查询词典 suppressor

In the lung cancer cell line A549, Folliculin is expressed in the cytoplasm and BHD gene is a metastasis suppressor gene.

BHD表达产物Folliculin蛋白在肺癌细胞的胞质内表达，BHD可能是肺癌转移抑制基因。

In addition, germ-line epimutations of other tumor suppressor genes, such as MSH2 and BRCA1, have also been reported, demonstrating that epimutations might arise in the germ-line (during gametogenesis or early embryonic development).

随后，关于其他抑癌基因MSH2与BRCA1等的胚系异常甲基化也陆续有报道。这提示，表观突变也可以起源于胚系（生殖细胞形成期或胚胎发育早期），从而造成全身细胞广泛的基因转录沉默。

Objective To study the relationship between tumor suppressor gene p16 and the generation and development of gynecologic malignancies.

目的：探讨抑癌基因p16与原发性妇科恶性肿瘤发生发展的关系。

Objective Loss of heterozygosity of tumor suppressor gene is believed to play a key role in carcinogenesis of colorectal cancer.

目的抑癌基因的杂合缺失被认为是结直肠癌形成的通路之一，本实验拟通过对染色体10q23～24区的LOH分析，发现高频杂合缺失区域并筛查与结直肠癌相关的抑癌基因。

AIM: To investigate the expression of phosphatase and tension homologue deleted on chromosome 10, the tumor suppressor gene PTEN, in ectopic endometrium in patients with endometriosis and to study the role of PTEN in the pathogenesis of the disease.

目的：检测第10号染色体缺失的磷酸酶和张力蛋白同源物基因在子宫内膜异位症中的表达，探讨其在EMS发病机制中的作用。

The expression absence of LRRC4 was ascribed to the loss of homozygosity of 7q32-ter in U251 cell lines. Conclusion The expression of LRRC4 gene is absent in glioblastoma cell lines, and it offers the important experiment proof for LRRC4 to act as a new candidate of brain tumor suppressor gene from glioma.

通过对胶质瘤细胞系基因组DNA中LRRC4的ORF序列的PCR扩增和测序分析，发现SF126，SF767，M17细胞中，ORF序列第279位氨基酸的第3个密码子存在同义点突变(3/5)，而U251和U87细胞基因组DNA中发生了LRRC4基因的缺失突变(2/5)。

DNA methylation is one of the important mechanisms that lead to the inactivation of tumor suppressor genes.

在癌变的过程中抑癌基因表达的改变可能首先表现DNA甲基化状态的异常。

The gene encoding p16 mayn't be the primary target of LOH at 9p21-22 in HNSCC, implicating the existence of additional tumor suppressor genes at this locus involved in the pathogenesis of HNSCC.

编码p16蛋白的基因可能并不是HNSCC在9p21-22区域发生LOH的唯一靶基因。9p21-22区域可能还存在与HNSCC发生发展有关的其它抑癌基因。

My Name is Sam - 25gp Neutralize 5 terrorists in a row by performing headshots using a Sound Suppressor.

武器在装著灭音器的情况下，以爆头的方式连续击毙5个恐怖分子

The neurofibromatosis type 2 (NF2) tumor suppressor is the only gene known to be frequently involved in early development of meningiomas.

多发性神经纤维瘤2型(NF2)肿瘤抑制基因是已知唯一的经常出现在脑膜瘤早期发展过程中基因。

But GST= 0.156, Nm=1. 588. As a result, the foundation of Youyongchi Avicennia marina population was the result of the migration of hypocotyles and human factors.

这项工作可以为海岸防护林中新引进种类的判定以及为研究种群建立者效应方法的确定提供科学依据。

The two-dimensional CDRC-ADI-FDTD update equations for collision unmagnetized plasma are induced. The unconditional stability of the CDRC-ADI-FDTD formulation for collision unmagnetized plasma is obtained by the examples.

推导了碰撞非磁化等离子体中的二维CDRC-ADI-FDTD迭代公式，并用算例验证了碰撞非磁化等离子体CDRC-ADI-FDTD算法也是无条件稳定的。