空化

Barrett's metaplasia, gastroesophageal reflux, hiatal hernia, and obesity are thought to play a role in these cases.

Barrett食管化生，胃食管返流，食道裂空疝，和肥胖都被认为与此相关。

Results CsA clearly decreased creatinine clearance and increased urinary excretion of N-acetyl-β-D-glucosaminidase in rats as compared with those in the vehicle group. Morphologic changes consisted of vacuolization of tubular cell, expansion of the interstitium and interstitial fibrosis, hyalinization of afferent arterioles. Severity of the injury was related to the dosage of CsA. Striped interstitial fibrosis and arteriolopathy were more severe in the rats treated with CsA and low-salt diet than with CsA and normal diet.

结果 用CsA的大鼠出现尿量增多、内生肌酐清除率下降、尿N-乙酰-β-D-氨基葡萄糖苷酶排泄增多等；病理上表现为不同程度的细胞浊肿、空泡变性及灶性分布的间质纤维化和小动脉病变，随CsA剂量的增加，病变呈加重趋势；结合低钠饮食，CsA慢性肾毒性病变明显加重。

Based on this,We designed a series of experiments to study the treatment and its mechanism of Iridoids composition of Valeriana jatamansi Jones of the IBS animal model.1 Research on Iridoids composition of Valeriana jatamansi Jones in the role of gastrointestinal function.1.1 Effection of Iridoids composition of Valeriana jatamansi Jones on gastrointestinal function of normal miceMethods:Compared with normal group and YJBH group,mice which has given Iridoids composition of Valeriana jatamansi Jones as 71.2mg/kg,35.6mg/kg,17.8mg/kg,8.9mg/kg was detected gastric emptying and small intestinal propulsion after 4 days drug given.Results:Compared with normal group,gastric emptying and small intestinal propulsion in 35.6mg/kg and 17.8mg/kg group was inhibited.

课题通过观察蜘蛛香环烯醚萜对正常及IBS模型动物的胃肠道功能、精神活动的影响，以及蜘蛛香环烯醚萜干预下IBS大鼠结肠、血清、中枢5-HT含量，结肠5-HTR3A受体的mRNA和色氨酸羟化酶(TPH1)的mRNA表达，结肠和血浆中SP和VIP含量以及结肠中肥大细胞分布，探讨蜘蛛香环烯醚萜对腹泻型IBS的治疗作用及其作用机理，为临床治疗IBS提供实验依据。1蜘蛛香环烯醚萜对胃肠功能的作用目的：探讨蜘蛛香环烯醚萜对胃肠功能的影响1.1蜘蛛香环烯醚萜对正常小鼠胃肠功能的作用方法：正常小鼠灌胃给予蜘蛛香环烯醚萜71.2mg/kg、35.6mg/kg、17.8mg/kg、8.9mg/kg与空白组和越鞠保和丸组对照，给药4日后测定动物的胃排空率和小肠推进率。

Result In comparison with the control group, various degrees of empty osteocyte lacunae appeared in all 30 samples from the experimental group.

结果］与对照组相比，30例标本中均可见不同程度的空骨陷窝化。

Morphologically, the macrophages treated with NO and O-LDL presented shrinkage, nucleus fragmentation, and cytoplasm condensation; DNA ladder was visualized by agarose gel electrophoresis; Characteristic apoptosis peak of macrophages was showed by flow cytometry; Ultrastructure, The chromatin condensed and marginated to form dense chromatin fragmentation; The cytoplasm concentrated and vacuolized; The lysosomes and mitochondria of apoptosis macrophages increased clearly.

电镜观察超微结构变化：染色质固缩边聚，形成致密、均质的染色质块，胞质浓缩、电子密度升高并空泡化；凋亡巨噬细胞溶酶体、线粒体增多；细胞突起缩短减少，但巨噬细胞特有的板状伪足不消失。

Cytolysosomes increased,cellular nucleus became twisted,rough endoplasmic reticulums swelled,and chondrosome became vacuolization.Dead intervertebral disk cells were located in ?nidi? which were made of multilayer degenerative collagen fibers.

