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心脏舒张期

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Methods:Paticipants consisted of 32 simple VSD patients and 27 simple PDA patients excluded of any other diseases by physical examintation and electrocardiogram and x-ray. Patients were suggested echocardiography before and one week after the surgerys. Parameters such as Left ventricular ejection fraction、Fractional shortening、Left ventricular end-diastolic dimension、Left ventricular end-systolic dimension、Heart rate and Aortal velocity peak were measured.further more ,the Tei index which is originated from Pulse-wave Doppler and Tissue-Doppler Imaging were also calculated under ECG monitoring.

研究对象与方法:研究对象分别为排除其它心脏疾患的单纯动脉导管未闭患儿及单纯室间隔缺损患儿,手术治疗前后于心电监护下先行常规超声检查,获取心率、R-R间期、左室射血分数、主动脉峰值流速、左室收缩末期内径及左室舒张末期内径等值,并分别利用频谱多谱勒及组织多谱勒法测取患儿左室Tei指数(即PW-Tei及TDI-Tei),多次测量并取其均值。

Cases with renal transplantation were performed with dynamic state CDFIin Ultrasound Dept. of Nan fang Hospital from April, 2005 to October, 2006. Theexamine time is respectively after operation in three days, seven days, one month andthree months. Before operation examine the condition of uropoiesis function such as apair of kidney, ureter, bladder and cardiac function. After operation reexamine thecondition of cardiac function once again, and examine TK detailed and completely:First, using two-dimensional imaging to observe the shape and the volume of the TK.Secondly, using Color Doppler to observe the renal artery and each artery inside theTK. Finally, using pulsed Doppler to measure the peak systolic velocity, enddiastolic velocity and resistance index.

对南方医科大学南方医院超声诊断科自2005年4月~2006年10月对152例同种异体肾移植患者进行动态CDFI监测,超声检查时间分别为术前与术后3d、术后7d、1个月及术后3个月,术前超声检查双肾、输尿管、膀胱等泌尿系功能情况及心脏功能情况,肾移植术后再次对心脏功能情况进行跟踪复查,并对移植肾进行详尽检查:先用二维超声观察移植肾的形态、大小,随后应用CDFI观察移植肾动脉及肾内各级动脉的血流充盈情况,最后用脉冲式多普勒测量收缩期峰值流速、舒张末期流速、阻力指数。

L-arginine, an NO precursor, reduced the contractile amplitude and end-diastolic cell length in the cardiomyocyte; but reversibly increased LVDP,±dp/dtmax, and coronary flow in isolated perfused rat heart.

2NO的前体L-精氨酸(L-arginine, L-Arg)引起心肌细胞舒张期细胞长度缩短、收缩幅度降低。离体灌流心脏LVDP、冠脉流量、和±dp/dtmax增高,用K-H液复灌后可恢复正常。

Arginine, a NO precursor, reduced the contractile amplitude and end diastolic cell length in the cardiomyocyte, but reversibly increased LVDP,眃P/dtmax and coronary flow in isolated perfused rat heart.

-Arp预处理,再行Fe-HQ(5卜mol/L)灌流,与单纯的LAfg或Fe-HQ组相比,心肌细胞舒张期细胞长度、收缩幅度和速度减小;离体灌流心脏LVDP、tdP/im.x、心率和冠脉流量明显下降,冠脉流出液中LDH、CK增加。

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