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In order to investigate the role of apoptosis and its regulating genes during reperfusion following focal cerebra...

在局性脑缺血研究中,已证实局性脑缺血中心区和半影区的存在。

The morphology and distribution of the eloquent cortex and white matter were evaluated by fMRI before the operation, and the epilepsy focus was localized to guide resections of the tumor and epileptogenic focus by ECoG records during the operation.

术前通过fMRI 了解相应脑功能区皮质和白质纤维束的形态和分布;术中在切除肿瘤前后行ECoG检测,确定致的位置,指导肿瘤及致的切除。

Results Among 96 cases of CD117-positive GISTs, 94 positive for nestin (in amount of this 70 diffusive positive, 21 moderate positive, 3 local positive), the other two were negative. 4 of the 5 CD117-negative GISTs and 26 of 33 Schwannomas expressed nestin too, only 3 of 15 leiomyosarcomas showed focal positive for nestin. All oesophagus leiomyomas and fibromatosis of intestinal demonstrated negativity for nestin.

结果 96例CD117阳性的GISTs中,94例表达nestin,其中70例弥漫强表达,21例中度阳性,3例局阳性,仅2例阴性;5例CD117阴性的GISTs中,4例表达nestin;33例消化道雪旺瘤中26例表达nestin;15例平滑肌肉瘤中3例局表达nestin;10例食管平滑肌瘤、6例肠纤维瘤病均为阴性。

In treatment group, 42 cases received 50 Gy radiation, at 2 Gy per day, 5 d per week in the upper mediastinum, hilus of lung, below the primary focus first and then underwent X-knife for the primary focuses, and other 14 recurrent and metastatic cases received irradiation of 8-12 Gy per day, 5 d by X-knife alone.

治疗组中42例为外照射上纵隔、同侧肺门、隆突下及原发50 Gy/25F后加用X线刀治疗原发5 Gy/次×5次;14例为肺转移癌或手术后外周孤立性复发病行单纯立体定向放射治疗,8~12 Gy/次×5次。

The patients were divided into follow groups (proxima1,middle, dista1 and combination group,or single , multiple, or unilateral, bilateral, or lacune infarct, non lacune infarct ) according to the infarcts locations on MRI.

根据头颅MRI的表现,将患者分为近段组、中段组、远端组、混合组以及单组、多组、单侧病组、双侧病组、腔隙性梗死组与非腔梗组;分析各组的危险因素。

Hours after operation, most nerve cells disappeared and the glial cells were degenerated. There were many mono-nucleus cells infiltrating in transplantation group while a few in control group. One week after operation, tissues in the infarction zone were liquescent with many monocaryons and lymphocytes infiltrating around them in control group.

术后48 h神经细胞大片消失,胶质细胞变性,自体骨髓干细胞移植组有大量单个核细胞浸润,对照组相对较少。1周后对照组梗死区脑组织液化变软,坏死周围可见较多的单核和淋巴细胞浸润;自体骨髓干细胞移植组大鼠部分坏死被新生毛细血管和胶质细胞增生修复,炎性细胞浸润不明显。

Results: The two cases were locally reactive benign lesion and multilocular low-graded malignant lesion.

结果:l例为局性反应性良性病变,l例为多性低度恶性病变。

MRI showed brain atrophy in 11 cases,delayed myelinization in 8 cases,periventricular leukomalacia in 6 cases,abnomal signals of the basal ganglia in 5 cases,brain malaria in 5 cases,cortical infarction in 3 cases and congenital deformation in 4 cases,no abnormal finding in 3 cases.

其中脑萎缩11例,脑白质髓鞘发育延迟8例,脑室周围白质软化6例,基底节异常信号5例,脑软化5例,皮层梗死病3例,先天畸形4例。3例患者MRI检未见明确异常。

The number of DC is more in the cases of those that have more necrotic areas and lymphocytes infiltration.

树突状细胞形态不规则,绝大部分DC分布于坏死和汇管区间质中与淋巴细胞伴行,肝细胞内一般不常见,坏死越多,淋巴细胞浸润越多的病例中DC细胞也越多。

Electron microscopic examination showed that the spinal cords were normal in group N and A, slight edema of mitochondria and endoplasmic reticulum in group B, loosened fibrous layers in medullary sheath, edema and local degeneration of neuraxis in group C,and shrinkage of nuclear membrane, serious edema of ER, vacuolus change of mitochondria and local demyelination in group D.

电镜结果显示,N组和A组脊髓超微结构正常;B组线粒体、内质网轻度水肿;C组脊髓髓鞘纤维板层结构疏松,轴索肿胀,局变性;D组脊髓神经元细胞核膜皱缩,线粒体空泡样变,内质网肿胀严重,局性脱髓鞘改变。

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