可转移性

This kind of technique is a kind of micro-hurt spinal surgery technique and can be used in osteoporotic compressed vertebral fracture, vertebral body angioma and transfer tumors.

经皮椎体成形术是一种的微创脊柱外科技术，可用于治疗骨质疏松性椎体压缩骨折，椎体血管瘤和椎体转移瘤。

Invasion by malignant cells can cause either regional lymphadenopathy, as in patients with head and neck tumors, or generalized lymphadenopathy, as in patients with disseminated carcinomatosis.

恶性细胞侵犯可导致局部淋巴结病如在头颈部肿瘤的病人中，也可是全身性淋巴结病如在播散性癌转移的病人中。

BackgroundBreast cancer bone metastasis which occupy 70% of the distant metastasis is one of the most common clinical disease. It can cause hypercalcemia, focal baryodynia, pathologic fracture and so on.

乳腺癌骨转移占乳腺癌远处转移的70%，是临床上一种常见的严重疾病，可引起高血钙症、局灶性剧痛及病理性骨折。

In search of databases, the deduced products of sanP, sanQ, sanR, sanS, sanT and sanU show highest similarity to those of nikP2, nikQ, nikR, nikS, nikT and nikU of S. tendae respectively. In comparison with the proteins of identified function, it is indicated that sanP encodes a thioesterase, sanQ encodes a cytochrome P450, sanR encodes a uracil phosphoribosyltransferase, sanS encodes a carboxylase, sanT encodes a histidinol-phosphate aminotransferase and sanU encodes a mutase.

在蛋白数据库中比较结果表明，sanP、sanQ、sanR、sanS、sanT和sanU基因编码的蛋白分别和唐德链霉菌的尼可霉素生物合成基因nikP2、nikQ、nikR、nikS、nikT、nikU六个基因编码的蛋白同源性最高；根据和已知功能蛋白的比较，推测sanP基因编码的是硫酯酶，sanQ基因编码的是细胞色素P450，sanR基因编码的是尿嘧啶磷酸核糖转移酶，sanS基因编码的是羧化酶，sanT基因编码的是组氨醇磷酸氨基转移酶，sanU基因编码的是一种变位酶。

By using complementary variable method to analyze the state-changing equations of this queueing system, the generating function of stationary probablity distribution of retrial queue length, some performance indexes such as three different stationary state probablity,stationary availability, and stationary failure frequence of the transfer-unit are derived.

研究通信网络中交换单元的可修模型M1，2，3/G/1，呼叫的到达是重试性的，利用补充变量法对排队系统的状态转移方程作了分析，求得了重试队列稳态队长概率分布的母函数以及交换单元的处于三种不同状态下的稳态概率、稳态可用度及稳态故障频度等性能指标。

Studies also indicated that genistein exsists not only in soybeans but also in many kinds of plants such as vegetables and fruits.As a potential anticancer agent, the actional mechanisms of genistein mainly includes as follows:First, genistein can depress the activity of protein tyrosine kinase and transduction pathways for the phosphorylation of receptors and mitosis signal. So genistein can lead to cells' proliferation depressed. Second, genistein has minimal effects of phytoestrogens. It can be combined with estrogen receptor and improve the synthesis of cellular sex hormone binding glulobin, and improve the activity of UDP-glucuronyl transferase. Through these pathways, it can inhibit the cell activity of breast cancer and prostate cancer.

作为一个很有潜力的抗肿瘤物质，三羟异黄酮的作用机制主要包括：①抑制蛋白酪氨酸激酶活性，可阻抑PTK引起的受体磷酸化和有丝分裂的信号传递，导致癌细胞增殖受抑；②弱雌激素作用：可通过与体内雌激素受体结合，并可增加细胞内性激素结合球蛋白的合成，增加UDP-葡糖醛酸转移酶的活性等途径抑制乳腺癌和前列腺癌细胞活性；③拓扑酶Ⅰ和Ⅱ抑制剂，抑制细胞活性；④上调细胞周期性负性调节因子P21WAF1/CIP1的表达，使之负性调节因子作用增强；⑤可阻止胰岛素样生长因子-Ⅰ、肝细胞生长因子和神经生长因子的作用而抑制肿瘤生长；⑥其他：抗氧化作用、抑制热休克蛋白、诱导细胞凋亡、抑制新生血管生成和抑制多种耐药相关蛋白等。

RSP-810A is single component liquid photoimageable plating-resist allochromatic ink , which is screen printing or roller coating type , it can provide such performance as high resolution , excellent adhesion , so it's fit to professionally make precise inner layer of printed circuit boards and flexible circuit boards , also it's available to production quantity requirement for acid or alkali etching and photograph transfer.

RSP-810A系列为网印或辊涂两用型液态感光线路变色油墨，具有高解象度及良好的密著性，适用于印刷电路板精密内层专业制作及挠性板线路制作，可符合酸碱性蚀刻及细线路板影像转移的量产要求。本系列产品具有以下优点

