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The linear acceleration physical training methods used in this experiment have positive effects,while the methods of angular acceleration training need further investigation.

被动训练方法在短时间内对前庭耐受的提高有着很好的效果,本实验中采用一些体训项目,检验这些体训项目对前庭功能的影响,为今后前庭功能训

There was BMP4 expression at E10 in epithelium of otic capsule. Later, BMP4 expressions were affluent in condensed mesenchyme, vestibular cartilage capsule and sense epithelium. 3. The expression pattern of Smad4 in vestibule is different from BMP4. It was not conspicuous until E15 that Smad4 expressed in macula and crista ampullaris and until E16 in periotic cartilage capsule.

BMP4从E10开始,在间充质浓聚前就有表达;间充质一开始浓聚,BMP4在其中就有较丰富的表达;早期主要表达在前庭囊及前庭囊周围的间充质,在胚胎发育的后期,其在软骨囊及前庭上皮里有广泛阳性表达。3。

Aim To study the process of the injury and regeneration of vestibular epithelium of guinea pig after the chronic toxicosis of gentamicin, and to explore the relationship between the vestibular hair cell apoptosis and proliferation, the changes of the expression of protein kinase A,protein kinase Cand the PKC activity of vestibular end organ were observed.

目的 观察慢性庆大霉素中毒后豚鼠前庭上皮的损伤和修复过程,探讨前庭毛细胞凋亡和再生的关系;研究庆大霉素慢性损伤后豚鼠前庭终器蛋白激酶A(protein kinase A,PKA)Cα、Cβ亚型的表达和蛋白激酶C(protein kinase C,PKC)活性的变化及其β_Ⅰ、β_Ⅱ、γ亚型的表达,探讨PKA、PKC与前庭损伤修复的关系;方法 1。

Vestibular compensation is an inevitable process of recovery after vestibular neurectomy.

前庭代偿是前庭神经切断术后患者康复的必然过程,前庭康复训练可缩短前庭代偿的时间。

Vestibule; temporal bone; bony labyrinth; inner ear; perilymph; angular acceleration; hair cells; stereocilia; crista ampullaris; ampulla; cristae; cupula; vertigo; VOR; vestibulo-ocular reflex; vestibular nerve; vestibular nuclei; vestibular ganglion; equilibrium

前庭;颞骨;骨迷路;内耳;外淋巴;角加速度毛细胞;静纤毛;壶腹嵴;壶腹;嵴;吸盘;眩晕;VOR;前庭眼球反射;前庭神经;前庭神经核;前庭神经节;平衡

(1) In common cavity malformation, in addition to the abnormal bony labyrinth such as the cochlea, vestibule and lateral semicircular canal, the inner ear perceptive organ such as the saccule, utricle and scala media were also abnormal.(2) Though we could not identify the basal membrane and sensory epithelia under micro-endoscopy, the utricle and saccule could be clearly identified.(3) During cochlear implantation in common cavity malformation, electrode insertion should be monitored under micro-endoscopy, the electrodes should be put close to the anterior wall of the cavity, otherwise the vestibular organ may be damaged.

(1)共同腔畸形极重度聋患者不仅前庭、外半规管和耳蜗的骨性结构形态发生了变化,而且腔内耳蜗中阶与前庭的球囊、椭圆囊的膜迷路结构形态也发生了变化;(2)微窥镜下分辨不出基底膜或听神经细胞的形态结构,可见畸形前庭的球囊、椭圆囊的囊性结构;(3)进行共同腔畸形人工耳蜗植入手术时,应在耳蜗内镜的监视下,将电极摆放到准确位置,尽可能贴近共同腔的前壁,不应损伤前庭器官。

In contrast, the levels of glutamate and alanine decreased, the level of ghitamine increased in the ipsi-lesional MVN, and the level of glutamate decreased in the contra-lesional MVN of rats 2 weeks after infusing 10 mg arsanilic acid into the tympanic cavity to obstruct m-periphery vestibular organ.

结果提示,单侧迷路破坏后双侧MVN区氨基酸含量立即失去平衡,随着前庭代偿的进展,此差异减少,但是在前庭代偿后却出现双侧前庭核区谷氨酰氨的含量失衡,说明在前庭代偿过程中氨基酸含量变化起着重要作用。

Research of ototoxicity of neomycin to rat vestibular hair cellObjective:To research neomycin ototoxicity for vestibule hair cell of rat, and provide the reference for the pharmacal vestibular dysfunction animal model developement.

本文对前庭功能障碍动物模型的建立、基因导入前庭的方法和Math1基因对药物损害后大鼠前庭感觉上皮毛细胞再生的作用等进行了研究。

And the vestibule function examination also proved that luteolin rivalize vestibule function changes induced by gentamicin.conclusion: based on the experiment,luteolin rivalize ototoxicity induced by gentamicin.

前庭功能检查结果亦发现木樨草素对庆大霉素引起的前庭功能变化有拮抗作用。结论:本实验发现木樨草素对庆大霉素引起的耳蜗和前庭损伤有拮抗作用。

Methods Ten mature Wistar rats were divided into normal control group (5 rats) and adenovirus (E1, E3-Deleted and carried math1 and enhanced green fluorescent protein report gene, Ad-Math1-EGFP) scala vestibuli transfer group (5 rats). Right ears of the Ad-Math1-EGFP transfering group rats were deliveried 5μl Ad-Math1-EGFP (physical tite 2.1×10^11v.p./ml) into cochleas through the way of drilling scala vestibuli of cochlear basal turn. As a control, the normal group received nothing to inner ear. In order to estimate functional condition of vestibule and cochlea, the click-evoked potentials on the surface of the cervical dura mater, auditory brain stem response and swimming time were recorded in all rats at 7 days after treatment, and then histologic and morphologic observation were carried out after animals were sacrificed. Results All animals' morphologic observation showed that inner ear hair cells were normal after transfer.

将10只成年Wistar大鼠分为正常对照组和缺失E1、E3基因片段且构建有Math1基因和绿色荧光蛋白报告基因的复制缺陷型腺病毒(adenovirus-Math1-enhanced green fluorescence protein, Ad-Math1-EGFP)前庭阶导入组,每组5只,实验组大鼠在右耳通过耳蜗底回前庭阶打孔的方法导入物理滴度为2.1×10^11v.p/ml的上述腺病毒5μl,对照组大鼠不做任何处理。7天后对动物进行颈髓硬膜外短声诱发电位(click-evoked potentials on the surface of the cervical dura mater, CDM-CEP)、听性脑干反应阈值检测和游泳试验,评价前庭和耳蜗功能,然后将动物处死进行组织形态学观察。

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