均一的

The growth inhibiting rate of T24 cell lines were detected by MTT methods, apoptosis of cells were detected by flow cytometry, the mechanism of apoptosis was analyzed by detecting the protein expression of Bcl-2, Bax, Caspase-9, Caspase-3 and cytoplastic protein Cytochrome C. 4 We injected live T24 cells into the subcutaneous space of nude mice and successfully built up the animal model of bladder carcinoma. The effect of CS-PAA-EPI polymer magnetic microspheres targeting chemotherapy was investigated by HE staining, TUNEL ,tumor weight and volume inhibition rate. Results: 1 TEM revealed that the CS-PAA polymer magnetic microspheres were regular spherical shape,the average diameter was 80nm in dry condition. By controlling the pH value of the medium,polymers had positive or negative zeta potential. VSM showed the CS-PAA polymer magnetic microspheres had superparamagnetic. The diameter of CS-PAA-EPI polymer magnetic microspheres were 200nm in solution by DLS examining,the embedding ratio was 20%,the EPI loading rate was 15%, which was higer than reported in other articles. 2 Raw eye observation found that the rat"s bladder of treatment group was brown color,which meaned the aggregation of iron particles, compared with the control group, iron stain found iron particles were assembled in rat"s bladder of the treatment group, the amount of iron particles in liver and spleen were less obviously.

研究结果：1合成的CS-PAA磁性聚合物微球呈球形，大小均一，TEM测定其干态下粒径为80nm左右，磁化曲线证实具有超顺磁性，具有一定的PH敏感性，固载表柔比星后，水溶液性状稳定，无沉淀物，DLS测定直径约200nm左右，测定载药率为15％，较文献报道高，包封率为20％。2肉眼观察试验组大鼠膀胱表面呈褐色，可见大量的Fe粒子聚集，普鲁士兰染色法显示，试验组大鼠膀胱壁内有大量的Fe粒子，分布至膀胱壁全层，与对照组大鼠相比，试验组大鼠的肝、脾内的Fe粒子聚集量明显降低；HPLC测定结果与Fe染色相同；高剂量磁性CS-PAA-EPI生理盐水组及单纯EPI生理盐水组均在给药后14天出现血肌酐和尿素氮的升高，其他组大鼠血生化指标没有明显变化。3MTT法发现，高、中、低剂量磁性CS-PAA-EPI生理盐水组在外加磁场的协同作用下杀伤T24细胞效应明显高于单纯的EPI生理盐水组，FCM发现试验药物组可引起明显的肿瘤细胞凋亡，试验药物治疗组细胞胞浆内出现了由线粒体释放出的细胞色素C，试验组细胞Bcl-2蛋白减少，Bax蛋白变化不明显，Caspase-3、Caspase-9蛋白受到了激活活化。4高、中、低剂量磁性CS-PAA-EPI生理盐水组的瘤重抑制率和瘤体积抑制率均明显高于单纯的EPI生理盐水组(P＜0.01)，其中高剂量组的抑制率最高。

In the course of the impulse through underground mediator, because the physical property and the geometric property of mediator is non-uniform, wave form and wave amplitude will change very much and the impulse after shock、antenna direction figure、the couple degree of ground surface、system interfere、non-uniform of the underground mediator、reflection surface's rough cause the disturb of radiation scatter and diffract will complex the figure .

脉冲在通过地下介质的过程中，由于介质的物性和几何性质的不均一性，波形和波幅将发生较大的变化，而脉冲余振、天线方向图形、天线的地表偶合程度、系统内部的干扰、地下介质的不均匀、反射面不光滑等引起的辐射效率、散射的变化以及剖面旁侧的绕射等干扰，均使实时记录图像复杂化。

At the BCL of 500ms, 1000ms and 2000ms,the VWtimes increased markedly with the BCL prolonging, and the degree of increasing was even obviously when heart rate was slow (BCL=2000ms or 1000ms). The enlargement of VWs was a most important reason to increase the incidence of ventricular arrhythmias; 2）At the BCL of 500ms, 1000ms or 2000ms,the VWtimes of the premature stimulates S2 was at endomembrane were wider than at the outermembrane. We supposed that premature stimulates come from endomembrane was easier inducing VF compared with outermembrane;3The VWtime of unidirectional block was wider than reentry's, we can see that reporlarization dispersion changed dynamicly. 4The QRS polar of the premature stimulates was opposite the primary beats ,which suggesting that excitation of inducing premature beats was coming from epicardial. That is to say electrotonic potential take part in the creation of reentry;5With the ratio of the Tp-e/QT increasing the occurrence of VF was upgrading. So the ratio was an effective method to estimate the event of SCD.6 The VWtimes of S3 were broaden than S2's. But we can not study penetratingly, which is the contents of our future studies.

