肌动蛋白

The change of actin is similar to that of myosin.

肌动蛋白也表现了相同的病理变化过程。

However, as a part of PICs, the role of actin in this complex remains to be elucidated.

但肌动蛋白在此复合物中的作用还有待于进一步研究。

A number of studies have suggested a role for actin in transcription.

越来越多的证据表明肌动蛋白也能参与基因转录的调控。

Objective:Microfilament is one component of cytoskeleton , and it is mainly composed of actin.

背景和目的：微丝是细胞骨架的成分之一，主要由肌动蛋白组成。

Kelch-like ECH-associated protein-1 (Keap1) normally sequesters Nrf2 in the cytoplasm in association with the actin cytoskeleton, but upon oxidation of cysteine residues Nrf2 dissociates from Keap1, translocates to the nucleus and binds to ARE sequences leading to transcriptional activation of antioxidant and phase II detoxifying genes.

在正常情况下，Kelch样环氧氯丙烷相关蛋白-1 (Kelch-like ECH-associated protein-1， Keap1)可将Nrf2与肌动蛋白细胞骨架一起收集在细胞质内，但是在半胱氨酸残基发生氧化的情况下，Nrf2和Keap1脱离，进入细胞核并与ARE结合，从而激活多种抗氧化基因和II相解毒基因的转录。

Kelch-like ECH-associated protein-1 (Keap1) normally sequesters Nrf2 in the cytoplasm in association with the actin cytoskeleton, but upon oxidation of cysteine residues Nrf2 dissociates from Keap1, translocates to the nucleus and binds to ARE sequences leading to transcriptional activation of antioxidant and phase Ⅱ detoxifying genes.

在正常情况下，Kelch样环氧氯丙烷相关蛋白－1(Kelch-like ECH-associated protein-1， Keap1)与Nrf2耦联，并与肌动蛋白细胞骨架结合被锚定于胞浆，但是在半胱氨酸残基发生氧化的情况下，Nrf2和Keap1解耦联，进入细胞核并与ARE结合，从而激活多种抗氧化基因和Ⅱ相解毒酶基因的转录。

A new expression vector with the promoter of the medaka β-Actin promoter and green-fluorescent protein gene was constructed based on Nde I site of pBluescript SK+.

从载体pBluescript SK+的Nde I位点处插入外源基因片段，构建了含有青鳉β-肌动蛋白启动子和绿色荧光蛋白标记基因的新表达载体。

Among seven different constructions we examined, a DNA fragment, named pCMV-MB-EGFPITR, containing EGFP reporter gene driven by human cytomegalovirus promoter and medaka β-actin promoter, produced the most intense GFP expression.

在我们试验的七个不同构筑质体中，被命名为pCMV-MB-EGFPITR的DNA片段，含有被人类巨细胞病毒启动子和稻田鱼β型肌动蛋白启动子所驱动的增强型绿萤光蛋白报导基因，能产生最强的绿萤光表现。

We employed a cell line of mouse podocytes immortalized with the simian virus 40 large tumor antigen gene, and examined the cell proliferation using colony-forming and MTT assays following treatment with various concentrations of bFGF. BMP-7, alpha-smooth muscle actin e podocytes were detected by western blot. Methyl blue staining was used for the observation of cell morphology.

利用SV40肿瘤抗原转染所获得的永生性小鼠足细胞系培养，以集落形成法和噻唑蓝MTT还原实验测定不同浓度bFGF刺激下的足细胞增殖，采用SDS-聚丙烯酰胺凝胶电泳和Western blotting 检测BMP-7、alpha-平滑肌肌动蛋白、以及波形蛋白的蛋白质水平表达，同时以甲基兰染色观察细胞形态。

There is an increasing need to better understand the fate of domoic acid, in aquatic ecosystem. In this report, partial cDNA of hepatic cytochrome P-450 1A (CYP1A), giutathione S-transferase alpha, glutathione S-transferase rho, heat shock protein 70 (HSP70), Na~+/K~+-ATPase alpha 1(ATP 1A1) and beta-actin gene from rabbitfish were obtained by PCR using degenerate primers, which respectively were 900 bp, 582 bp, 615 bp, 660 bp, 749 bp and 554 bp in length.

本研究成功克隆了黄斑篮子鱼肝脏第Ⅰ时相去毒酶细胞色素P450 1A，第Ⅱ时相去毒酶谷胱甘肽S-转移酶alpha和谷胱甘肽S-转移酶rho(GS7R)，热休克蛋白70(HSP70)，钠钾ATP酶alpha 1(ATP1A1)和β-肌动蛋白基因的核心序列，它们分别长900 bp，582 bp，615 bp，660 bp，749 bp和554 bp。

Since historical times,England ,where the early inhabitants were Celts, has been conquered three times .

从有历史以来，英国，在此地早期居住的是凯尔特人，已经被征服了三次。

Bluetooth OBEX File Transfer Enables the sending and receiving of files on your phone via Bluetooth.

蓝牙OBEX文件移动允许经过蓝牙传送和接受文件。。。。