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Results The rates of ECG abnormalities in group of OCSP were 95.45% for TACI、80.35% for PACI、62.50% for POCI and 48.54% for LACI. The rates of ECG abnormalities in group of Adams were 83.72% for large infarction, 60.42% for small infarction,53.2% for lacunar infarction and 20% for no infarction.

结果 在OCSP分型中,TACI、PACI、POCI和LACI的心电图异常率分别是:95.45%、80.35%、62.50%和48.54%;在Adams分型中大死组、小死组、腔组和阴性组的心电图异常率分别是:83.72%、60.42%、53.23%和20%。

The relationship between each of four subtypes and ECG abnormalities was evaluated.Results The rates of ECG abnormalities in group of OCSP were 95.45% for TACI、80.35% for PACI、62.50% for POCI and 48.54% for LACI. The rates of ECG abnormalities in group of Adams were 83.72% for large infarction, 60.42% for small infarction,53.2% for lacunar infarction and 20% for no infarction.

结果 在OCSP分型中,TACI、PACI、POCI和LACI的心电图异常率分别是:95.45%、80.35%、62.50%和48.54%;在Adams分型中大死组、小死组、腔组和阴性组的心电图异常率分别是:83.72%、60.42%、53.23%和20%。

Results (1)The permillage of myocyte apoptosis in infarct area in elder patients with sudden death caused by AMI was significantly higher than that in control group(663.00‰±117.12‰ vs 34.30‰±20.68‰,P<0 .01).However the permillage of myocyte apoptosis in 1-vessel,2-vessel,and 3 - vessel disease were 514.28±165.12‰,564.38‰±102.33‰ and 668.25‰±127. 19‰,respectiverly,significantly higher as compared to control group(All P< 0.01).But no significance was found among the three groups.(2)The size of DNA f ragment about 180~200 bp was found only in those patients with two and three ve ssels involoved.(3)The electron microscope showed the characteristics of myocyte apoptosis episodes,the others showed the characteristics of necrosis.

结果 TUNEL法发现,猝死者死区的心肌细胞凋亡千分数老年组(663.00‰±117.12‰)明显高于正常对照(34.30‰±20.68‰)(P<0.001);心肌细胞凋亡千分数在冠脉1支病变者(514.28‰±165.12‰)<2支病变者(564.38‰±102.12‰)<3支病变者(668.25‰±127.19‰),虽然均明显高于正常对照(均P<0.01),但三组之间比较则无统计学上的差别(均P>0.05);冠脉2~3支病变者死区的心肌细胞DNA电泳可见相差约180~220 bp的阶梯片段;电镜发现猝死者死区内的心肌细胞核膜完整、染色质浓集、电子密度增加的凋亡特征,有的则出现核膜破裂、染色质溶解成碎屑的坏死现象。

Five rats in both groups were executed at 3, 7, 14, and 28 days after model establishment. RNA was extracted from the same site of left anterior wall, and the polymerase chain reaction was used to semiquantitatively analyze the Ang1 and Tie2 receptor mRNA expression with GAPDH gene as internal control; meanwhile, the immunohistochemistry was used to detect vascular density in and around infarction area.

于术后3,7,14,28 d 四个时间点,每组取5只处死,取心脏左室前壁同一部位,提取总RNA,用RT-PCR的方法,以GAPDH基因为内参,进行半定量分析检测正常心脏及死后血管生成素1及Tie2 mRNA的表达;同时用免疫组化的方法检测各时间点死区域以及死周边区域血管数量。

Results: At each examination tine, rADC in infarct core was lower than normal. Within 3 days after MCAO/R, rADC in infarct margin was lower than normal, and 7 days later, rADC equaled approximatively with normal.,and even was higher than normal.

但是,无论是在死灶中心还是边缘,TMS组的rADC值均比相应时间点的假刺激组rADC值高;两组内,死边缘的rADC值均比死中心的rADC值高。

Diabetes mellitus have a lesser ability to develop collateral vessels after acute myocardial infarction. It mainly affects the process of arteriogenesis, but not angiogenesis. This effect may be partly due to the lower expression of bFGF.

糖尿病主要是通过影响动脉生成阻碍心肌死后冠状动脉侧支循环的形成,死区和死周边区的血管内皮细胞、心肌细胞bFGF表达减少参与了该过程。

Callosal atrophy,lateral ventricle enlargement and extensive WML are important predictors of incidence of dementia in the small vessel disease;however,left cortical infarct,especially left parietal infarct,is important predictor of incidence of dementia in the multi-infarct.

小血管病患者有胼胝体萎缩,侧脑室扩张和广泛大脑白质病变提示VaD;而左侧大脑皮层死,尤其左顶叶死是提示多发脑死患者为VaD的指标。

The indexes that could significantly discriminate the two groups was: callosal atrophy,ventricle-to-brain ratio,WML area,left cortical infarct area,left parietal infarct area,total cortical infarct area.

有效判别指标依次为:胼胝体面积比率、脑室-脑比率、大脑白质病变面积、左侧皮层死面积、左顶叶死面积和皮层死总面积。

Stenosis of internal caroid antery was found in 32 of 48 branches in 24 case. 5 branches were occlusive and 11 branches were normal. 22 cases with large or moderate cerebral infarction volume (>5 cm3) confirmed by CT and MRI were smaller than those on MSCTPI as having abnormal perfusion lesions,which were moderate and obvious stenosis and occlusion on MSCTA. In 2 cases with small cerebral infarction volume(<5 cm3), MSCTPI and MSCTA revealed normal.

其中32支颈内动脉呈不同程度的狭窄,5支颈内动脉闭塞,11支血管无狭窄。22例在常规CT及MRI图像上为中及大体积死(>5 cm3)的患者,MSCTPI发现与死灶相对应的异常灌注区,且均比常规CT及MRI图像上病灶体积大, MSCTA显示颈内动脉呈中重度狭窄或闭塞。2例未发现明显灌注异常的患者,为小体积死灶(<5 cm3),MSCTA显示颈内动脉正常。

Stenosis of internal caroid antery was found in 32 of 48 branches in 24 case. 5 branches were occlusive and 11 branches were normal. 22 cases with large or moderate cerebral infarction volume (>5 cm3) confirmed by CT and MRI were smaller than those on MSCTPI as having abnormal perfusion lesions,which were moderate and obvious stenosis and occlusion on MSCTA.

其中32支颈内动脉呈不同程度的狭窄,5支颈内动脉闭塞,11支血管无狭窄。22例在常规CT及MRI图像上为中及大体积死(>5 cm3)的患者,MSCTPI发现与死灶相对应的异常灌注区,且均比常规CT及MRI图像上病灶体积大, MSCTA显示颈内动脉呈中重度狭窄或闭塞。2例未发现明显灌注异常的患者,为小体积死灶(<5 cm3),MSCTA显示颈内动脉正常。

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