黄疸

The basis of pathology of VOD is thought resulting from injury of hepatocytes and endodermis cells surrounding the central veins in zone 3 of the liver acinus by regimen-related toxicity.

一般发生在移植预处理后3周以内，多数在移植后1~2周，临床以肝肿大、黄疸、体重增加、腹水、水液潴留、丙氨酸氨基转移酶增高等为主要表现，发生率5%~60%[1，2]。

Conclusion. A UTI was found in 7.5% of asymptomatic, afebrile, jaundiced infants younger than 8 weeks old.

结论。 7.5%的无症状的、无发烧的、黄疸的婴儿（小于8周龄）是有尿路感染的。

Results Internal jaundice was found in 63 cases (acute hepatitis in 40 cases, chronic hepatitis in 4 cases ,cirrhosis with ascites in 7cases ,cirrhosis with hepatic cancer in 4 cases, acute bacterial cholangitis in 1 case and acute calculous cholecystitis in 7 cases). Surgery jaundice in 21 cases (common bile duct stone in 9 cases, cholangiocarcinoma in 3 cases, pancreatic head cancer in 4 cases, focal pancreatitis in 1 case, ampullar carcinoma in 2 cases and biliary duct distal obstruction in 2 cases).

结果：内科性黄疸63例（急性肝炎40例，慢性肝炎4例，肝硬化伴腹水7例，肝硬化伴肝癌4例，急性细菌性胆管炎1例，急性结石性胆囊炎7例），外科性黄疸21例（胆总管结石9例，胆管癌3例，胰头癌4例，胰头炎症1例，壶腹癌2例，胆总管末端梗阻性病变2例）。

AIM: To investigate the influence of lactulose and glutamine on the changes of jejunal mucosal morphology of rats with obstructive jaundice.

摘要目的：研究梗阻性黄疸时空肠黏膜的变化及lactulose 和 glutamine对梗阻性黄疸大鼠空肠黏膜的影响。

Results Perinatal factor 66 cases,mother milk jaundice 46 cases,germs infection 37 cases,hemolytic disease of the newbron 14 cases,hypercythemia of the newbron 32 cases,hepatitis synd...

结果 围产因素 66例，母乳性黄疸 46例，细菌感染 3 7例，新生儿溶血症 14例，新生儿红细胞增多症 3 2例，肝炎综合症 2例，先天性胆道阻塞 1例；黄疸程度与病因有关，不同病因与治疗所需时间有所不同；除死亡 2例和放弃治疗 6例，其余患儿均痊愈出院。

Jaundice, serum bilirubin is the depth of the neonatal period caused by the symptoms caused by increased and not have to worry about, most children will be out of jaundice, but there is light there is heavy, some obvious and some more than obvious.

黄疸，是新生儿时期血清胆红素深度增高引起的症状造成的，不用担心，大多数孩子都会出黄疸，只是有轻有重，有的明显有的不明显而已。

The beginning of the two easily confused, but has a history of exposure to hepatitis, after dynamic observation, jaundice early serum aminotransferase increased, jaundice more than 2 ~ 3 weeks after the station began to dissipate, serum alkaline phosphatase values do not rise.

初起两者易混淆，但肝炎有接触史，经动态观察，黄疸初起时血清转氨酶增高，黄疸多在2～3周后逐渐消退，血清碱性磷酸酶多不高。

The difference was significant.Conclusions The concentration of serum TNF α was higher,and this can play a important role in the pathogenesis of the complications after BDL.

梗阻性黄疸后TNF升高是导致机体一系列病理改变的关键性炎症介质，口服乳果糖可降低循环中TNF浓度，且能缓解梗阻性黄疸后所产生的并发症。

Results Total bilirubin, Direct bilirubin increased significantly. In BDL rat liver, the membrane protein MRP2 expression was significant down-regulation and no nuclear receptor FXR was expressed.

结果 梗阻性黄疸大鼠总胆红素、直接胆红素显著升高；与假手术对照组相比，梗阻性黄疸组大鼠肝细胞MRP2蛋白表达明显降低(P=0.041)，FXR蛋白无表达，差异均有统计学意义。

The protein expressions of MRP3 and Lrh-1 were determined with Western blotting. Results Total bilirubin and direct bilirubin increased, but albumin decreased. In BDL rat liver, the membrane protein MRP3 and Lrh-1 expression were all significantly up-regulated.

结果 梗阻性黄疸大鼠总胆红素、直接胆红素显著升高，白蛋白显著降低；与假手术对照组相比，梗阻性黄疸组大鼠肝细胞MRP3和Lrh-1蛋白表达明显升高(P值分别为0.027和0.046)，差异有统计学意义。

He and Nina moved to California and lived at 2005 Ivar Street, Apt.

他和Nina搬到加州，并在2005年伊瓦尔街，公寓生活。

Droperidol （ potently inhibits transfected HERGchannels and this is the probable mechanism for QT prolongation.

氟哌利多有效地抑制了转染的 HERG 钾通道，可能是 QT 间期延长的机制。