在BCL为500ms、 1000ms和2000ms刺激条件下，随着刺激周长的增加单向传导阻滞时间易损窗呈增大趋势；并且在心率较慢时(BCL为2000ms和1000ms)增大最明显，是LQTS患者室性心律失常发生率增加的原因之一；2）在BCL为500ms、 1000ms和2000ms刺激条件下，S2位于内膜侧时时间易损窗大于在外膜侧时的，推测来自于内膜侧的期前刺激易于诱发室性心律失常；3）折返激动时间易损窗小于在单向传导阻滞时间易损窗，折返易发生于S2刚进入单向传导阻滞区间时，这说明复极梯度的不均一是动态变化的；4心电图上倒置QRS波与正常S1刺激所引起QRS波极性相反，提示不同位置S2刺激引发的室性早搏的兴奋均来自于外膜侧，说明了电紧张电位扩布参与了折返的产生；5）Tp－e/QT可以反应跨膜复极离散度，随着Tp－e/QT比值的增加PVT的发生增多，其可以用来预测室性心律失常的发生。6）随着期前刺激数目的增加时间易损窗增大。

The feldspars of topaz-lepidolite granite in Yashan late stage are P-rich albite and Kfeldspar, and the phosphorus goes into feldspar structure in the form of PAlSi〓 substitution. The phosphorus contents of feldspars vary according to their crystal habitus. In general, the feldspars of later generation have the higher average phosphorus content than that of earlier generation, and the albite contains higher phosphorus than the K-feldspar in the same generation. The zircon is highly rich in Hf, U, P and Al. The phosphorus enters the zircon structure mainly by the form of〓P〓〓Si〓, Al〓P〓Si〓 or P〓Al〓Si〓, Zr〓 substitution. The P-rich zircon is the production of the highly evolved magma, and it might be one of the important characteristic minerals of the high-P subtype granite. The manganocolumbite, manganotantalite, wodginite and titanowodginite are the main niobium and tantalum minerals.

雅山晚阶段黄玉锂云母花岗岩的长石矿物是富磷长石，磷以PAlSi〓替换方式进入长石结构中，并且在长石中的分布很不均一，一般是晚结晶的长石比早结晶的长石的磷含量高，同期结晶的钠长石比钾长石的磷含量高；锆石矿物为高度富铪、铀、磷和铝的锆石，磷主要以(Y， HREE， Fe)〓P〓〓〓Si〓〓、Al〓P〓Si〓〓、P〓Al〓Si〓〓Zr〓〓等替换方式进入锆石晶格中，富磷锆石是岩浆高度演化的结果，是高磷花岗岩的特征矿物之一；雅山含有丰富的磷锂铝石，是高磷花岗岩的主要磷酸盐矿物；铌—钽矿物主要有铌锰矿—钽锰矿、锡锰钽矿—钛锰钽矿、细晶石等。

Three important conclusions are as follows:(1) the H2O content in garnet and omphacite can be up to 2000ppm and 3000ppm by weight respectively, indicating that they are significant carrier recycing surficial water into deep earth;(2) the heterogeneous distribution at the small scale of the H2O content and hydrogen isotopic ratios suggest that the whole subduction- exhumation process should be very fast;(3) the regular decrease of H2O content from rim to core within some garnet and omphacite grains indicates that hydrogen diffused out from mineral lattice during exhumation in response to sharp pressure decrease, and such hydrogen is expected to be involved in the early-stage retrograde metamorphism.

