畸形性的

Objective Neural tube defects are a common congenital malformation in humans, which have affected on the human quality and are the most severe desease of birth defects, which comprises a series of defects such as anencephalia, encephalocoele, myeloschisis and so on because of no and delay closure of the neuropore in the progress of developing embryo.

目的 神经管畸形(neural tube defects，NTD)是人类常见先天畸形，是影响人口素质的最常见、最严重的出生缺陷性疾病之一。

One case with the chief complaint of large head was diagnosed as cerebral gigantism according to the clinical picture and brdin computerized tomography. This case, a one-year-old female infant, experienced rapid growth.

脑性巨大畸形，又名索特斯症条羣，在出生时的表现有特殊的颅面畸形，体重过重，身长过长，头围过大和高骨头成熟度。

Results The number of cases with hemoptysis caused by tracheobronchitis, idiopathic pulmonary hemosiderosis, pulmonary tuberculosis, cardiovascular and pulmonary vascular malformation, and bronchiectasis were 18 (43%), 7(17%), 4(10%), 3(7%), 3(7%), respevtively. Duplication of digestive tract and tumor might cause the symptom of hemoptysis in childhood.

结果 42例咯血患儿中，气管、支气管炎引起的咯血18例(43%)，特发性肺含铁血黄素沉着症7例(17%)，支气管内膜、肺结核4例(10%)，心、肺血管畸形及支气管扩张症分别为3例(各占7%)，消化道重复畸形、肿瘤所致的咯血在儿童也可见到。

The Ilizarov technique was used in 9 patients (11 feet) with the severe rigid talipes equinovarus deformity, in which one patient with syringomyelia, and the orthers with congenital club foot. Prospective goals of correction were made in all the cases.

方法］作者在2000年3月～2005年3月间，使用Ilizarov技术矫正9例11足重度僵硬性马蹄内翻足畸形，将连接于胫骨、跟骨、跖骨的外固定环互相连接、组合成复杂的三维外固定架，通过逐渐调整外固定架矫正畸形，从而使患足达到或接近正常足的外形和功能。

DNAs from a group of sex chromosome abnormal patients〔46 XX male, 45 XO Turner's syndrome, 47 XXY klinelfter syndromes, 46 XX true hermaphrodite, 46 XY hermaphrodite, 47 XYY male, 48 XXXY male〕 was hybridized to ZFT using southern bloting method.

我们对一组性染色体异常的病人(46XX男性，46XX真两性畸形，46XY两性畸形，45XO Turner's综合症，47XXY Klinelfter综合症，47XYY男性，48XXXY男性)DNA，用ZFY探针进行了Southern印迹杂交。

The results showed that all of them could detect the presence of ZFY DNA sequences except a 46 XX"male"and a 46 XX hermaphrodite, our findings confirmed that Ferguson-Smith〔1966〕 forwarded the hypothesis that the X-Y intercharge model for XX maleness can be regarded as an abnormal exchange initaited in a region proximal to TDF and extending to the telomere,and,also strongly suggested that ZFY gene palyed an important role in sex determining of human.

结果除一例46XX两性畸形，一例46XX&男性&外，余均能检测到ZFY DNA序列(ZFY DNA序列存在于46XX真两性畸形和45XO Turner's综合症，在国内外尚未见报道)。证实了1966年，Ferguson-Smith提出的理论：在父源减数分裂期间，X-Y发生不等交换，导致Y染色体DNA插入性易位。XX男性是由于Y染色体上的TDF基因转移至X染色体上所致。

Genetic studies have been performed on the hereditary diseases of disseminated superficial actinic porokeratosis, familial progressive hyperpigmentation and triphalangeal thumb-polysyndactyly syndrome by linkage analysis and sequencing.

本研究通过连锁分析和直接测序的方法，分别对播散性浅表性光化性汗孔角化症、家族性进行性色素过度沉着症和拇指三指节多指并指多掌骨畸形这三种疾病进行了遗传学分析。

Genetic studies have been performed on the hereditary diseases of disseminated superficial actinic porokeratosis, familial progressive hyperpigmentation and triphalangeal thumb-polysyndactyly syndrome by linkage analysis and sequencing.

中文摘要本研究通过连锁分析和直接测序的方法，分别对播散性浅表性光化性汗孔角化症、家族性进行性色素过度沉着症和拇指三指节多指并指多掌骨畸形这三种疾病进行了遗传学分析。

Results At the dosage of 25 mg/kg,AN could induce higher incidence of fetal resorption and death,and decrease the average fetal body weight and le ngth with significant difference(P＜0.05)when compared with neg ative controls.At the dosage of 35 mg/kg,AN could decrease average vital fet us p er litter with significant difference(P＜0.05),and induce chang es of other indexes with highly significant difference(P＜0.0 1).At the dosage of 25 and 35 mg/kg,AN could induce higher teras rate,maternal t eras rate and malformation rate of vital fetus with significant and/or highly s ignificant difference(P＜0.05 or P＜0.01),resp ectively.There existed a dose-effect or dose-response relationship between abo ve indexes and doses.

结果 25 mg·kg-1组死胎率、吸收胎率升高，胎鼠平均体重、体长、尾长减小，与阴性对照组比较差异有显著性(P＜0.05)；35 mg·kg-1组除窝平均活胎数减少，差异有显著性( P＜0.05)，其余各指标与阴性对照组比较差异有非常显著性(P ＜0.01)；25，35 mg·kg-1组畸胎率、母体畸胎率、活胎畸形率升高，与对照组相比差异有显著性和/或非常显著性(P＜0.05或P ＜0.01)，且有明确的剂量效应或剂量反应关系。

Our experiments proved that VEGF have relationship with proliferation and involuting of hemangiomas.

结果显示，增生期血管瘤组织中P53着色的肥大细胞数目为29.64±2.67/HPF，消退期为14.87±4.43/HPF，血管畸形组织中为1.33±0.6/HPF.F检验结果表明：在增生期、消退期血管瘤及血管畸形组织中P53着色的肥大细胞数目有显著性差异（P.05）。

If you are unfortunate enough to the lovelorn, please tell me, I will help you out, really, please contact me!

如果你不幸失恋了，请告诉我，我会帮助你摆脱困境，真的，请联系我啦！

China's plan to cut energy intensity by 20 percent and pollutant discharges by 10 percent between 2006 and 2010 is a case in point.

中国计划在2006年到2010间降低20%的能源强度和减少10%的主要污染物排放，就是一个这样的例子。