查询词典 technical knockout

Pylori, we mutated minD gene by insertional mutagenesis and knockout minE gene of H.

此两种突变株的形态都转变成细丝状的菌体。

To study the role of FoxO1 on myoblast proliferation and differentiation and the transformation of muscle fiber type in porcine,here we use yorkshire as experimental materials and detect the expression of genes related myogenesis and muscle fiber type in pporcine myoblast that was knockout or activated FoxO1,adopting the technology of RNAi,real time-PCR and Western blotting et al..

为探讨FoxO1对猪成肌细胞增殖分化及肌纤维类型转化的作用及机理，本试验以大白猪为研究材料，利用RNAi、real-time PCR、免疫细胞化学和Western blotting等技术，通过在原代培养的猪成肌细胞中敲除和激活内源活性FoxO1，检测肌肉形成与肌纤维类型相关基因的表达。

Although heart wall thickness was reduced overall, specific areas exhibited morphological changes consistent with myxomatous degeneration in the walls of knockout hearts.

尽管整体心室壁厚度下降，但是特定区域的形态学改变和基因敲除小鼠的心室壁粘液瘤的形成一致。

So far transgenic knockout models of AQP1, AQP3, AQP4 and AQP5, and a knock-in model introducing a point mutation (T126M) that causes autosomal recessive nephrogenic diabetes insipidus in human have been successfully established. Significant progresses have been made in characterizing the physiological functions of these AQPs by systematic mouse phenotype studies.

目前AQP1、3、4、5基因敲除和AQP2基因点突变的基因敲入小鼠模型（模拟人类常染色体隐性遗传尿崩症）已成功建立并广泛用于表型研究，在AQP水通道蛋白生理功能方面获得许多重要进展。

But that achievement pales in comparison to the team's progress to the knockout stages.

不过，球队更令人激动的无疑是闯进世界杯淘汰赛。

PartⅠGenistein thwarts the development ofatherosclerosis in LDLR-knockout mice BACKGROUND: Artherosclerosis and its complication are one of the maincauses for pathopoiesis and death.

第一部分Genistein对LDLR-／-小鼠动脉粥样硬化发生发展的影响研究背景动脉粥样硬化(artherosclerosis，AS)及其并发症是人群致病和死亡的重要原因之一。

It is estimated that there are about 40,000 functional genes.In order to understand those genes related to human diseases and the novel functional genes, the genetic manipulated mice including transgenic mice and knockout mice have been generated to facilitate the purpose.This transgenic core has been collaborated with industrial and research institutes for years, and has built up competitive know-how for transgenic mice, embryo cryopreservation, and pathogen free rederivation.

小鼠长期以来即为研究人类疾病最佳动物模式，2001年美国赛洛因公司已将小鼠129的两个品系之基因序列解码完成提供付费使用，2003年小鼠B6的基因序列也被Mouse Genomic DNA Sequencing Consortium解码完成，预估约有4万个功能基因，随著基因操控技术的成熟，制造出各种带不同基因缺陷的模式动物供生物医学研究已非难事。

He trix indicator may be a little slower, but when signals are given, they are VERY reliable and come with devastating "knockout" power.

RIX指标可能要慢一些，但是一旦信号给出，就很可靠，给出全然震撼性的威力。

Anti-filament immunofluorescence indicated the distribution of primary vestibular neuron endings in vestibular sensory epithelium and the contacts between it and hair cells were normal.These results indicated that Smad4 conditional knockout mice were generated successfully, whose morphological and pathological changes in vestibulum auris internae were slightly.

该研究提示，软骨组织Smad4条件基因敲除小鼠动物模型造模成功；Smad4条件基因敲除小鼠的内耳前庭形态轮廓基本正常但细节上有一定程度的畸形，纯合子小鼠前庭末梢感受器病理改变轻微。

The draw for the first knockout round of the Champions League will take place on Friday December 15 in Nyon.

第一轮小组出线的抽签将会在12月15日在瑞士的尼翁举行。

"Second Life is remarkably easy to work with, and is very popular,"

"第二次生命是显着容易的工作，并且很受欢迎，"

For example, we usually assume that materials are homogeneous and isotropic and free of internal defects or flaws.

为了得到适合有限元分析的模型，我们必须经过如图2所示的简化步骤。