取得的主要科学认识包括：(1)石榴石和绿辉石的结构水含量可以分别高至2000ppm和3000ppm，这表明它们是板块俯冲过程中将地表水携带进地球深部的重要载体；(2)水含量和氢同位素组成表现出小尺度的不均一分布，说明板块的俯冲和折返过程是十分快速的；(3)在板块折返的早期，由于压力的降低，矿物中的H 会发生不同程度和尺度的扩散，这是早期退变质流体的重要来源。

Based on a computing model of floor heating residences, indoor thermal environment and heat distribution under the effect of heat charge/discharge, operation control and solar radiation has been concluded. Concept and formula of equivalent heat supply has been put forward which indicate that actual heat supply will be equal to the sum of design heat supply and equivalent heat supply. Recommend coefficient has been given taken Dalian as an example. Computed according to the new method, design heat supply can be reduced to 37% in cloudy day and 43.3% in sunny day, energy saving effect is very obvious. In Tromb wall solar house, effect of concrete wall on indoor temperature swing and attenuation of temperature wave is very obvious. While the outdoor air-temperature swing exceeds 10℃, indoor air-temperature swing belows 3℃. In the experiment, maximal difference in temperature between inner surface and outer surface of the 300mm wall exceeded 10℃. Heat storage and collector efficiency varies adversely according to solar radiation. Factors such as thickness, material, absorptance of the wall and permeation of the glass cover all have big influence on heat storage and collector efficiency. There exsisted an optimal thickness of the wall, which can make the best of heat storage and collector efficiency. Most of the heat stored in conventional Trombe wall during the daytime has been lost to the outside at night without heat preservation. Heat preservation on the outside surface of the wall has effectively improved heat release performance of the wall at night, heat supply to the room has increased too.

通过建立的地板采暖系统动态热性能分析模型，得出了在蓄放热特性、运行方式和太阳辐射等因素耦合作用下的室内热环境及热量分配比例，提出了等效供热量的概念及计算公式，指出实际所需供热量应等于设计供热量加上等效供热量，并以大连为例，给出了等效供热量的修正系数，以新方法计算，阴天可减少设计供热量37％，晴天最大可以减少设计供热量43.3％，节能效果显著；集热蓄热墙式太阳房中，混凝土蓄热墙的室温均一化效果和对温度波的削减作用非常明显，当室外温度波动最大幅度超过10℃时，室温波幅不超过3℃，实验中300mm厚墙体内外表面温差超过10℃；墙体蓄热效率与集热效率随太阳辐射照度的变化呈相反的变化趋势；墙体厚度、材料、表面吸收率以及盖板透过率等因素对集热和蓄热效率均有较大的影响，存在一个最佳的墙体厚度值，使得墙体集热和蓄热综合性能最优；传统的蓄热墙夜间没有外保温，辐射散热损失很大，研究表明墙体外保温方式明显改善了蓄热墙夜间的散热性能，增加了向室内的供热量。

Analyzing the model, especially the activity of Taihang Mountain piedmont fault, we got such main conclusion:1. Based on sequence stratigraphy, the strata is divided from the selected drills. And the Quaternary stratigraphic framework of Handan city is established, dividing the Quaternary strata into four parts- Qh, Qp3O , Qp2Y and Qp1G.2. With all the selected drill data of Handan city, a drill database is established. A quaternary strata 3D model of Handan city is imitated by GOCAD and ArcGIS, and so are the bottom structural map of each horizon.3. Analyzing the 3D model and the contradistinction section of drills, we got: the stratum of Qh and Qp3 is smooth and flat, with a feature of a higher west, little difference between south and north and undistinctness of faults; there are several depocenters along S-N and N-W in the stratum of Qp2, and the evolution of the stratum is controlled by a couple of ruptures, which means the tectonic movement is active in this period of time.4. Since quaternary, main tectonic movements happened in Qp2 and have been stable in Qp3 and Qh.

