致癌基因

Oncogenic transformation of c-abl to v-abl occurs by insertional activation that results in deletions of specific N-terminal amino acids.

由abl癌基因编码的转化蛋白。c-abl到v-abl的致癌性转化由于插入激活而发生并引起特异性氨基末端氨基酸删除。

Most importantly, we show that corrected Fanconi-anaemia-specific iPS cells can give rise to haematopoietic progenitors of the myeloid and erythroid lineages that are phenotypically normal, that is, disease-free.

血液疾病有可能成为基因修正疗法的第一目标，因为这些修正细胞可经骨髓移植很容易地植回患者体内。但在利用iPS源性细胞进行任何临床试验前都必须解决一些严重相关的问题，其中最重要的就是致癌问题。

In the present study, we applied water-insoluble nickel oxide and nickel subsulfide to induce morphological transformation of human embryonic lung cells and to probe the differentially expressed genes related to the transformation.

因此本研究试图用两种水不溶性镍化合物诱发人胚肺细胞的恶性转化模型，并分离、克隆与之相关的差异表达基因，为深入研究镍致癌的分子机理提供初步的资料。

It was known that many mutagens also exert the effect of carcinogenesis.

许多证据显示，致基因突变与致癌反应之间有著密不可分的关系。

Compared to traditional mutagens, the cell fusion caused by tumor viruses can reasonably explain many phenomena found in some virus-associated cancers.

相对于基因突变等细胞癌变的传统诱因，病毒的这种致癌机制能够更合理地解释我们在癌症中发现的许多现象。

It has been demonstrated that MITF is an amplified oncogene in a fraction of human melanomas and that it also has an oncogenic role in human clear cell sarcoma.

已经证明， MITF是一种原癌基因扩增的一小部分人的黑色素瘤，它也有致癌作用，人类透明细胞肉瘤。

The study on themechanisums has been a hotspot of biology and radiobiology.

值得关注的是，自从国外学者提出电离辐射旁效应概念以来，许多研究者证实旁效应的存在，对&照射细胞核才会引起细胞致命的损伤&&只有受照射细胞才受到损伤&等某些传统观念提出了有力的挑战，辐射诱导的基因不稳定性、细胞质受到照射所致的突变及旁效应等在辐射致癌中同样具有重要作用，并得到放射生物学界的确认。

I'm strongly against the death penalty — it's an eye for an eye.

我不赞成死刑——这是以牙还牙的报复行为。

And to get you the support you need, we're enlisting all elements of our national power: our diplomacy and development, our economic might and our moral suasion, so that you and the rest of our military do not bear the burden of our security alone.

并给你们所须的支援，我们正徵召国家所有各种的力量：我们的外交及发展，我们的经济力量与道德劝说，所以你们与其他军人不须要孤独地负起国家安全的责任。