致癌基因

For some dyes, the dye concentration of less than 1ppm in receiving water bodies is highly visible, so that even small quantities of dyes can color large water bodies. This not only affects aesthetic merit but also reduces light penetration and hydrophyte photosynthesis. In addition, some dyes or their metabolites are either toxic or mutagenic and carcinogenic.

某些染料在浓度低于1ppm时就能使接受水体明显着色，所以即便是少量的染料也会污染大面积水体，这不仅影响了水环境的美观而且会减少水体透光量，进而影响水生植物的光合作用，况且，有些染料或其降解产物有毒，甚至能诱发基因突变或致癌。

Objective To explore the effect of p16 gene on the growth inhibition of esophageal carcinoma cell line NEC.

目的 探讨p16基因对食管癌细胞生长的抑制作用，为食管癌致癌机理的研究和基因治疗提供理论基础。

The carcinogenic mechanism of nitrosamine is that it may cause the changes of tumor related gene and suppressor gene in esophageal epithelisl cells.

其致癌机制研究显示，亚硝胺可引起食管上皮细胞相关癌基因抑癌基因发生改变，大大促进癌变。

We are interested in studying gene regulatory events in the immune system, with an emphasis on plasma cell differentiation and neoplastic transformation of plasma cells.

我们的研究兴趣在於探讨免疫系统的基因调节，目前著重於了解浆细胞的分化及其相关肿瘤的致癌过程。

Safrole is genotoxic and carcinogenic in laboratory animals, and these effect is mediated through the 2-step bioactivation of safrole by cytochrome P450 and sulfotransferase to stable safrole-DNA adducts.

实验证明此黄樟素DNA键结物对实验动物具有基因毒性及致癌性，而本实验室已能自口腔癌患者的口腔组织侦测到黄樟素DNA键结物之存在。

Furthermore, besides considering changes in DNA methylation as mechanisms of disease, the role of epigenetics in general and DNA methylation in particular in transgenerational carcinogenesis, in memory formation and behavior establishment are brought about as mechanisms based on the cellular memory of gene expression patterns.

而且，除了考虑DNA甲基化改变作为疾病的机制外，表观遗传学一般的及DNA甲基化特别的在隔代致癌中的作用，在记忆形成和行为确立被引发作为基于基因表达模式的细胞记忆的机制。

Expression of mutant tumor suppressor gene p53 in egg-type chicken with avian leukosis subgroup J was detected to study cancericidally molecular mechanism of ALV-J. Using immunohistochemistry method of strep avidin-biotin complex, many organs of illed egg-type chickens, involved liver, kidney, ventriculus glandularis, tumor, heart, pancreas, bone marrow, spleen, oviduct, lung, duodenum, thymus and bursa of fabricius were studied.

为了探讨J亚群禽白血病病毒的致癌分子机理，观察蛋用型鸡发生J亚群禽白血病时p53抑癌基因在各脏器中的表达，应用链霉亲和素-生物素-过氧化物酶复合物免疫组化法，研究了蛋用型鸡J亚群禽白血病自然病例的肝脏、肾脏、腺胃、肿瘤、输卵管、心脏、胰脏、骨髓、脾脏、肺脏、十二指肠、胸腺和法氏囊。

Our results showed that NAT2 slow acetylator genotype was a significant susceptibility risk factor to Chinese breast cancer patients in Taiwan.

1.83， p=0.046。。总结而言，针对台湾地区的华人，NAT2 代谢速率慢者之基因型为罹患乳癌之显著的致癌感受性危险因子。

Objective Applying randomized terminal linker-dependent PCR to detect the DNA damage of ras gene induced by dichloroacetic acid.

目的研究二氯乙酸(dichloroacetic acid，DCA)对ras基因的DNA损伤作用，探讨其致癌作用分子机制。

Specific siRNA was used to target LMO2 in Molt-4 cells. Results Higher expression of LMO2 was detected in some of patients with acute myeloblastic leukemia or acute lymphoblastic leukemia. However, enforced expression of LMO2 in K562 cells decreased cellular clonogenecity, suggesting the activation of the gene may not be important in the pathogenesis of myeloid leukemia.

结果 LMO2基因在很多急性髓系和淋巴系白血病患者的表达水平高于慢性白血病患者及正常骨髓细胞，但LMO2转染的K562细胞克隆形成率下降，提示该基因在髓系白血病细胞的表达异常是一种伴随结果而不具有致癌作用。

The reasons of iron ions content overproof in grade Ⅱ desalting water system,such as variation water quality,contamination of regenerant , operation adjustment of pretreatment system and switching operation of bed were discussed.

对二级脱盐水系统中铁离子含量超标的原因，如来水水质发生波动、再生剂受到污染、预处理系统操作调整、床体运行切换等进行了论述。

You were hired to drum up new business, so go and do it.

公司雇你招徕新业务，你就做你的事好了。