获得主要结论如下：1、利用层序地层学的方法将收集的邯郸市钻孔以及论文所依托项目野外施工的钻孔进行了具体的地层划分与对比，建立了邯郸市第四系等时地层格架，将邯郸市第四系划分为全新统、更新统上部欧庄组(Qp3O)、更新统中部杨柳青组(Qp2Y)和更新统下部固安组(Qp1G)。2、利用收集到的邯郸市水文、工勘钻孔以及所依托项目初勘和详勘两个阶段野外施工的钻孔数据，建立钻孔数据库，通过使用三维建模软件GOCAD和地理信息系统软件ArcGIS等进行模拟，得到邯郸市市区部分第四系地层三维可视化模型，并获得各个地层的底部构造图；3、通过对所天生模型和钻孔廊带对比剖面的分析，可以得到：全新世和更新世晚期(Qp3)时期地形整体较平缓，整体上显示西高东低、南北差异不大的格式，断裂显示不明显；更新世中期(Qp2)时期沿南北向和北西向存在几个沉积中心，地层发育受几条断裂的控制，反映了研究区的构造活动在更新世中期较为活跃；4、邯郸市自第四系以来，主要构造运动均发生于更新世中期，到更新世晚期及全新世时期逐渐趋于稳定，进而使更新统上部和全新统地层沉积均一且完好。

For Southwestern Margin of Aqikekule Lake ophiolite, their field geological, petrological, minerological, petrochemical and geochemical characteristics show that:① it outcropped as tectonic slices along the near west-to-east strike Kunzhong fault and is composed of metamorphic perodotties, cumulates and volcanic rocks, in which, chromites are distributed in the upper part of metamorphic peridotites as pods, or in the lower part of cumulates as near-strata;② metamorphic peridotites include serpentinites, chromite-bearing serpentinites, chlorite-epidote schists and chromitites, of which, chromitites have nodular and orbicular structure, and cumulates include pyroxenits, serpentinites, chromite-bearing serpentinites, chromites and metamorphically mafic rocks and only basalts are seen in volcanic rocks;③ Cr# of chromites suggest that they formed in the SSZ and Al〓O〓 and TiO〓 of metamorphic peridotites also suggest SSZ environment;④ metamorphic peridotites have V type and enriched LREE patterns, cumulates have from strongly depleted LREE, flat REE to enriched LREE patterns with universally striking positive Eu anomalies and basalts show flat REE or slight enriched LREE patterns with no Eu anomalies;⑤ trace element and Sm-Nd isotope characteristics of metamorphic peridotites imply their strikingly heterogeneous mantle character ε〓(t+4.39～+26.20 and later Nb, Ta fertilization;⑥ trace element characteristics of basalts and their tectonic diagrams show they probably formed in the rifted island arc or back-arc basin environment.

对阿其克库勒湖西南缘蛇绿岩，野外地质、岩石学、矿物学、岩石化学以及地球化学等特征表明：①该蛇绿岩以近东西向、沿昆中断裂呈构造岩片出露，由变质橄榄岩、堆晶岩和火山岩三个单元组成，其中见铬铁岩呈豆荚状产于变质橄榄岩的上部，或呈似层状产于堆晶岩的下部；②变质橄榄岩包括蛇纹岩、含铬铁矿蛇纹岩、绿帘绿泥片岩和铬铁岩等类型，其中，豆荚状铬铁矿具有结核状构造和球状构造，堆晶岩包括辉石岩、蛇纹岩、含铬铁矿蛇纹岩、铬铁岩和变质基性岩等类型，火山岩仅见玄武岩；③铬铁矿的Cr#表明其形成在俯冲带，变质橄榄岩的Al〓O〓和TiO〓成分也指示了SSZ环境；④变质橄榄岩的稀土配分型式见V型和LREE富集型两种型式，堆晶岩表现出从LREE强烈亏损、REE平坦分布到LREE富集的配分特征，并且普遍具有醒目的正Eu异常，玄武岩的稀土配分型式表现为平坦型或LREE略富集，无Eu异常；⑤变质橄榄岩的微量元素及Sm-Nd同位素特征指示了其地幔的显著不均一性ε〓(t为+4.39～+26.20以及Nb、Ta在后期的富集；⑥玄武岩的微量元素特征及构造图解表明其可能形成在裂谷岛弧或不成熟的弧后盆地环境。