术后8周实验组椎间盘开始出现大量死亡细胞，表现为溶酶体明显增多，细胞核扭曲，粗面内质网扩张，线粒体空泡化，死亡细胞外周的&巢&增厚呈多层排列，致密颗粒增多。

Further more, we discuss four related issues:(1) Through reducing the number of operations in history buffer, we can optimize the efficiency for running continuously;(2) Support Undo operation for collaborative document editor through involving a delete counter for each object;(3) Introduce a new timestamp model to support concurrent operations in a single site for shared data;(3) Through involving a NOOP operation and executing transaction operation with all related NOOP operations to guarantee transaction operation is serialized.

进一步，本文讨论了一致性维护的四个相关问题：（1）通过精简操作的历史队列，实现算法持续执行时的效率优化；（2）通过引入对象节点的删除计数器，实现对文档的协同编著中的Undo操作支持；（3）介绍了一个新的支持单站点上共享数据的并发操作的时间戳模型；（4）通过引入空操作NOOP且保持事务操作和相应的NOOP操作同时执行，保证事务操作的序列化。

The mining practice in Tongshan Copper Mine shows that the method of sublevel open stoping with subsequent once-filling and removing with blasting power is more suitable to mine inclined or gently inclined medium-thick deposits with high sulfur. This method can be used to reach the prepurpose including decreasing ore loss and dilution rates, reducing the quantity of mining works and raising the productivity of a stope.

铜山铜矿的开采实践表明，对于倾斜、缓倾斜中厚高硫矿床采矿方法的选择是至关重要的；根据其复杂多变的地质条件及国内外开采状况，提出选用爆力运搬分段空场嗣后一次充填采矿法较为适宜，该法可以达到降低损失贫化率，减少采准工程量，提高采场生产能力的预期目的。

The trial results show that with the disposal of induced caving roof by presplitting blasting and induced caving roof blasting, about 17.8 m in thickness of rock cushion is successfully formed in the inferior abandoned stope, which can bring down the harm of dashing blast of an explosion caused by roof collapse; apparent run-through flaws arise between presplitting blasting holes, and controllable caving is formed in the roof, abrupt collapse of large area roof is prevented, the productional safe surroundings of underground mining is improved; eventually, the resources' reclamation rate is improved from about 70% to 84.6%, and the dilution rate is abated from 25%40% to below 15%, so efficiently withdrawing is actualized.

试验结果表明：采用预裂爆破与诱导崩顶爆破的方法，通过对顶板的诱导崩落处理，成功地在下方采空区形成了厚度为17.8 m左右的岩石缓冲垫层，有效地降低顶板冒落带来的冲击气浪危害；在预裂孔间产生明显的贯通裂隙，从而在顶板上形成诱导可控崩落，防止顶板大面积的突然垮落，改善地下开采安全生产环境；最终资源的回收率由70%左右提高到84.6%，贫化率由25%~40%降低到15%以下，实现了资源的高效回收。

Results:The degenerative changes of articular cartilage in the manipulation group and the sodium hyaluronate group,such as vacuolar degeneration of cytoplasm,decreased quantity and degraded function of orginele,pycnosis of nuclear and necrosis even disintegration of cell,are lesser than that in the group without treatmnet.

结果：手法干预组和透明质酸钠组软骨细胞发生胞浆空泡化，细胞器数量减少，功能减退以及细胞核固缩甚至细胞坏死崩解等退变现象的程度较空白对照组轻，手法组与透明质酸钠组相当。

What are your goals and strategies for growth?

你的成长目标和策略是什么？

And unto the angel of the church in Sardis write; These things saith he that hath the seven irits of God, and the seven star I know thy works, that thou hast a name that thou livest, and art dead.

3：1 你要写信给撒狄教会的使者，说，那有神的七灵和七星的，说，我知道你的行为，按名你是活的，其实是死的。