修饰

The recombinant expression plasmids were constructedby fusing theHNP-coding fragment with intein and only the amidation of HNP-2 might beobserved.

通过对HNP-1，HNP-2和HNP-3的研究，在对HNP-2的酰胺化修饰上已获得一定进展。

The recombinant expression plasmids were constructed by fusing the HNP-coding fragment with intein and the amidation of HNP-2 might he observed.

本文采用了一种新的酰胺化方法，即将intein与HNP-2融合表达，intein对目的短肽进行酰胺化修饰。

These studies indicate the rationality of our molecular design based on the crystal structure of KARI complex. To obtain more KARI inhibitors with high activities, the molecular docking and 3D-QSAR methods were applied to our further studying of these amidine compounds. Two methods AutoDock3. 0.3 and DOCK4. 0 were used in molecular docking, and the calculate results accord with that of herbicidal tests in general. The CoMFA model from 3D-QSAR analysis provided useful guidance for designing highly active compounds prior to their synthesis.

这些分子作为潜在的KARI抑制剂为基于KARI的农药分子设计提供了有利指导；对部分小分子进行了合成，在除草活性初筛的近三十个化合物中，个别化合物表现出较好的除草活性，其中一个化合物wb1596对油菜和稗草具有较高的生长抑制率，并通过E.coli KARI酶活性抑制试验验证了其KARI酶的作用靶标，此化合物可以作为KARI一个有苗头的抑制剂为后续工作奠定了基础；对发现的有苗头的KARI抑制剂进行了结构修饰和优化，合成了一系列脒类化合物并确证了它们的结构，改造后的化合物与原抑制剂相比大多除草活性相当或更佳，从而表明我们基于靶标结构的分子设计的合理可靠性；对所合成一系列脒类化合物进行了分子对接和三维定量构效关系研究。

These two electrochemical reactions happens in one polymer macromolecule, which can not only improve the structure of aminoanthraquinone polymer, but also provides a better electrochemical activity.

电催化氧还原技术是化学修饰电极电催化领域研究的热点问题。

A novel method for the separation of aminobenzoic acids by capillary electrophoresis was developed.

报道了一种金纳米修饰毛细管电泳分离、测定氨基苯甲酸的新方法。

The glutamine synthetase produced by the engineering bacteria can specially act on NH4 and aminoglutaric acid, the durability to the high concentration ammonium ion has been distinctively improved because of the dissolution of adenosine acylation modification, the major bottleneck of glutamine with enzymatical production has been solved, and the concentration of the obtained glutamine can reach 47.6g/L.

本发明工程菌产的谷氨酰胺合成酶可专一性的作用于NH 4 和谷氨酸，且因解除了腺苷酰化修饰作用对高浓度铵离子的耐受能力显著提高，解决了酶法生产谷氨酰胺的重要瓶颈，生成的谷氨酰胺的浓度最高达到47.6g/L。

In this study, after 80 day administration with aminoguanidine, AGE in diabetic rats' bone collagen was not obviously reduced.

AGE在肾脏中的积累增多，一方面影响1-α羟化酶的分泌，另一方面直接修饰1-α羟化酶，使其活性降低。1，25-〓生成减少，作为1，25-〓的&促激素&PTH代偿性分泌增加。

Aminoguanidine could not effectively prevent bone mass loss of diabetic rats.

但由于AGE对Ⅰ型胶原的修饰，使其在骨吸收中对蛋白酶水解产生高度抵抗，PTH不能充分发挥骨吸收作用。

Voltammetric behaviors of adrenaline and its beryllium complex in ammoniacal solution;(3). studies of europium at chemically modified electrode and its application in analytical chemistry.

论文分为三部分，即水溶性金属卟啉络合物的电分析化学研究；肾上腺素及其铍络合物的电分析化学研究和铕化学修饰电极的研究及其分析应用。

After the carboxymethylation,the solubility of pachyman in the water was significantly increased,its β-D-glucan characteristic absorption peak at 890 cm-1 became weak obviously,and its methylene vibration absorption peak and CO antisymmetrical stretch vibration absorption peak appeared at 1 333 and 1 606 cm-1 respectively,which indicated that the carboxymethylation succeeded.The analysis of AFM results showed that CMP molecules existed in different morphology under different solution conditions,and that the concentration,ionic strength and solvent physical chemistry characteristics of polysaccharide solution had effects on the CMP chains conformation and the action mode between different molecular chains.The phenomena were considered to be related to hydrogen bond association and intramolecular and intermolecular electrostatic interactions of CMP.

结果表明：经过羧甲基修饰，茯苓多糖在水中的溶解性显著增加，890 cm-1 处的β-D-葡聚糖特征吸收峰明显减弱，1 333 cm-1 处出现次甲基振动吸收峰，1 606 cm-1 处出现〖JG(〗C〖ZJLX，Y〗O〖JG)〗非对称伸缩振动吸收峰，表明羧甲基化成功；原子力显微镜分析表明：在不同溶液条件下，CMP分子以不同形态存在，多糖溶液的浓度、离子强度及溶剂的物化特性均能对CMP的分子链构象及链间相互作用形式产生影响，推测可能与CMP分子内、分子间的氢键缔合及静电作用有关，CMP分子与云母基底间的吸附及静电作用也会对CMP的分子链构象及图像质量产生影响。

Since historical times,England ,where the early inhabitants were Celts, has been conquered three times .

从有历史以来，英国，在此地早期居住的是凯尔特人，已经被征服了三次。

Bluetooth OBEX File Transfer Enables the sending and receiving of files on your phone via Bluetooth.

蓝牙OBEX文件移动允许经过蓝牙传送和接受文件。。。。