查询词典 suppressor

This subset is hyporesponsive and anergic to antigen stimulation. Recently, it has been demonstrated to participate in the immune deficiency in human immunodeficiency virus infection and has close relationship with the development of acquired immunodeficiency syndrome. Meanwhile, the CD4(superscript +)D25(superscript +)Treg is also infected when the human body is invaded by HIV. The CD4(superscript +)CD25(superscript +)Treg will finally be killed by the mechanism of antibody-dependent cell-mediated cytotoxicity. Because of the decrease of the CD4(superscript +)CD25(superscript +)Treg, it can't function as a immune suppressor as a result of the excess of activation of HIV and gradually exhausting of the T cell, which shows that the CD4(superscript +)CD25(superscript +)Treg plays a inhibitory role in the different stages of the development of the HIV as well as different effects in the pathogenesis of AIDS.

它能够抑制自身免疫病的发生和发展，参与肿瘤免疫的调节，同时在感染和移植免疫中也发挥着极其重要的作用。T细胞的这一亚群具有免疫调节和免疫抑制的特性，新近发现它亦与爱滋病的发生、发展关系密切HIV进入人体后，CD4D25调节性T细胞抑制了机体的免疫效应但它也同时被感染，最终由于细胞毒的作用而死亡由于调节性T细胞数量的减少不能有效的发挥其抑制作用，HIV持续的过度活化使得T细胞逐渐耗竭说明在HIV发生、发展的不同阶段Treg细胞可能都发挥了免疫抑制作用，但是却对HIV感染与爱滋病发病的进程产生了不同的效应。

Accession Number: AF151005.Conclusion A single-copy fragment containing cis-acting "CACA" box has been identified, which might be the upstream of a new tumor suppressor gene deleted in tumors of the stomach and small intestine.

在胃、小肠肿瘤组织发生缺失突变的片段可能为某一抑癌基因的前半部分，即含有启动子成分的调控元件部分CACA盒。

To remove these safety hazards, an automatic gasproducing dry powder explosion suppression system has been developed through technical improvement. The system which consists of ultraviolet sensor, controller and explosive suppressor, can be effectively used in open or half open area with some explosive gas or combustive powder.

CNG加气站现有消防设施动作时间长，不能有效防止天然气的爆炸，为此，开发研制了产气式自动干粉抑爆系统，由紫外传感器、控制器、抑爆器组成，可用于爆炸性气体场所的敞开或半敞开空间抑爆。

It is well-known that for eucaryotic cells, DNA is located in the karyon and can not penetrate to the cytochylema and the tissue fluid because the cell membrane can act as barriers for DNA transportation. Therefore, the appearance of DNA in cell matrix and the serum can indicate that some diseases have taken place. A main reason for cancer occurrence is the mutation of DNA. It may cause the change of the sequence and expression of cancer suppressor genes.

真核细胞的DNA广泛的存在于细胞核内的染色体上，由于核膜的选择性通透作用，使DNA无法分散到其它细胞的亚器官，加之细胞膜的隔离效果，DNA更难扩散到细胞外基质中，因此细胞外基质中DNA含量的增加往往也会预示某些疾病的发生。

Objective: To explore the inhibition effects of ectogenic wild-type p53 cDNA (Ad-wtp53) on colorectal carcinoma cell lines with different p53 gene status and search for the role of wild type p53 tumor suppressor gene in occurrenc and progress of malignant tumor.

目的：探索重组腺病毒介导的外源性野生型p53cDNA(Ad-wtp53)对内源性p53基因状态不同结直肠癌细胞的抑制作用是否存在差异，研究p53基因抑制肿瘤细胞增殖的机制。

To study the regulation mechanism of SOCS-3 (Suppressor of cytokines signals-3) for erythropoietic development, small interference RNA expression vectors of SOCS-3 were constructed and transferred in to the K562 cell lines stably by lentiviral system.

为了研究细胞因子信号转导分子3(suppressor of cytokine signals-3，SOCS-3)对造血发育的影响，构建了SOCS-3慢病毒siRNA干涉载体，并转染人红白血病细胞株K562。

Nasopharyngeal carcinoma is an endemic cancer with particulargeographic and ethnic distribution within southern China, most frequently, withinGuangdong province. Etiologically, the disease involves multiple factors includinggenetic, Epstein-Barr viral, as well as other food and environmental factors.Cytogenetic studies have revealed that loss of heterozygosity on chromosome3p occurred in as many as 95 - 100％ of NPCs and 75％ of precancerous lesions,suggesting the presence of NPC associated tumor suppressor genes.

鼻咽癌(Nasopharyngeal carcinoma，NPC)是中国南部、尤其是广东省最为常见的恶性肿瘤，其发病与遗传因素、EB病毒感染、以及环境和饮食等多种因素有关。3号染色体短臂(3p)在高达95-100％的鼻咽癌和75％的癌前病变中发生杂合性丢失(Loss of heterozygosity，LOH)，提示3p缺失区域中存在与鼻咽癌发生密切相关的抑癌基因。

AIM To evaluate the relationship between microsatellite inst ability and loss of heterozygosity of tumor suppressor genes in gast ric carcinomas.

目的 研究微卫星不稳和抑癌基因缺失在胃癌发生中的作用。

The data obtained indicated the presence of putative tumor suppressor geneat chromosome 1p and was valuable for fine mapping,cloning or candidate identification o...

为抑癌基因的精确定位、克隆或鉴定提供了有价值的参考资料。

Chinese patent medicine ; Zilongjin ; hexamethylene bisacetamid ; cell cycle ; oncogenes ; genes ; tumor suppressor

中成药；紫龙金；环六亚甲基二己酰胺；细胞周期；癌基因；基因；肿瘤抑制

We are forbidden from giving money to these shoeless, skinny children, as this will perpetuate begging.

向光着脚，骨瘦如柴的孩子施舍是不可以的，因为要招来无休无止的乞讨。

It would be hard not to fall victim to some sharpeyed policeman.

要想不被某个目光锐利的警察抓到，谈何容易。