In respect that various requirements of load and temperature on different parts of the baker, firebrick lining was chose reasonably, and the dosage of light heat preservation brick is in enlargement. As a result of that, the weight of the furnace was decreased, and increased its performance of heat preservation and cumulation was increased consumedly. With the use of ""W"" type fire tunnel and straight-through dilatation joint, and two enlargement of the perpends on the wall appropriately, all the problems of heat preservation in the anode baker, uniform temperature in the tunnel, and its life span were solved effectively. In the research of anode blocks in and out of the furnace, and of tidying it up, the multi-function crane clamps was alented and the assembling unit was reconstructed, which made it easy to automatic ally assemble the carbon blocks of various specifications with only one set of assembling unit.In the aspects of automation, a new type pulse combustor and solid thermocouple, as a result of that, not only the control accuracy of the fire tunnel's temperature was increased, but also the system function was improned to be more dependable, safe and practicable.

在焙烧炉炉体研究方面，针对焙烧炉不同部位的负荷及温度要求的不同，合理选用耐火材料，加大轻质保温砖的用量，既减轻炉体的重量，又大大提高炉体的保温蓄热性能；火道墙采用&W&型火道结构，直通性膨胀缝，并适当加大火道墙竖缝，有效地解决了阳极焙烧炉的保温、火道温度均一及火道墙的使用寿命等问题；在阳极炭块装出炉及清理等研究方面，通过对编解机组及多功能天车夹具进行改造，实现一套机组对多规格炭块的自动编组、解组及装出炉问题；焙烧炉自动化控制研发中，采用先进的分散式控制系统，研制开发新型脉冲燃烧器及实体型热电偶，不仅提高了火道温度的控制精度，而且提高了系统的可靠性、安全性、实用性。

The following main results are obtained: The TiO_2 photocatalyst with small crystallite size, high surface area, narrow and uniform pore size distribution, and microporous frameworks could be prepared out by applying MW radiation in the preparation process. The microwave-induced fluorescence technique verified for the first time that microwave enhanced the formation rate of hydroxyl radical, leading to the increase in the photocatalytic efficiency. Compared with the conventional catalyst, TiO_2 prepared by MW dielectric heating owns a higher UV absorption ability, and its optical absorption edge and photovoltaic response are shifted toward the short wavelength region, resulting in increase of photooxidation efficiency. The photocatalytic conversion and the mineralization ratio of acetaldehyde are increased respectively by 30% and 40% over the TiO2 prepared by MW radiation when compared to the TiO2 prepared by the conventional heating. For the MW-assisted photocatalytic reaction over the MW-prepared TiO2, production of hydroxyl radicals is enhanced by 22.5%, and the photocatalytic conversion is accordingly increased by 20%. Similarlly, applying MW also increased the photocatalytic conversion and the mineralization ratio of acetaldehyde over TiO2/Al2O3 sample.

论文得到如下主要结果和结论：(1)微波介电加热TiO_2 溶胶可得到晶粒度小、光催化活性高、比表面积大和孔径分布窄而均一，且微孔发达的TiO_2光催化剂；在溶胶干燥处理过程中微波可使催化剂表面缺陷增加，进而导致光催化反应过程有更多的活性羟基自由基产生；(2)微波制备能显著增强TiO_2 样品的紫外光吸收率，并使其光吸收和光伏响应阈值发生蓝移，从而提高TiO_2的氧化还原能力；(3)与常规加热法所制TiO_2比较，微波法制备的TiO_2对乙醛的光催化降解转化率提高30%，CO_2生成率提高40%以上；(4)与未加微波辐射时相比，发现在光催化反应过程中施加微波，TiO_2 的羟基自由基生成速率提高了22.5%，相应CH_3CHO 光催化降解转化率提高了20%；对Al_2O_3/TiO_2催化剂，CH_3CHO 光催化降解转化率甚至提高了33%，同时CO_2 的生成率也都大幅度提高；(5)微波辐射可改变光催化降解乙醛的产物分布，推断施加微波时乙醛光催化降解按照羟基自由基引发的链式反应机理进行，微波&非热效应&起主要作用。

Methods: Five patients with parkinsonism or dystonia were assigned to general anesthesia using an modified endotracheal tube.

本实验依照人体实验之相关规定进行，五位患有帕金森氏症或肌张力异常的病人接受神经立体定位手术。

If you can benefit from this book, it is our honour.

如果您能从本书获益，这将是我们的荣幸。