulability was given, FLI neurons expressions of SON, DMV and LH in the CTA rats were much lowwer than that in the control rats.Conclusions:1 CTA had an inhibitory effect on small intestine peristalsis, indicate taste preference has an effect on small intestine peristalsis, and inhibitory effect induced by CTA is corresponded with US, this effect may have relations with vagus efferent never and humoral regulation.2 In the electrophysiology experiment, discharges of vagus efferent never in the CTA rats are much more than that in the control rats, indicates taste and taste preference may regulate small intestine peristalsis via vagus nerve, and dicharge can continude 1 hour, indicate humoral regulation also exists in the regulation.

结论1建立味觉厌恶对小肠运动有抑制作用，提示味觉嗜好性对小肠运动有影响，而且味觉厌恶引起抑制作用是与条件刺激成对应关系的，味觉刺激引起的小肠蠕动的抑制作用可能与迷走神经传出神经及体液调节有关。2在电生理实验中，CTA大鼠迷走神经传出放电高于对照组的大鼠，提示味觉及味觉嗜好性可能是通过迷走神经对小肠运动进行调节的，放电至能持续60min，表明味觉及味觉对小肠运动的调节中还有体液调节的参与。

When EGTA (Ca〓 chelator), Verapmil and LaCl〓(Ca〓 channel blockers) were used to treat tomato fruit at green mature and strawberry fruit at white stage with ethylene, they could reverse ethylene-induced increase in ethylene production in tomato and strawberry, PG activity, lycopene content, soluble protein content in cell wall in tomato and degradation in soluble protein in strawberry, which indicated blocking Ca〓 channel in plasma membrane or chelating Ca〓 can decrease intracellular Ca〓, further inhibite ethylene-induced maturation, ripening and senescence of fruit.

用质膜钙通道阻断剂异博定、钙通道Ca〓竞争性抑制剂以及Ca〓专一性螯合剂与乙烯一起处理绿熟期番茄果实和乳白期草莓果实，均可抑制乙烯诱导番茄和草莓的乙烯生成、番茄PG活性的提高、番茄红素含量的增加和细胞壁可溶性蛋白含量的增加以及草莓可溶性蛋白的分解，表明阻断质膜Ca〓通道或螯合胞外Ca〓以减少胞内Ca〓能抑制乙烯对果实的催熟作用，间接证明乙烯对果实成熟衰老的诱导与胞外Ca〓内流引起的胞质Ca〓浓度的增加密切相关，表明乙烯信号转导可能与钙信使有关，调节胞质Ca〓浓度可调节乙烯对果实的催熟作用。

According to analysis of root exudates by HPLC, aluminum induced roots of stylo to secret citrate and its secretion increased with Al concentration treated (0, 10, 20, 50 umol L-1) and the period of exposure to Al (6, 12, 18, 24 h), which indicated that Al-induced secretion of citrate is an important mechanism for stylo to resist the toxicity of aluminum.

采用高效液相色谱法对根系分泌物的分析发现，铝诱导柱花草根系分泌柠檬酸，并且其分泌量随铝处理浓度0、10、20、50 μmol L~(-1和时间(6、12、18、24 h)的增加而增加，表明铝诱导根系分泌柠檬酸是柱花草抵御铝毒害的重要机制。

Effects of Adv-hBMP2 gene modify on the bone formation of tissue-engineered bone substitute. BMSCs of canine transferred by Adv-BMP2 gene expressed ALP in vitro and induced ectopic bone formation in nude mice. BMSCs adhered on the surface of FDB after 4hrs, expanded in 24hrs and proliferated in polylayer in 4d. FDB, combined with BMSCs transferred by Adv-BMP2 gene, induced bone formation in the subcutis of nude mice in 6 weeks.

结果：1.BMP-2基因修饰对组织工程化骨成骨的影响 BMSCs经Adv-BMP2基因转染后ALP染色强阳性、并在裸鼠肌肉形成异位骨组织；转基因的BMSCs与冻干骨复合后24小时即完全贴附生长，4天后复层生长并分泌大量胶原，植入裸鼠背部皮下6周后可见大量成骨，很少吸收，而单纯冻干骨或冻干骨复合BMSCs基本不成骨。2。

Subtle changes, such as oxidative damage-induced loss of glutamine synthetase activity, may be a key event in stroke-induced brain injury.

一些细微的变化，比如氧化损伤诱导的谷氨酰胺合成酶活力丧失，可能是中风引起的脑损伤的关键环节。

There are different types of personal loans available.

有许多不同类型的个人贷款优惠。

The above mentioned teaching model of spiral rising can be used to avoid rigidness in teaching.

上述螺旋式上升的教学模式，可以避免教学形成模式後的僵化现象。