查询词典 technical knockout

To define the role of insulin action in the central nerous system in regulating the counterregulatory response to hypoglycemia, mice with a brain/neuron-specific insulin receptor knockout and littermate controls were subjected to 90-min hyperinsulinemic (20 mU · kg–1 · min–1)-hypoglycemic (1.5 mmol/l) clamps.

为了证实中枢神经系统的胰岛素在低血糖反应的调节作用，对中枢神经胰岛素受体敲除的小鼠和对照组小鼠进行了高胰岛素（20 mU · kg–1 · min–1）-低血糖(1.5 mmol/l)的钳夹试验。

Molecular techniques such as gene knockout partially support the monoamine theory of depression.

诸如基因部分敲除的分子技术支持抑郁症的单胺理论。

The knockout mice were more susceptible to cisplatin-induced nephrotoxicity, and this was blunted by N-acetyl-cysteine pretreatment.

人的基因敲除小鼠更容易顺铂所致肾毒性，这是减弱的N -乙酰半胱氨酸预处理。

We compared the responses of Nrf2-knockout mice and their wild-type littermates in established mouse models of ischemia-reperfusion injury and cisplatin-induced nephrotoxicity.

我们的反应比较Nrf2与敲除小鼠和野生型窝在建立小鼠模型的缺血再灌注损伤和顺铂所致肾毒性。

Although these data in noway eliminate the possibility of the involvement of the NMDARGluR 1 subunit in mediation of ketamine anesthesia/hypnosis,they suggest the difficulties with interpretation of alteredanesthetic sensitivity in knockout animal models.

尽管这些结果并不能否定 NMDA 受体的 GluRε1亚基参与介导氯胺酮麻醉/催眠作用的可能性，但是可以提示用基因敲除动物的麻醉药敏感性改变来分析麻醉作用较为困难。

It's a one-legged straight knockout match, meaning that the result will be decided on the night.

这是一个一条腿的直接淘汰赛的比赛，这意味着结果将在当晚决定。

Therefore,it is importance task that we should not only knockout α-1,3GT and relative molecules from pigs,but also ensure safety in public health of XP from PERV.

因此，即要剔除导致人类排异反应的猪细胞表面的α-1，3GT及其相关的分子，又要确保猪器官异种移植的安全性，是尚待研究的重大课题。

Thereafter,DNA fragment of Hyl-1-Amp-Hyl-1 was subcloned into pBR322 vector,the resulting construct was then checked by PCR and restriction analysis for the proper configuration of the knockout vector pBR322-SA.

该载体与质粒pBR322分别用EcoRⅠ、PstⅠ双酶切后进行连接，得到基因敲除的重组载体pBR322SA，PCR 及限制性酶切分析，构建的敲除载体与设计结果相符。

The 32 participating member associations will be offered 12% of the purchasable tickets for each of their matches (previously 8%) in the group phase and an average of 8% in the knockout phases.

在小组赛阶段，进入决赛圈的32强成员国会各自分配到"该国参加的比赛的可购票数"的12%（过去是8%）；而进入淘汰赛阶段，各国会分配到8%。

They face Tottenham Hotspur in the Carling Cup final on 1 March, and have also reached the first knockout phase of the Champions League as well as the FA Cup fifth round, but Ferguson insists a quintuple might be "impossible".

他们将在下月1日在联赛杯决赛上迎战热刺，而冠军杯也进入了淘汰赛阶段。足总杯也开打了。但弗格森爵士坚持认为五冠是不可能的。

"Second Life is remarkably easy to work with, and is very popular,"

"第二次生命是显着容易的工作，并且很受欢迎，"

For example, we usually assume that materials are homogeneous and isotropic and free of internal defects or flaws.

为了得到适合有限元分析的模型，我们必须经过如图2所示的简化步骤。