TyPe II collagen induced arthritisln the rat ank1e joint andoVathumin as antigen induced arthritis WA in the rabbit knee joint wereestab1ish2 Qualitative evaluation of me in skin, muscle, synovium, cedilagearound joint and blood was performed by OMA3 The CIA rats were treated on day 7 after hind paw swelling and erythemaAnimals were injected intravenously with ase at a dose of 10mg/kg,tWenty minuots 1ater, one ankle of the rats random1y assigned was exPosedlaser irradiation at l00J/cm fOr l000 seconds, and another ankle wasM grouP wihout laser The other two groups is unmanipulatedcontrol group and untreated CIA group Bimaleolar ankle widthmeasuremellts were taken in all animals every tWo days using amicrometer The histopathology of the ank1e Joint was assessed at day 21after disease onset4 The pro1iferating cell nuclear antigen WCNA of CIA treated by PDT andthe HMME group without laser was doterdrined by immunohistochemiStry5 The AfA rabbits were treated on day 7 after knee swelling and erythemaThe theraPy invo1ved lntravenous injection of l0mg/kg HMME, fOl1owedby 20 minues period in dim light, and transdermal light treatment with\l00 J/cm2 fOr l000 seconds The inner sides of the treated Anees wereirradiated at first, and then the outer side did 24 hours later, the synovialtissue of the Anees joint were removed and in situ cel1 aPoptosis wasdetCCted With tednal deoxync1eotidyl transferase-mediated dUTP nickend labelingR6suIt8:l The pathologic changes of CIA and AIA include subsynovial inflammation,opovial hyPerplasia, pannus formation, cartilage and bone destructionresemble RA.2 The studies demonstrated that there are different uptake of HMME withinskin, muscle, synovium, cartilage and b1ood, and the synovium cou1draPidly uPtake more ase than skin and cartilage at the firSt 30 minuesaller intravenous injection of HMME3 The bimaleolar anke width had no different among PDT treated group,H group withollt 1aser and untreated CIA group But hlstologicalevaluation showed statiStical1y significallt reductions in synovialhyperplasia, pannus formation and cart1lage reosion, bone destruction andtotal score in PDT treated group4 Image analysis showed that the ratlo bforeen the areas of the coufltedobect to that of the entire area in PDTtreated grOup is lower than that in conirol group, but the integrated oPticaldensity had no different between the two groups5 Imape analysis showed that the ratio between the area of the countedobject to that of the e

治疗组在大鼠出现踝关节红肿后1周，炎症达到高峰时进行PDT治疗。随机治疗大鼠一侧的踝关节，另。2。一一侧作单纯HMME 对照。治疗方法是大鼠麻醉后尾静脉注入 HMME10ngkg，20分钟后踝关节照光，激光波长627.sum，功率密度 100mwcm'，照射时间1000秒，能量密度100）／。治疗后避光喂养72 小时。隔日一次测量大鼠的踝关节左右横径，治疗后两周取关节进行病理d 观察。 4。大鼠CIA模型用上述方法进行PDT治疗后，治疗组和单纯HMME 组用兔疫组化SP法检测石蜡切片的核增殖抗原。 5。兔AIA模型在关节炎出现第七天进行PDT治疗，随机治疗一侧膝关节，另一侧作自身对照。兔耳静脉注入I'arrainrelomg／Kg，20分钟后，膝关节用金蒸气激光照射，激光能量密度100）儿旷。24 ／J'时后取膝关节滑膜作病理检查，并用脱氧核昔酸末端转移酶介导的缺口末端标记法原位检测凋亡细胞。结果： 1。模型观察：CIA大鼠炎症高峰期滑膜下炎细胞浸润明显，滑膜细胞明显增殖，炎症达到高峰后二周，血管缀形成，并侵蚀和破坏软骨和骨， CIA模型病理改变与人类RA相似。兔AIA模型膝关节滑膜病理可见滑膜细胞增生，滑膜下炎细胞浸润，也与人类RA滑膜改变相似。 2。关节周围组织中光敏剂含量的测定结果表明，各组织对HMME 的吸收速度和吸收量不同，荧光值一时间曲线不同，滑膜组织比皮肤和软骨对 HMME的吸收多，在 2 0分钟时即有明显差异。 3.PDT对CIA模型的治疗结果表明：PDT治疗后关节炎组、单纯 HMME组和治疗组踝关节左右横径统计学检验差异没有显著性，但病理评分PDT治疗组滑膜增生、血管资形成及软骨破坏、骨破坏和总分比关节炎对照组和HMME对照组好，统计学检验差异有显著性。。3＿军医进修学院硕士学位论文中文摘要 4.PDT治疗组PCNA阳性细胞较对照组少，图像分析结果表明面密度（阳性染色的面积总和与统计视野面积的比值）治疗组小于对照组，统计学检验差异有显著性。。 5.PDT治疗组凋亡阳性细胞较对照组明显增多，图像分析结果单位视野内阳性细胞数和面密度PDT治疗组高于对照组，统计学检验差异有显著性。凋亡细胞核直径PDT治疗组较小，与对照组相比，统计学检验差异有显著性。结论：二。CIA、AIA的病理改变类似人类RA，可作为研究RA病因、发病机制、检查及治疗方法的模型。 2。各组织对HMME的吸收速度和吸收量不同，滑膜组织比皮。

The indirect CT finding of the disease are the enlargement of renal pelvis,lymph metastasis and ureteral fistula.CT scan can show the lesions in both the inside and outside of the ureter and is unwounded.

CT检查既可观察腔内病变又可显示腔外肿瘤情况及远处转移，且为无创性检查。

L-Phenylalanine was then obtained by alkylation of N- glycine ethyl ester with benzyl bromide in the presence of an asymmetric phase-transfer catalyst-N-benzyl-cinchonine chloride, followed by hydrolysis of the resulting product.

以甘氨酸乙酯盐酸盐和二苯甲酮为起始原料合成了N-二苯亚甲氨基乙酸乙酯，后者在手性相转移催化剂-N-苄基氯化辛可宁诱导下与烷基化试剂溴化苄发生不对称相转移催化烷基化反应，水解得到L-苯丙氨酸。

If you are unfortunate enough to the lovelorn, please tell me, I will help you out, really, please contact me!

如果你不幸失恋了，请告诉我，我会帮助你摆脱困境，真的，请联系我啦！

China's plan to cut energy intensity by 20 percent and pollutant discharges by 10 percent between 2006 and 2010 is a case in point.

中国计划在2006年到2010间降低20%的能源强度和减少10%的主要污染物排放，就是一个这样的例子。