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In experimental study,we choose healthy Wistar mice to make models of bronchial asthma in catabasis,we observe the influence on inflammatory factor and immunological factor in air-way、bronchial and pulmonary pathology after drench.

实验研究选择健康Wistar大鼠制作哮喘缓解期模型,观察防哮合剂灌胃后对气道炎性因子、免疫因子及支气管和肺脏病理学的影响,并与酮替芬阳性对照组比较。

In experimental study, we choose healthy Wistar mice to make models of bronchial asthma in catabasis, we observe the influence on inflammatory factor in air-way、bronchial and pulmonary pathology after drench concentrated solution of FXG.

实验研究选择健康Wistar大鼠制作哮喘缓解期模型,观察防哮颗粒浓缩液灌胃后对气道慢性炎症及支气管和肺脏病理学的影响,并与酮替芬阳性对照组比较。

Healthy Wistar Rats were chosed to make models of remission stage of asthma,the influence on inflammatory factor and immunological factor in air-way、bronchial and pulmonary pathology after treating with Fang Xiao Mixture were observed,and compared with ketotifen group.

选择健康Wistar大鼠制作哮喘缓解期模型,观察防哮颗粒对模型大鼠气道炎性因子、免疫因子及支气管和肺脏病理学的影响,并与酮替芬阳性对照组比较。

The experimental study shows that the FXG can reduce the content of inflammatory factor IL-4 in the serum of bronchial asthma mice in catabasis, and EOS count in the peripheral blood of it, restrain the collection of EOS in bronchi and lung, alleviate air-way tracheospasm and have evident differences compared with ketotifen group.

实验研究结果显示:防哮颗粒能降低哮喘缓解期模型大鼠血清中炎性因子IL-4的含量,明显改善哮喘模型大鼠外周血中EOS计数的异常升高。能抑制支气管和肺脏局部EOS聚集,减轻气道炎性损伤,轻模型大鼠肺组织的病理改变。

FXG can reduce the content of inflammatory factor TNF-αand immunological factor IgE in the serum of bronchial asthma children in catabasis, restrain the collection of EOS in bronchi and lung, restrain the inflammation in air-way and alleviate air-way straitness;improve the level of serum IgA、IgG、IgM and CD3、CD8,enhancing the immune functiong of bronchial asthma children.

结果:防哮颗粒的总有效率为93.33%,在减轻患儿主要症状、体征,减少感冒次数、咳喘天数,改善肺循环方面优于两对照组;在改善肺功能方面与普米克都保的疗效无差别,而明显优于固本咳喘片(P.01);并能降低哮喘缓解期儿童血清中炎性因子TNF-α、免疫因子IgE的含量,抑制支气管和肺脏局部EOS聚集,抑制气道变应性反应,减轻气道狭窄;提高IgA、IgG、IgM水平及CD3、CD8含量,增强患儿免疫力。

The serum contents of IL-8, TNF-a, MDA ,lactic acid ,sICAM-land the myeloperoxidase in lung were remarkedly decreased in rats which were administrated by UTI. the D/W of lung and liver was decreased too. All of this demonstrate that Ulinastatin is beneficial in the severe thermal injury, which is helpful to the relief of MODS.

其结果显示在严重烧伤大鼠应用乌司他丁后,血浆中TNF-a、IL-8的含量、肺脏与肝脏的干湿重比、血清的乳酸与丙二醛含量以及sICAM-1含量,肺脏中的MPO含量,均明显降低,表明乌司他丁可能有助于减少或减轻对于严重烧伤后的SIRS/MODS的发生。

The correlation analysis between the lung model's CT volume value and the actually perfusing volume suggested that they were highly correlative, i.

肺脏模型体积CT测值与实际注水量的相关分析表明,肺脏模型体积CT测值与实际注水量高度相关。

The correlation analysis between the lung model's CT volume value and the actually perfusing volume suggested that they were highly correlative, i.e.

肺脏模型体积CT测值与实际注水量的相关分析表明,肺脏模型体积CT测值与实际注水量高度相关。

In malignant room skin tumour early phase can see something without the aid of instruments in regular or opaque dirty tier or wall have a lot of white or the gray pellet and form festival or the lamina on tier of pleurae Piece with the development of tumour change thickly long and change thickly long full pleura surface tubercle the tumour tubercle stretches room skin to all sides postpone continuing becoming movie cyst lungs uses the person The cellar is getting smaller as shrinking more and makes to be put into much trouble inclining a chest wall subside.

在恶性间皮瘤早期,肉眼可见在正常或不透明的脏层或壁层胸膜上有众多白色或灰色颗粒和结节或薄板块,随着肿瘤的发展,胸膜表面愈来愈变厚,长满结节,间皮瘤结节向四方伸延,连续成片,包囊肺脏使其窖越缩。。。在恶性间皮瘤早期,肉眼可见在正常或不透明的脏层或壁层胸膜上有众多白色或灰色颗粒和结节或薄板块,随着肿瘤的发展,胸膜表面愈来愈变厚,长满结节,间皮瘤结节向四方伸延,连续成片,包囊肺脏使其窖越缩越小

In histopathology sections showed that alveoli were complete and clear with walls being thin and brittle. In experimental group, some petechia were observed in lung samples , the area of fibroblast and fibrinogen in histopathology sections were found , and the ground-glass predominance and reticulation structure in Micro-CT findings were increased during the period from the 1st week to the 3rd week, and degrade in the 4th week after the administration.

结果显示,控制组之肺脏检体色泽正常,没有出血,组织病理学则以I型肺泡细胞为主,无间质性肺炎且肺泡完整清净,肺泡壁薄而完整;实验组方面,第一~三周肺脏检体外观及组织病理的呈现出血点及出血病灶且越趋严重,第四周则消退,且Micro- CT影像评估亦相同。

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