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使紊乱

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FSN can raise AA rats low LTT of spleen to normal nearly, remedy the disorder of Th/Ts and Th1/Th2 cells balance in peripheral blood, restrain exorbitant TNF-α、IL-1 produced by PMφ, thereof exert anti-inflammatory and immunoregulation effect.(3) Inside the lesion joints, FSN can depress abnormal hyper-expression of TNF-αmRNA and NF-kB in synovial tissues, as well as advance the expression of Caspase-3 (a proteolytic enzyme of apoptosis), reduce synovial immflammation and proliferation.(4) FSN can lower the expression of VEGF in synovial tissue, reduce neogenetic veins, so inhibit the growth of pannus tissue and the damage of cartilage and bone by that.(5) The above effect of FSN are in proportion to its dosage. Conclusions: FSN has inhibitory effects on symptom and condition of experimental RA, which is better than TWP as a whole.

结果:(1)FSN有明显的抗炎作用,可显著抑制AA大鼠足跖肿胀与多关节炎,改善大鼠的全身情况,同时明显减轻病变关节滑膜炎症与增生,防止关节软骨及骨质的破坏,其综合作用优于TWP;(2)FSN还能使AA大鼠低下的脾LTT恢复至接近正常,纠正外周血中T细胞亚群Th/Ts及Th1/Th2平衡紊乱,抑制大鼠PMφ过高的TNF-α、IL-1分泌,而发挥抗炎和免疫调节作用;(3)在病变关节局部,FSN能显著抑制AA大鼠滑膜细胞异常增高的TNF-αmRNA的表达,降低滑膜组织中NF-kB表达,并增加凋亡蛋白酶Caspase-3表达,从而抑制滑膜的炎症与增殖;(4)FSN还可下调滑膜组织中VEGF表达,减少血管新生,由此抑制血管翳的形成及其对软骨和软骨下骨的侵蚀;(5)FSN的上述作用皆呈现一定的量效依赖关系,高剂量组作用优于低剂量组。

Eating disorders and the female athlete triad increase the risk of osteoporosis; polycystic oary syndrome is associated with future cardioascular risks.

饮食紊乱和运动员三重综合征增加了使女性患骨质疏松的可能;多囊卵巢综合征与患心血管疾病也有一定关系。

Measurement of patellofemoral alignment according to the surface of cartilage was more accurately than that of osseous contour.

通过MRI测量髌股关节软骨面的对合,能使髌股关节紊乱的诊断和治疗得以有效地进行。

Results ①Five days after abdominal application of Xiaoji power(0.1 g per mouce),the medicine showed a very significant effect in enhancing gastrointestinal propulsive function.② Xiaoji powder not only had relaxing effect on the normal smooth muscle in vitro,but also had a strong spasmolytic effect on acetylcholine,green bariuminduced spasm of intestinal smooth muscle.The experiment was based on 10 μg atropine sulfate as a positive control to carry out control experiments.It showed the graphics of atropine sulfate in spasmolytic role.③Xiaoji powder navel paste therapy played a positive role in adjusting the gastrointestinal electric disorder caused by deficiency of spleen Qi,and could restore it to its normal state.

结果 (1)以0.1 g/只消积散给予小鼠腹部用药5 d,即显示非常显著的增强胃肠推进功能作用;(2)消积散不仅对正常离体平滑肌有舒张作用,同时对由于乙酰胆碱、氯化钡引起的肠平滑肌痉挛也有强的解痉作用,该实验是以硫酸阿托品10 μg作为阳性对照药进行对照实验,显示了硫酸阿托品的解痉作用图形;(3)消积散敷脐对脾虚引起的胃肠电紊乱有明显的调节作用,使脾虚大鼠的胃肠电基本恢复到正常状态。

So hyperinsulinemia may step up blood pressure.These explain IR have some invariable effect in pathogenesis of eclampsism. Sex hormone binding globulin is a species of sterin haptoglobulin which is form from liver.The level of SHBG is an indirect index of balanate between androgen and estrogen.Not only hyperinsulinemia but also IR have intimate relationship with blood serum SHBG level.

高胰岛素血症、胰岛素抵抗与血清SHBG水平均有着密切关系,胰岛素对调节SHBG的代谢具有重要意义,胰岛素水平升高使SHBG生成减少,造成体内性激素水平紊乱,导致糖、脂肪、胰岛素代谢障碍,提示SHBG是高胰岛素血症、胰岛素抵抗的一个特有标志。

Breath fails (Respiratory Failure, because lung aerates,RF) is obstacle of function of insufficient, dispersion and lung aerate / blood stream scale is maladjusted wait for an element, low oxygen blood appears when making static interest position issues breath disease and carbon dioxide retention, cause a series of physiology functions and metabolization thereby disorder clinical and integrated proof.

概要: 呼吸衰竭(respiratory failure,RF)是由于肺通气不足、弥散功能障碍和肺通气/血流比例失调等因素,使静息状态下呼吸时出现低氧血症和二氧化碳潴留,从而引起一系列生理功能和代谢紊乱的临床综合征。

Fat can directly damage the function of the insulin cells and makes them insufficiently to play their sugar capitulating function, leads to the turbulence of insulin support and sugar metabolizing, then causes the diabetes.

肥胖直接带来对胰岛素细胞功能的损害,使之不能充分发挥降糖作用,导致胰岛素抵抗和糖代谢紊乱,引发糖尿病。

October proved a riot to the senses and climaxed those giddy last weeks before Halloween.

十月使我的感官紊乱,万圣节前几周,这种晕眩达到高潮。

Results: Compared with control dogs, sections from AF dogs showed cellular hypertrophy, disarranged cell bundles and increasing connective tissue.

结果:与对照犬相比,AF犬肺静脉肌袖内心肌细胞增大、排列紊乱;细胞核大小不甚规则,核异型性明显,细胞内可见肌纤维断裂;心肌纤维之间连接组织积聚,使心肌细胞之间的间隔增宽。

The Al-Al2Cu eutectic were disorganized and furcated by high magnetic field, which in turn accumulated inner stress and gave rise to the apparent increase of the dislocation densities.

强磁场影响了定向凝固Al-Al2Cu共晶合金的生长过程,使其组织变得紊乱扭曲,晶粒内部应力增加,产生了大量位错。

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He and Nina moved to California and lived at 2005 Ivar Street, Apt.

他和Nina搬到加州,并在2005年伊瓦尔街,公寓生活。

Droperidol ( potently inhibits transfected HERGchannels and this is the probable mechanism for QT prolongation.

氟哌利多有效地抑制了转染的 HERG 钾通道,可能是 QT 间期延长的机制。

The Nazi's cruel treatment of the Jews during the Second World War is beneath contempt .

二战期间纳粹对犹太人的暴行极其可鄙。